Page last updated: 2024-09-03

leo 271 f and estrone

leo 271 f has been researched along with estrone in 8 studies

Compound Research Comparison

Studies
(leo 271 f)
Trials
(leo 271 f)
Recent Studies (post-2010)
(leo 271 f)
Studies
(estrone)
Trials
(estrone)
Recent Studies (post-2010) (estrone)
80010,2664321,372

Protein Interaction Comparison

ProteinTaxonomyleo 271 f (IC50)estrone (IC50)
Estrogen receptorHomo sapiens (human)0.1261
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)6.589
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)0.4134
Sodium-dependent serotonin transporterHomo sapiens (human)5.301
Estrogen receptor betaHomo sapiens (human)0.3743
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)3

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's5 (62.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrell, HL; Duax, WL; Flocco, MM; Glusker, JP; Griffin, JF; Punzi, JS; Strong, P; Tew, KD; Zacharias, DE1
Andersson, SB; Ellman, M; Gunnarsson, PO; Sandberg, AA1
Andrén-Sandberg, A; Björk, P; Jönsson, U1
Andersson, SB; Björk, P; Fritjofsson, A; Gunnarsson, PO; Norlén, BJ1
Bergman, B; Daehlin, L; Damber, JE; Selstam, G1
Forshell, GP; Fritjofsson, A; Gunnarsson, PO; Norlén, BJ1
Bergenheim, AT; Edman, K; Gunnarsson, PO; Hariz, MI; Henriksson, R; von Schoultz, E1
Budman, DR; Kreis, W; Liu, XM; Wang, LG1

Other Studies

8 other study(ies) available for leo 271 f and estrone

ArticleYear
Molecular conformation of estramustine and two analogues.
    Molecular pharmacology, 1992, Volume: 41, Issue:3

    Topics: Estramustine; Estrone; Half-Life; Mechlorethamine; Molecular Conformation; Nitrogen Mustard Compounds; X-Ray Diffraction

1992
Accumulation of estramustine and estromustine in adipose tissue of rats and humans.
    Cancer chemotherapy and pharmacology, 1991, Volume: 28, Issue:5

    Topics: Adipose Tissue; Aged; Animals; Estramustine; Estrone; Female; Germ-Free Life; Humans; Liver; Male; Middle Aged; Muscles; Nitrogen Mustard Compounds; Pancreatic Neoplasms; Plasma; Preoperative Care; Rats; Rats, Inbred Strains; Time Factors

1991
Binding sites for the cytotoxic metabolites of estramustine phosphate (Estracyt) in rat and human pancreas that are distinct from pancreatic estrogen-binding protein.
    Pancreas, 1991, Volume: 6, Issue:1

    Topics: Aged; Animals; Binding Sites; Binding, Competitive; Carrier Proteins; Chemical Phenomena; Chemistry, Physical; Estradiol; Estramustine; Estrone; Female; Humans; Male; Middle Aged; Molecular Weight; Nitrogen Mustard Compounds; Pancreas; Pancreatic Neoplasms; Rats; Rats, Inbred Strains; Receptors, Estrogen

1991
Uptake of estramustine phosphate (estracyt) metabolites in prostatic cancer.
    The Journal of urology, 1988, Volume: 140, Issue:5

    Topics: Aged; Carcinoma; Carrier Proteins; Estradiol; Estramustine; Estrone; Humans; Male; Middle Aged; Nitrogen Mustard Compounds; Prostate; Prostatic Neoplasms; Prostatic Secretory Proteins

1988
Effects of human chorionic gonadotrophin, oestradiol and estromustine on testicular blood flow in hypophysectomized rats.
    International journal of andrology, 1985, Volume: 8, Issue:1

    Topics: Animals; Blood Pressure; Chorionic Gonadotropin; Endocrine Glands; Epididymis; Estradiol; Estrone; Humans; Hypophysectomy; Luteinizing Hormone; Male; Nitrogen Mustard Compounds; Prostate; Rats; Rats, Inbred Strains; Regional Blood Flow; Stimulation, Chemical; Testis

1985
Plasma concentrations of estramustine phosphate and its major metabolites in patients with prostatic carcinoma treated with different doses of estramustine phosphate (Estracyt).
    Scandinavian journal of urology and nephrology, 1981, Volume: 15, Issue:3

    Topics: Administration, Oral; Aged; Carcinoma; Estradiol; Estramustine; Estrone; Humans; Male; Middle Aged; Nitrogen Mustard Compounds; Prostatic Neoplasms; Time Factors

1981
Uptake and retention of estramustine and the presence of estramustine binding protein in malignant brain tumours in humans.
    British journal of cancer, 1993, Volume: 67, Issue:2

    Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Carrier Proteins; Ependymoma; Estramustine; Estrone; Female; Glioma; Humans; Immunohistochemistry; Male; Middle Aged; Nitrogen Mustard Compounds; Prostatic Secretory Proteins

1993
Androgen antagonistic effect of estramustine phosphate (EMP) metabolites on wild-type and mutated androgen receptor.
    Biochemical pharmacology, 1998, May-01, Volume: 55, Issue:9

    Topics: Androgen Antagonists; Antineoplastic Agents, Alkylating; Binding, Competitive; Estramustine; Estrogens; Estrone; Genes, Reporter; HeLa Cells; Humans; Kinetics; Luciferases; Male; Metribolone; Mutagenesis; Nitrogen Mustard Compounds; Prostatic Neoplasms; Receptors, Androgen; Recombinant Proteins; Transcriptional Activation; Transfection; Triamcinolone Acetonide; Tumor Cells, Cultured

1998