Page last updated: 2024-09-03

ly 134046 and yohimbine

ly 134046 has been researched along with yohimbine in 3 studies

Compound Research Comparison

Studies
(ly 134046)
Trials
(ly 134046)
Recent Studies (post-2010)
(ly 134046)
Studies
(yohimbine)
Trials
(yohimbine)
Recent Studies (post-2010) (yohimbine)
31005,893253532

Protein Interaction Comparison

ProteinTaxonomyly 134046 (IC50)yohimbine (IC50)
Alpha-2A adrenergic receptorHomo sapiens (human)0.0353
Cytochrome P450 2D6Homo sapiens (human)1.02
D(2) dopamine receptorHomo sapiens (human)2.06
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)1.3
Alpha-2B adrenergic receptorHomo sapiens (human)0.0428
Alpha-2C adrenergic receptorHomo sapiens (human)0.0466
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.126
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.0682
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.0682
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.0682
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)1.3
Alpha-1D adrenergic receptorHomo sapiens (human)1.013
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.126
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.074
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)1.3
5-hydroxytryptamine receptor 6Homo sapiens (human)1.689

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Crawley, JN; Hsiao, JK; Lawrenz, AL; Mefford, IN1
Ganong, WF; Steele, MK1
Guchhait, RB; Perry, BD; Stolk, JM; U'Prichard, DC; Vantini, G1

Other Studies

3 other study(ies) available for ly 134046 and yohimbine

ArticleYear
Activation in young rats induced by LY134046, an inhibitor of phenylethanolamine N-methyltransferase.
    Psychopharmacology, 1989, Volume: 98, Issue:2

    Topics: Animals; Benzazepines; Exploratory Behavior; Female; Male; Motor Activity; Phenylethanolamine N-Methyltransferase; Rats; Rats, Inbred Strains; Time Factors; Yohimbine

1989
Effects of catecholamine-depleting agents and receptor blockers on basal and angiotensin II- or norepinephrine-stimulated luteinizing hormone release in female rats.
    Endocrinology, 1986, Volume: 119, Issue:6

    Topics: Angiotensin II; Animals; Benzazepines; Catecholamines; Ditiocarb; Dopamine beta-Hydroxylase; Female; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Ovariectomy; Phenylethanolamine N-Methyltransferase; Prazosin; Propranolol; Rats; Saralasin; Yohimbine

1986
Assessment of the functional role of brain adrenergic neurons: chronic effects of phenylethanolamine N-methyltransferase inhibitors and alpha adrenergic receptor antagonists on brain norepinephrine metabolism.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Brain; Female; Isoquinolines; Norepinephrine; Phenylethanolamine N-Methyltransferase; Prazosin; Rats; Rats, Inbred F344; Tetrahydroisoquinolines; Tissue Distribution; Tyrosine 3-Monooxygenase; Yohimbine

1984