nnc 112 has been researched along with sch 23390 in 5 studies
| Studies (nnc 112) | Trials (nnc 112) | Recent Studies (post-2010) (nnc 112) | Studies (sch 23390) | Trials (sch 23390) | Recent Studies (post-2010) (sch 23390) |
|---|---|---|---|---|---|
| 32 | 3 | 7 | 803 | 0 | 585 |
| Protein | Taxonomy | nnc 112 (IC50) | sch 23390 (IC50) |
|---|---|---|---|
| D(2) dopamine receptor | Homo sapiens (human) | 1.0405 | |
| D | Rattus norvegicus (Norway rat) | 0.001 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.0461 | |
| D(1B) dopamine receptor | Homo sapiens (human) | 0.0011 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0006 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.3891 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bøgesø, K; Liljefors, T; Pettersson, I | 1 |
| Fujimura, Y; Ito, H; Kishimoto, T; Kosaka, J; Matsumoto, R; Nozaki, S; Okubo, Y; Suhara, T; Takahashi, H; Takano, A; Yasuno, F | 1 |
| Abi-Dargham, A; Girgis, RR; Poels, EM; Slifstein, M; Thompson, JL | 1 |
| Bang-Andersen, B; Christoffersen, CT; Farde, L; Finnema, SJ; Gulyás, B; Halldin, C; Jørgensen, M; Wikström, HV | 1 |
| Aisaborhale, E; Borra, RH; Granda, ML; Guimaraes, AR; Hooker, JM; Schauer, N; Schroeder, FA | 1 |
5 other study(ies) available for nnc 112 and sch 23390
| Article | Year |
|---|---|
Conformational analysis and structure-activity relationships of selective dopamine D-1 receptor agonists and antagonists of the benzazepine series.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Benzazepines; Chemical Phenomena; Chemistry, Physical; Dopamine Agents; Dopamine Antagonists; Molecular Conformation; Molecular Structure; Receptors, Dopamine; Receptors, Dopamine D1; Structure-Activity Relationship; Thermodynamics | 1990 |
Decreased binding of [11C]NNC112 and [11C]SCH23390 in patients with chronic schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzazepines; Benzofurans; Brain; Cerebral Cortex; Cognition; Corpus Striatum; Female; Humans; Ligands; Magnetic Resonance Imaging; Male; Middle Aged; Positron-Emission Tomography; Receptors, Dopamine D1; Schizophrenia | 2010 |
In vivo binding of the dopamine-1 receptor PET tracers [¹¹C]NNC112 and [¹¹C]SCH23390: a comparison study in individuals with schizophrenia.
Topics: Adolescent; Adult; Benzazepines; Benzofurans; Carbon Radioisotopes; Case-Control Studies; Female; Humans; Male; Positron-Emission Tomography; Radioactive Tracers; Radiopharmaceuticals; Receptors, Dopamine D1; Schizophrenia; Young Adult | 2013 |
The dopamine D₁ receptor agonist (S)-[¹¹C]N-methyl-NNC 01-0259 is not sensitive to changes in dopamine concentration--a positron emission tomography examination in the monkey brain.
Topics: Animals; Benzazepines; Benzofurans; Brain; CHO Cells; Cricetinae; Cricetulus; Dopamine; Dopamine Agonists; Humans; Macaca fascicularis; Positron-Emission Tomography; Protein Binding; Radiopharmaceuticals; Receptors, Dopamine D1 | 2013 |
First D1-like receptor PET imaging of the rat and primate kidney: implications for human disease monitoring.
Topics: Animals; Benzazepines; Benzofurans; Disease Models, Animal; Dopamine; Dopamine Antagonists; Kidney; Papio anubis; Positron-Emission Tomography; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Renin-Angiotensin System | 2014 |