l 659066 and glyburide
l 659066 has been researched along with glyburide in 2 studies
Compound Research Comparison
| Studies (l 659066) | Trials (l 659066) | Recent Studies (post-2010) (l 659066) | Studies (glyburide) | Trials (glyburide) | Recent Studies (post-2010) (glyburide) |
|---|---|---|---|---|---|
| 79 | 40 | 57 | 6,554 | 620 | 1,344 |
Protein Interaction Comparison
| Protein | Taxonomy | l 659066 (IC50) | glyburide (IC50) |
|---|---|---|---|
| ATP-binding cassette sub-family C member 9 | Homo sapiens (human) | 0.22 | |
| Bile salt export pump | Rattus norvegicus (Norway rat) | 5.7 | |
| Bile salt export pump | Homo sapiens (human) | 5.5333 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 1.602 | |
| ATP-binding cassette sub-family C member 8 | Homo sapiens (human) | 0.0043 | |
| ATP-sensitive inward rectifier potassium channel 11 | Homo sapiens (human) | 0.1121 | |
| NACHT, LRR and PYD domains-containing protein 3 | Mus musculus (house mouse) | 10 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 1.8 |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Bastman, S; Chrusciel, P; Ranta-Panula, V; Ruohonen, ST; Scheinin, M; Streng, T | 1 |
| Bennett, RC; Kallio-Kujala, IJ; Meierjohann, A; Raekallio, MR; Savontaus, E; Scheinin, M; Spillmann, T; Vainio, OM; Yatkin, E | 1 |
Trials
1 trial(s) available for l 659066 and glyburide
| Article | Year |
|---|---|
Effects of dexmedetomidine and MK-467 on plasma glucose, insulin and glucagon in a glibenclamide-induced canine hypoglycaemia model.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Intravenous; Animals; Blood Glucose; Cross-Over Studies; Dexmedetomidine; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glucagon; Glyburide; Hypnotics and Sedatives; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Quinolizines; Random Allocation; Treatment Outcome | 2018 |
Other Studies
1 other study(ies) available for l 659066 and glyburide
| Article | Year |
|---|---|
Potentiation of Glibenclamide Hypoglycaemia in Mice by MK-467, a Peripherally Acting Alpha2-Adrenoceptor Antagonist.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Arterial Pressure; Biomarkers; Blood Glucose; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Glyburide; Heart Rate; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Medetomidine; Mice, Inbred C57BL; Quinolizines; Telemetry; Time Factors | 2015 |