Page last updated: 2024-09-05
pld118 and fluconazole
pld118 has been researched along with fluconazole in 1 studies
Compound Research Comparison
| Studies (pld118) | Trials (pld118) | Recent Studies (post-2010) (pld118) | Studies (fluconazole) | Trials (fluconazole) | Recent Studies (post-2010) (fluconazole) |
|---|---|---|---|---|---|
| 13 | 0 | 2 | 9,343 | 721 | 3,664 |
Protein Interaction Comparison
| Protein | Taxonomy | pld118 (IC50) | fluconazole (IC50) |
|---|---|---|---|
| Lanosterol 14-alpha demethylase | Candida albicans SC5314 | 0.1296 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 9.21 | |
| Sterol 14-alpha demethylase | Trypanosoma cruzi strain CL Brener | 0.88 |
Research
Studies (1)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Bacher, J; Groll, AH; Kelaher, AM; Mickiene, D; Petraitiene, R; Petraitis, V; Sarafandi, AA; Sein, T; Walsh, TJ | 1 |
Other Studies
1 other study(ies) available for pld118 and fluconazole
| Article | Year |
|---|---|
Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans.
Topics: Animals; Antifungal Agents; Area Under Curve; Candida albicans; Candidiasis; Candidiasis, Oral; Cycloleucine; Drug Resistance, Fungal; Enzyme Inhibitors; Esophageal Diseases; Female; Fluconazole; Half-Life; Immunosuppression Therapy; Isoleucine-tRNA Ligase; Rabbits | 2004 |