mk 0663 has been researched along with mobic in 11 studies
| Studies (mk 0663) | Trials (mk 0663) | Recent Studies (post-2010) (mk 0663) | Studies (mobic) | Trials (mobic) | Recent Studies (post-2010) (mobic) |
|---|---|---|---|---|---|
| 549 | 173 | 265 | 1,739 | 396 | 936 |
| Protein | Taxonomy | mk 0663 (IC50) | mobic (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 1.5593 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.4364 | |
| Prostaglandin G/H synthase 2 | Mus musculus (house mouse) | 0.1514 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Byun, Y; Choi, JK; Choi, YH; Chung, S; Jeong, YS; Kim, JK; Kim, JY; Koh, HJ; Lee, KW; Lim, KM; Moh, JH; Noh, MS; Oh, YI; Park, YH; Shin, SS | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Hilário, MO; Len, CA; Terreri, MT | 1 |
| Abdalla, GK; Castro, EC; Faria, GE; Michelin, MA; Reis, MA; Silva, KT | 1 |
| Kasemier, J; Meek, IL; Movig, KL; van de Laar, MA; Vonkeman, HE | 1 |
| Blanca, M; Corzo, JL; Gallego, C; Mayorga, C; Muñoz, C; Requena, G; Torres, MJ; Urda, A; Zambonino, MA | 1 |
| Davydkin, IL; Zolotovskaya, IA | 1 |
| Davydkin, IL; Zolotovskaia, IA | 1 |
| Martínez, DM; Ramírez Zuluaga, LF; Rojas-Mejía, DV; Serrano Reyes, CD; Silva Espinosa, DL | 1 |
| Pedersen, L; Schmidt, M; Sørensen, HT | 1 |
1 review(s) available for mk 0663 and mobic
| Article | Year |
|---|---|
Nonsteroidal anti-inflammatory drugs: cyclooxygenase 2 inhibitors.
Topics: Adolescent; Aspirin; Celecoxib; Child; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Interactions; Etoricoxib; Fever; Humans; Hypersensitivity, Immediate; Inflammation; Leukotrienes; Meloxicam; Naproxen; Pain; Prostaglandins; Pyrazoles; Pyridines; Sulfonamides; Sulfones; Thiazines; Thiazoles; Treatment Outcome | 2006 |
2 trial(s) available for mk 0663 and mobic
| Article | Year |
|---|---|
Interference of NSAIDs with the thrombocyte inhibitory effect of aspirin: a placebo-controlled, ex vivo, serial placebo-controlled serial crossover study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Administration Schedule; Drug Interactions; Etoricoxib; Female; Humans; Ibuprofen; Male; Meloxicam; Middle Aged; Naproxen; Netherlands; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Pyridines; Risk Assessment; Sulfones; Thiazines; Thiazoles; Time Factors; Young Adult | 2013 |
[Effect of nonsteroidal anti-inflammatory drugs on the indicators of cardiovascular risk in patients with acute nonspecific back pain].
Topics: Acute Pain; Aged; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Female; Humans; Male; Meloxicam; Middle Aged; Pyridines; Sulfonamides; Sulfones; Thiazines; Thiazoles; Treatment Outcome | 2015 |
8 other study(ies) available for mk 0663 and mobic
| Article | Year |
|---|---|
In vitro structure-activity relationship and in vivo studies for a novel class of cyclooxygenase-2 inhibitors: 5-aryl-2,2-dialkyl-4-phenyl-3(2H)furanone derivatives.
Topics: Adult; Animals; Arthritis, Experimental; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Edema; Furans; Humans; In Vitro Techniques; Isoenzymes; Macrophages, Peritoneal; Male; Membrane Proteins; Mice; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Structure-Activity Relationship | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Trypanosoma cruzi: the role of PGE2 in immune response during the acute phase of experimental infection.
Topics: Acute Disease; Animals; Cells, Cultured; Chagas Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Etoricoxib; Fibrosis; Male; Meloxicam; Mice; Mice, Inbred BALB C; Myocardium; Parasitemia; Prostaglandins; Pyridines; Spleen; Sulfones; Thiazines; Thiazoles; Trypanosoma cruzi | 2008 |
Tolerance to COX-2 inhibitors in children with hypersensitivity to nonsteroidal anti-inflammatory drugs.
Topics: Adolescent; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Child; Cyclooxygenase 2 Inhibitors; Drug Hypersensitivity; Drug Substitution; Etoricoxib; Female; Humans; Male; Meloxicam; Pyridines; Retrospective Studies; Sulfones; Thiazines; Thiazoles; Urticaria | 2014 |
[Cognitive-cytokine effect of nonsteroidal antiinflammatory drugs in the therapy of elderly patients with osteoarthritis].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cognition; Cognition Disorders; Cytokines; Etoricoxib; Female; Humans; Interleukin-1beta; Interleukin-6; Male; Meloxicam; Osteoarthritis; Prospective Studies; Pyridines; Sulfonamides; Sulfones; Thiazines; Thiazoles; Transforming Growth Factor beta1 | 2017 |
Meloxicam and/or Etoricoxib Could Be Administered Safely in Two Equal Doses during an Open Oral Challenge in Patients with Nonsteroidal Anti-Inflammatory Drug Hypersensitivity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bronchial Provocation Tests; Cyclooxygenase 2 Inhibitors; Drug Hypersensitivity; Drug Substitution; Drug Therapy, Combination; Etoricoxib; Humans; Meloxicam | 2021 |
Cardiovascular Risks of Diclofenac Versus Other Older COX-2 Inhibitors (Meloxicam and Etodolac) and Newer COX-2 Inhibitors (Celecoxib and Etoricoxib): A Series of Nationwide Emulated Trials.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Etodolac; Etoricoxib; Female; Heart Disease Risk Factors; Humans; Meloxicam; Risk Factors | 2022 |