piperaquine has been researched along with primaquine in 43 studies
| Studies (piperaquine) | Trials (piperaquine) | Recent Studies (post-2010) (piperaquine) | Studies (primaquine) | Trials (primaquine) | Recent Studies (post-2010) (primaquine) |
|---|---|---|---|---|---|
| 638 | 227 | 497 | 2,196 | 196 | 711 |
| Protein | Taxonomy | piperaquine (IC50) | primaquine (IC50) |
|---|---|---|---|
| Cytochrome P450 1A2 | Homo sapiens (human) | 0.1824 | |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | 7.5 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.016 | |
| Serine hydroxymethyltransferase, mitochondrial | Homo sapiens (human) | 0.4365 | |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | 2.9 | |
| 60 kDa chaperonin | Escherichia coli | 6.2 | |
| 10 kDa chaperonin | Escherichia coli | 6.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (9.30) | 29.6817 |
| 2010's | 28 (65.12) | 24.3611 |
| 2020's | 10 (23.26) | 2.80 |
| Authors | Studies |
|---|---|
| Masseno, V; Muriithi, S; Nzila, A | 1 |
| Fidock, DA; Flannery, EL; Winzeler, EA | 1 |
| Bane, CE; Black, C; Butler, K; Caridha, D; Cooper, RA; Dodean, RA; Gaona, H; Gaynor-Ohnstad, L; Huezo, SJ; Kancharla, P; Kelly, JX; Kreishman-Deitrick, M; Leed, SE; Li, Q; Li, Y; Lin, H; Luong, TL; Marcsisin, S; Melendez, V; Nolan, C; Olmeda, R; Potter, B; Pou, S; Rasmussen, SA; Read, L; Riscoe, MK; Roncal, N; Sciotti, RJ; Smilkstein, MJ; Sousa, J; Stephens, MT; Tan, JC; Vesely, B; Vuong, C; Winter, RW; Xie, L; Zeng, Q; Zhang, J; Zhang, P | 1 |
| Cheong, SL; Ng, CH; Tibon, NS | 1 |
| Bane, CE; Bayles, BR; Black, C; Butler, K; Caridha, D; Ceja, FG; Cooper, RA; Dodean, RA; Gaona, H; Gaynor-Ohnstad, L; Kancharla, P; Kelly, JX; Kreishman-Deitrick, M; Leed, SE; Li, Q; Li, Y; Lin, H; Luong, TL; Marcsisin, S; Melendez, V; Mu, J; Nolan, C; Olmeda, R; Potter, B; Pou, S; Pybus, B; Rasmussen, SA; Read, L; Reynolds, KA; Riscoe, MK; Roncal, N; Rosenthal, PJ; Sciotti, RJ; Smilkstein, MJ; Sousa, J; Tumwebaze, PK; Vesely, B; Vuong, C; Xie, L; Zeng, Q; Zhang, J; Zhang, P | 1 |
| Huang, JZ; Lan, XH; Xu, WZ | 1 |
| Binh, TQ; de Vries, PJ; Giao, PT; Hung, le Q; Kager, PA; Nam, NV | 1 |
| Ashton, M; Friberg Hietala, S; Hai, TN; Röshammar, D; Van Huong, N | 1 |
| Brittenham, GM; Kano, S; Krudsood, S; Li, G; Looareesuwan, S; Pengruksa, C; Phophak, N; Tangpukdee, N; Thanachartwet, V; Wilairatana, P | 1 |
| Dara, P; Deng, C; Jian, H; Li, G; Ou, F; Seila, S; Socheat, D; Sokunthea, S; Song, J; Tan, B | 1 |
| Baird, JK; Basri, H; Ekawati, LL; Elyazar, I; Farrar, J; Meilia, RA; Nurleila, S; Putri, FA; Setiabudy, R; Sudoyo, H; Sutanto, I; Taylor, WR; Tjahjono, B | 1 |
| Chavez, I; Chokejindachai, W; Dondorp, AM; Imwong, M; Pasaribu, AP; Pasaribu, S; Sirivichayakul, C; Tanomsing, N; Tjitra, E; White, NJ | 1 |
| Gogtay, N; Kannan, S; Olliaro, PL; Sinclair, D; Thatte, UM | 1 |
| Ashley, EA; Chotsiri, P; Day, NP; Hanboonkunupakarn, B; Hanpithakpong, W; Jittamala, P; Lee, SJ; Panapipat, S; Pukrittayakamee, S; Tarning, J; Wattanakul, T; White, NJ | 1 |
| Affara, M; Amambua-Ngwa, A; Bousema, T; D'Alessandro, U; DiTanna, G; Drakeley, C; Eziefula, AC; Jawara, M; Nwakanma, D; Okebe, J; Van Geertruyden, JP | 1 |
| Eckhoff, P; Gerardin, J; Wenger, EA | 1 |
| Cabrera, M; Cui, L | 1 |
| Baber, I; Bousema, T; Brown, JM; Chen, I; Diawara, H; Dicko, A; Gosling, R; Hwang, J; Keita, S; Koita, F; Lanke, K; Mahamar, A; McCulloch, C; Niemi, M; Nosten, F; Pett, H; Poirot, E; Sanogo, K; Soumare, HM; Traore, SF | 1 |
| Aubry, P; Gaüzère, BA; Ouledi, A; Toyb, M | 1 |
| Elvina, E; Kajeechiwa, L; Kyawt, K; Min, JR; Nosten, F; Nosten, S; Oo, PT; Peapah, P; PoWah, W; Shee, PW; Thwin, MM; von Seidlein, L; Wiladphaingern, J; Yee, NL | 1 |
| Affara, M; Badji, H; Bousema, T; Correa, S; D'Alessandro, U; Dabira, E; Di Tanna, GL; Drakeley, C; Gaye, A; Nwakanma, D; Okebe, J; Sanya-Isijola, F; Van Geertruyden, JP | 1 |
| Blessborn, D; Chotsiri, P; Day, NPJ; Hanboonkunupakarn, B; Hoglund, RM; Jittamala, P; Pukrittayakamee, S; Tarning, J; Wattanakul, T; White, NJ | 1 |
| Anstey, NM; Douglas, NM; Kenangalem, E; Malloy, MJ; Patriani, D; Poespoprodjo, JR; Price, RN; Simpson, JA; Soenarto, Y; Sugiarto, P | 1 |
| Alano, P; Bousema, T; Bradley, J; Brown, J; Chen, I; Diawara, H; Dicko, A; Drakeley, C; Gosling, R; Graumans, W; Lanke, K; Mahamar, A; Nyaurah, M; Oriango, R; Osodo, P; Osoti, V; Rijpma, S; Sawa, P; Siciliano, G; Stone, W; van de Vegte-Bolmer, M; Woestenenk, R | 1 |
| Day, NPJ; Dondorp, AM; Hien, TT; Le Phuc-Nhi, T; Phu, NT; Son, DH; Thuy-Nhien, N; Thwaites, GE; Tran, NH; Tuyen, NTK; Van Dung, N; Van Quan, B; von Seidlein, L; White, NJ | 1 |
| Abello Peiri, C; De Smet, M; Debackere, M; Eam, R; Ken, M; Khean, C; Khim, N; Kim, S; Kindermans, JM; Menard, D; Nguon, C; Rossi, G; Van den Bergh, R; Van, V; Vernaeve, L | 1 |
| Adams, M; Bousema, T; Chalon, S; Collins, KA; Elliott, S; McCarthy, JS; Mitchell, H; Möhrle, JJ; Rampton, M; Reuling, IJ; Sauerwein, R; Wang, CY | 1 |
| Bousema, T; Bradley, J; Brown, JM; Chen, I; Diarra, K; Diawara, H; Dicko, A; Drakeley, C; Gosling, R; Hwang, J; Issiaka, D; Keita, S; Kone, DT; Lanke, K; Mahamar, A; McCulloch, C; Müller, O; Roh, ME; Sanogo, K; Soumare, HM; Srinivasan, V; Stone, WJR; Traore, SF | 1 |
| Bacar, A; Deng, C; Fay, MP; Feng, D; Huang, B; Huang, S; Kéké, RA; Li, D; Li, G; Li, XB; Lin, L; Liu, XH; Lu, F; Mohadji, F; Mohamed, M; Msa Mliva, A; Oithik, F; Said Abdallah, K; Song, J; Su, XZ; Tuo, F; Wang, Q; Wang, X; Wellems, TE; Wu, W; Wu, Z; Xu, Q; Xue, L; Yan, H; Yang, T; Zhang, H; Zheng, S; Zhou, J | 1 |
| Blessborn, D; Chairat, K; Day, NPJ; Hanboonkunupakarn, B; Hanpithakpong, W; Jittamala, P; Pukrittayakamee, S; Tarning, J; White, NJ | 1 |
| Cen, YZ; Deng, ZH; Li, XH; Liao, YB; Lin, RX; Liu, MR; Pan, B; Pei, FQ; Ren, WF; Ruan, CW | 1 |
| Chann, S; Fukuda, MM; Gosi, P; Kuntawunginn, W; Lin, J; Lon, C; Manning, J; Rekol, H; Satharath, P; Saunders, D; Sinoun, M; Smith, PL; So, M; Somethy, S; Soveasna, K; Spring, M; Sriwichai, S; Wojnarski, M | 1 |
| Ali, AS; Ali, SM; Aydin-Schmidt, B; Bennett, A; Björkman, A; Hodzic, L; Islam, A; Jovel, I; Khamis, M; Magnusson, E; Mårtensson, A; Mkali, H; Morris, U; Msellem, MI; Poirot, E; Sachs, MC; Shija, SJ; Tarning, J | 1 |
| Bancone, G; Carrara, VI; Chu, CS; Imwong, M; Jeeyapant, A; Lee, SJ; Nosten, F; Paw, MK; Phyo, AP; Poe, NP; Proux, S; Raksapraidee, R; Sriprawat, K; Tarning, J; Thinraow, S; Turner, C; Watson, J; White, NJ; Wiladphaingern, J; Wilairisak, P; Win, HH; Yotyingaphiram, W | 1 |
| Abreha, T; Adam, I; Anstey, NM; Assefa, A; Awab, GR; Baird, JK; Barber, BE; Chu, CS; Commons, RJ; Dahal, P; Daher, A; Davis, TME; Dondorp, AM; Grigg, MJ; Guerin, PJ; Hien, TT; Humphreys, GS; Hwang, J; Karunajeewa, H; Laman, M; Lidia, K; Moore, BR; Mueller, I; Nosten, F; Pasaribu, AP; Pereira, DB; Phyo, AP; Poespoprodjo, JR; Price, RN; Sibley, CH; Simpson, JA; Stepniewska, K; Sutanto, I; Thriemer, K; Thwaites, G; White, NJ; William, T; Woodrow, CJ | 1 |
| Davidson, SA; Day, NPJ; Dondorp, A; Hanboonkunupakarn, B; Hoglund, RM; Jittamala, P; Kobylinski, KC; Mukaka, M; Pantuwatana, K; Phasomkusolsil, S; Pukrittayakamee, S; Tarning, J; van der Pluijm, RW; White, NJ; Winterberg, M | 1 |
| Adhikari, B; Cobelens, F; Day, NPJ; Dhorda, M; Dondorp, AM; Henriques, G; Imwong, M; Mayxay, M; Mukaka, M; Newton, PN; Peerawaranun, P; Peto, TJ; Phommasone, K; Pongvongsa, T; Promnarate, C; Sirithiranont, P; van Leth, F; von Seidlein, L; White, NJ | 1 |
| Adhikari, B; Cheah, PY; Chotivanich, K; Cobelens, F; Davoeung, C; Day, NPJ; Dhorda, M; Dondorp, AM; Hanboonkunupakarn, B; Hien, TT; Imwong, M; Jittmala, P; Kajeechiwa, L; Landier, J; Lwin, KM; Mayxay, M; Mukaka, M; Newton, PN; Nguon, C; Nguyen, TN; Nosten, FH; Nosten, S; Parker, DM; Peerawaranun, P; Peto, TJ; Phommasone, K; Pongvongsa, T; Promnarate, C; Proux, S; Pukrittayakamee, S; Rekol, H; Thwaites, GE; Thwin, MM; Tripura, R; van Leth, F; von Seidlein, L; White, NJ; Wiladphaingern, J | 1 |
| Akakpo, S; Chalon, S; Chughlay, MF; Csermak-Renner, K; Djeriou, E; Gaur, AH; Leboulleux, D; McCarthy, J; Odedra, A; Shanks, GD; Winnips, C | 1 |
| Arsanok, M; Chann, S; Dysoley, L; Jongsakul, K; Kheang Heng, T; Kuntawunginn, W; Lin, JT; Lon, C; Manning, JE; Nou, S; Pichyangkul, S; Satharath, P; Saunders, DL; Sea, D; Smith, PL; Sok, S; Spring, MD; Sriwichai, S; Vanachayangkul, P; Waters, NC; Wojnarski, M | 1 |
| Ashley, EA; Aung, H; Aung, Y; Day, NPJ; Dondorp, AM; Heaton, J; Hlaing, T; Imwong, M; Indrasuta, C; Khant, ZS; Kyaw, TT; Maung, SM; McLean, ARD; Phyo, AK; Smithuis, FM; Soe, K; Swe, MMM; Tun, KM; Tun, NN; von Seidlein, L; White, NJ | 1 |
| Bousema, T; Brown, JM; Chen, I; Chotsiri, P; Diawara, H; Dicko, A; Gosling, R; Hoglund, RM; Koita, F; Mahamar, A; Sanogo, K; Simpson, JA; Tarning, J; White, NJ | 1 |
| Baird, JK; Berni, A; Budiman, W; Cedar, E; Chand, K; Crenna-Darusallam, C; Duparc, S; Ekawati, LL; Elyazar, I; Fernando, D; Fletcher, K; Goyal, N; Green, JA; Instiaty, I; Jones, S; Kleim, JP; Lardo, S; Martin, A; Noviyanti, R; Prasetya, CB; Rolfe, K; Santy, YW; Satyagraha, AW; Sharma, H; Soebandrio, A; Subekti, D; Sutanto, I; Tan, LK; Taylor, M | 1 |
4 review(s) available for piperaquine and primaquine
| Article | Year |
|---|---|
Using genetic methods to define the targets of compounds with antimalarial activity.
Topics: Animals; Anopheles; Antimalarials; Drug Resistance; Genetic Association Studies; Genome, Protozoan; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum | 2013 |
Current progress in antimalarial pharmacotherapy and multi-target drug discovery.
Topics: Animals; Antimalarials; Artemisinins; Drug Discovery; Drug Resistance; Humans; Malaria; Molecular Structure; Paclitaxel; Quinolines | 2020 |
Artemisinin-based combination therapy for treating uncomplicated Plasmodium vivax malaria.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Malaria, Vivax; Parasitemia; Primaquine; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Secondary Prevention; Sulfadoxine | 2013 |
The efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: A systematic review and individual patient data meta-analysis.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Humans; Malaria, Vivax; Plasmodium vivax; Primaquine; Quinolines; Recurrence; Risk; Treatment Outcome | 2019 |
21 trial(s) available for piperaquine and primaquine
| Article | Year |
|---|---|
CV8, a new combination of dihydroartemisinin, piperaquine, trimethoprim and primaquine, compared with atovaquone-proguanil against falciparum malaria in Vietnam.
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemisinins; Atovaquone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Parasitemia; Plasmodium falciparum; Primaquine; Proguanil; Quinolines; Sesquiterpenes; Treatment Outcome; Trimethoprim; Vietnam | 2004 |
Pharmacokinetics of piperaquine after repeated oral administration of the antimalarial combination CV8 in 12 healthy male subjects.
Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Chromatography, High Pressure Liquid; Drug Combinations; Fasting; Half-Life; Humans; Male; Middle Aged; Pilot Projects; Primaquine; Quinolines; Sesquiterpenes; Trimethoprim | 2006 |
Efficacy of Artequick versus artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria in Thailand.
Topics: Acute Disease; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Primaquine; Prospective Studies; Quinolines; Thailand; Treatment Outcome | 2008 |
Randomized, open-label trial of primaquine against vivax malaria relapse in Indonesia.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Drug Administration Schedule; Drug Dosage Calculations; Drug Resistance; Drug Therapy, Combination; Humans; Indonesia; Malaria; Malaria, Vivax; Male; Military Personnel; Plasmodium vivax; Primaquine; Quinine; Quinolines; Secondary Prevention | 2013 |
A randomized comparison of dihydroartemisinin-piperaquine and artesunate-amodiaquine combined with primaquine for radical treatment of vivax malaria in Sumatera, Indonesia.
Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; Humans; Indonesia; Kaplan-Meier Estimate; Malaria, Vivax; Male; Middle Aged; Plasmodium vivax; Primaquine; Prospective Studies; Quinolines; Treatment Outcome; Young Adult | 2013 |
Open-label crossover study of primaquine and dihydroartemisinin-piperaquine pharmacokinetics in healthy adult thai subjects.
Topics: Administration, Oral; Adult; Alanine Transaminase; Antimalarials; Area Under Curve; Artemisinins; Aspartate Aminotransferases; Biological Availability; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Primaquine; Quinolines; Thailand | 2014 |
The gametocytocidal efficacy of primaquine in malaria asymptomatic carriers treated with dihydroartemisinin-piperaquine in The Gambia (PRINOGAM): study protocol for a randomised controlled trial.
Topics: Antimalarials; Artemisinins; Clinical Protocols; Data Interpretation, Statistical; Drug Combinations; Humans; Plasmodium falciparum; Primaquine; Quinolines; Sample Size | 2015 |
Primaquine to reduce transmission of Plasmodium falciparum malaria in Mali: a single-blind, dose-ranging, adaptive randomised phase 2 trial.
Topics: Animals; Anopheles; Antimalarials; Artemisinins; Drug Administration Schedule; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mali; Primaquine; Quinolines; Single-Blind Method | 2016 |
The Gametocytocidal Efficacy of Different Single Doses of Primaquine with Dihydroartemisinin-piperaquine in Asymptomatic Parasite Carriers in The Gambia: A Randomized Controlled Trial.
Topics: Adolescent; Antimalarials; Artemisinins; Asymptomatic Diseases; Carrier State; Child; Drug Therapy, Combination; Female; Gambia; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Primaquine; Quinolines; Treatment Outcome | 2016 |
Population pharmacokinetics and electrocardiographic effects of dihydroartemisinin-piperaquine in healthy volunteers.
Topics: Adult; Antimalarials; Artemisinins; Computer Simulation; Cross-Over Studies; Drug Combinations; Drug Interactions; Electrocardiography; Healthy Volunteers; Heart Rate; Humans; Linear Models; Long QT Syndrome; Middle Aged; Models, Biological; Nonlinear Dynamics; Primaquine; Quinolines; Risk Assessment; Thailand; Young Adult | 2017 |
A Molecular Assay to Quantify Male and Female Plasmodium falciparum Gametocytes: Results From 2 Randomized Controlled Trials Using Primaquine for Gametocyte Clearance.
Topics: Adolescent; Antimalarials; Artemisinins; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Germ Cells; Humans; Kenya; Male; Mali; Plasmodium falciparum; Primaquine; Protozoan Proteins; Quinolines; RNA, Messenger; Sample Size | 2017 |
A controlled human malaria infection model enabling evaluation of transmission-blocking interventions.
Topics: Adamantane; Adolescent; Adult; Animals; Antimalarials; Culicidae; Erythrocytes; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Models, Biological; Peroxides; Plasmodium falciparum; Primaquine; Quinolines | 2018 |
Efficacy and safety of primaquine and methylene blue for prevention of Plasmodium falciparum transmission in Mali: a phase 2, single-blind, randomised controlled trial.
Topics: Adolescent; Adult; Amodiaquine; Artemisinins; Child; Child, Preschool; Drug Combinations; Humans; Malaria, Falciparum; Mali; Methylene Blue; Middle Aged; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinolines; Sulfadoxine; Young Adult | 2018 |
Enantiospecific pharmacokinetics and drug-drug interactions of primaquine and blood-stage antimalarial drugs.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Cross-Over Studies; Drug Interactions; Drug Therapy, Combination; Female; Healthy Volunteers; Humans; Malaria, Vivax; Male; Middle Aged; Primaquine; Quinolines; Thailand; Young Adult | 2018 |
Cluster-randomized trial of monthly malaria prophylaxis versus focused screening and treatment: a study protocol to define malaria elimination strategies in Cambodia.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Cambodia; Child; Child, Preschool; Disease Eradication; Drug Administration Schedule; Drug Combinations; Female; Humans; Insecticides; Malaria, Falciparum; Male; Mass Screening; Middle Aged; Military Medicine; Military Personnel; Mosquito Control; Pilot Projects; Plasmodium falciparum; Predictive Value of Tests; Primaquine; Protective Clothing; Quinolines; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome; Young Adult | 2018 |
A cluster randomised controlled trial of two rounds of mass drug administration in Zanzibar, a malaria pre-elimination setting-high coverage and safety, but no significant impact on transmission.
Topics: Antimalarials; Artemisinins; Female; Humans; Incidence; Malaria; Male; Mass Drug Administration; Prevalence; Primaquine; Quinolines; Tanzania | 2018 |
Chloroquine Versus Dihydroartemisinin-Piperaquine With Standard High-dose Primaquine Given Either for 7 Days or 14 Days in Plasmodium vivax Malaria.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Vivax; Male; Middle Aged; Myanmar; Primaquine; Quinolines; Recurrence; Thailand; Young Adult | 2019 |
The use of ultrasensitive quantitative-PCR to assess the impact of primaquine on asymptomatic relapse of Plasmodium vivax infections: a randomized, controlled trial in Lao PDR.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Asymptomatic Infections; Female; Humans; Laos; Malaria, Vivax; Male; Mass Drug Administration; Plasmodium vivax; Polymerase Chain Reaction; Primaquine; Quinolines; Recurrence; Time Factors; Young Adult | 2020 |
Mass drug administrations with dihydroartemisinin-piperaquine and single low dose primaquine to eliminate Plasmodium falciparum have only a transient impact on Plasmodium vivax: Findings from randomised controlled trials.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cambodia; Child; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Mass Drug Administration; Myanmar; Prevalence; Primaquine; Quinolines; Recurrence; Treatment Outcome; Vietnam; Young Adult | 2020 |
Mass drug administration for the acceleration of malaria elimination in a region of Myanmar with artemisinin-resistant falciparum malaria: a cluster-randomised trial.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Cluster Analysis; Disease Eradication; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mass Drug Administration; Myanmar; Primaquine; Quinolines; Young Adult | 2021 |
Tafenoquine co-administered with dihydroartemisinin-piperaquine for the radical cure of Plasmodium vivax malaria (INSPECTOR): a randomised, placebo-controlled, efficacy and safety study.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Therapy, Combination; Humans; Malaria; Malaria, Vivax; Plasmodium vivax; Primaquine; Quinolines | 2023 |
18 other study(ies) available for piperaquine and primaquine
| Article | Year |
|---|---|
In vitro chemosensitization of Plasmodium falciparum to antimalarials by verapamil and probenecid.
Topics: Adjuvants, Pharmaceutic; Animals; Antimalarials; Parasitic Sensitivity Tests; Plasmodium falciparum; Probenecid; Verapamil | 2009 |
Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials.
Topics: Acridones; Animals; Antimalarials; Disease Models, Animal; Drug Discovery; Hep G2 Cells; Humans; Malaria; Mice; Plasmodium; Species Specificity; Structure-Activity Relationship | 2019 |
Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials.
Topics: Acridones; Administration, Oral; Animals; Antimalarials; Cell Survival; Disease Models, Animal; Female; Half-Life; Hep G2 Cells; Humans; Life Cycle Stages; Malaria; Male; Mice; Mice, Inbred C57BL; Plasmodium falciparum; Structure-Activity Relationship | 2020 |
[Sensitivity of Plasmodium falciparum to piperaquine in Baoting County, Hainan Island].
Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; China; Drug Synergism; Gametogenesis; Humans; Malaria; Middle Aged; Plasmodium falciparum; Primaquine; Quinolines | 1985 |
Rapid and effective malaria control in Cambodia through mass administration of artemisinin-piperaquine.
Topics: Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Antimalarials; Artemisinins; Cambodia; Child; Drug Administration Schedule; Drug Therapy, Combination; Endemic Diseases; Female; Humans; Malaria, Falciparum; Male; Parasitemia; Pilot Projects; Plasmodium falciparum; Population Surveillance; Primaquine; Quinolines; Treatment Outcome | 2010 |
Mass campaigns with antimalarial drugs: a modelling comparison of artemether-lumefantrine and DHA-piperaquine with and without primaquine as tools for malaria control and elimination.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Models, Biological; Post-Exposure Prophylaxis; Prevalence; Primaquine; Quinolines; Young Adult; Zambia | 2015 |
In Vitro Activities of Primaquine-Schizonticide Combinations on Asexual Blood Stages and Gametocytes of Plasmodium falciparum.
Topics: Antimalarials; Benzothiazoles; Chloroquine; Diamines; Drug Combinations; Drug Interactions; Erythrocytes; Ethanolamines; Flow Cytometry; Fluorenes; Humans; Lumefantrine; Mefloquine; Organic Chemicals; Parasitic Sensitivity Tests; Plasmodium falciparum; Primaquine; Quinolines; Sporozoites; Trophozoites | 2015 |
[Malaria in the Comoros Archipelago in 2015: status after 15 years of fight].
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Comoros; Female; Humans; Incidence; Infant; Infection Control; Lactones; Malaria, Falciparum; Male; Plasmodium falciparum; Primaquine; Quinolines; Surveys and Questionnaires; Young Adult | 2016 |
The acceptability of mass administrations of anti-malarial drugs as part of targeted malaria elimination in villages along the Thai-Myanmar border.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Disease Eradication; Disease Transmission, Infectious; Female; Humans; Infant; Malaria; Male; Middle Aged; Myanmar; Patient Acceptance of Health Care; Pregnancy; Primaquine; Quinolines; Surveys and Questionnaires; Thailand; Young Adult | 2016 |
Unsupervised primaquine for the treatment of Plasmodium vivax malaria relapses in southern Papua: A hospital-based cohort study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Child; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Female; Humans; Indonesia; Infant; Malaria, Vivax; Male; Middle Aged; Primaquine; Quinolines; Recurrence; Retrospective Studies; Young Adult | 2017 |
The prevalence, incidence and prevention of Plasmodium falciparum infections in forest rangers in Bu Gia Map National Park, Binh Phuoc province, Vietnam: a pilot study.
Topics: Adult; Antibiotic Prophylaxis; Antimalarials; Artemisinins; Drug Therapy, Combination; Feasibility Studies; Humans; Incidence; Malaria, Falciparum; Male; Occupational Diseases; Parks, Recreational; Pilot Projects; Plasmodium falciparum; Prevalence; Primaquine; Quinolines; Vietnam | 2017 |
Closing in on the Reservoir: Proactive Case Detection in High-Risk Groups as a Strategy to Detect Plasmodium falciparum Asymptomatic Carriers in Cambodia.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cambodia; Carrier State; Child; Child, Preschool; Disease Reservoirs; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Pharmacy and Therapeutics Committee; Pilot Projects; Plasmodium falciparum; Primaquine; Quinolines; Risk Factors; Young Adult | 2018 |
Large-scale Artemisinin-Piperaquine Mass Drug Administration With or Without Primaquine Dramatically Reduces Malaria in a Highly Endemic Region of Africa.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Comoros; DNA, Protozoan; Drug Therapy, Combination; Endemic Diseases; Female; Humans; Infant; Malaria, Falciparum; Male; Mass Drug Administration; Parasitemia; Plasmodium falciparum; Polymorphism, Genetic; Primaquine; Quinolines; Treatment Outcome; Young Adult | 2018 |
[Diagnosis and Treatment of the First Imported Case of Plasmodium knowlesi Infection in China].
Topics: Animals; Antimalarials; Artemisinins; China; Chloroquine; Erythrocytes; Hemeproteins; Humans; Malaria; Microscopy; Plasmodium knowlesi; Polymerase Chain Reaction; Primaquine; Quinolines; Trophozoites | 2016 |
Safety, Pharmacokinetics, and Mosquito-Lethal Effects of Ivermectin in Combination With Dihydroartemisinin-Piperaquine and Primaquine in Healthy Adult Thai Subjects.
Topics: Adolescent; Adult; Animals; Anopheles; Antimalarials; Artemisinins; Drug Interactions; Drug Therapy, Combination; Female; Humans; Insecticides; Ivermectin; Malaria; Male; Middle Aged; Primaquine; Quinolines; Thailand; Young Adult | 2020 |
Liver Enzyme Elevations in
Topics: Acrylamides; Adamantane; Adult; Alanine Transaminase; Aminopyridines; Aminoquinolines; Antimalarials; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Erythrocyte Transfusion; Erythrocytes; Female; Ferrous Compounds; Healthy Volunteers; Heterocyclic Compounds, 4 or More Rings; Humans; Indoles; Isoquinolines; Malaria, Falciparum; Male; Metallocenes; Parasitemia; Peroxides; Piperazines; Plasmodium falciparum; Primaquine; Pyrimidines; Quinolines; Spiro Compounds; Sulfones; Triazoles; Young Adult | 2020 |
Prevalence of CYP2D6 Genotypes and Predicted Phenotypes in a Cohort of Cambodians at High Risk for Infections with
Topics: Antimalarials; Artemisinins; Asian People; Cambodia; Cytochrome P-450 CYP2D6; Drug Therapy, Combination; Endemic Diseases; Gene Frequency; Genotype; Humans; Malaria, Vivax; Pharmacogenomic Variants; Phenotype; Plasmodium vivax; Polymorphism, Genetic; Primaquine; Quinolines; Recurrence; Treatment Failure | 2020 |
Mechanistic Modeling of Primaquine Pharmacokinetics, Gametocytocidal Activity, and Mosquito Infectivity.
Topics: Animals; Antimalarials; Artemisinins; Culicidae; Drug Therapy, Combination; Humans; Malaria, Falciparum; Piperazines; Plasmodium falciparum; Primaquine; Quinolines | 2022 |