Page last updated: 2024-09-03

icrf 198 and etoposide

icrf 198 has been researched along with etoposide in 2 studies

Compound Research Comparison

Studies (icrf 198)	Trials (icrf 198)	Recent Studies (post-2010) (icrf 198)	Studies (etoposide)	Trials (etoposide)	Recent Studies (post-2010) (etoposide)
24	0	4	18,306	3,693	4,900

Protein Interaction Comparison

Protein	Taxonomy	etoposide (IC50)
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	Homo sapiens (human)	1.153
nuclear receptor coactivator 3 isoform a	Homo sapiens (human)	1.4284
Polyunsaturated fatty acid lipoxygenase ALOX15	Oryctolagus cuniculus (rabbit)	3.187
Caspase-3	Homo sapiens (human)	1
DNA topoisomerase 2-beta	Homo sapiens (human)	0.4299
Solute carrier organic anion transporter family member 1B3	Homo sapiens (human)	4.18

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Allan, WP; Creighton, AM; Fattman, CL; Hasinoff, BB; Kuschak, TI; Thampatty, P; Yalowich, JC	1
Hasinoff, BB; Hofland, KF; Jensen, PB; Langer, SW; Schroeder, PE; Sehested, M	1

Other Studies

2 other study(ies) available for icrf 198 and etoposide

Article	Year
Characterization of a Chinese hamster ovary cell line with acquired resistance to the bisdioxopiperazine dexrazoxane (ICRF-187) catalytic inhibitor of topoisomerase II. Biochemical pharmacology, 1997, Jun-15, Volume: 53, Issue:12 Topics: Aclarubicin; Animals; CHO Cells; Cricetinae; DNA Topoisomerases, Type II; Drug Resistance; Ethylenediamines; Etoposide; Glycine; Mutation; Razoxane; Thiobarbiturates; Topoisomerase II Inhibitors; Verapamil	1997
Metabolism of dexrazoxane (ICRF-187) used as a rescue agent in cancer patients treated with high-dose etoposide. Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:2 Topics: Aged; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Ethylenediamines; Etoposide; Female; Glycine; Half-Life; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Razoxane	2003

Article

Year

Characterization of a Chinese hamster ovary cell line with acquired resistance to the bisdioxopiperazine dexrazoxane (ICRF-187) catalytic inhibitor of topoisomerase II.

Biochemical pharmacology, 1997, Jun-15, Volume: 53, Issue:12

Topics: Aclarubicin; Animals; CHO Cells; Cricetinae; DNA Topoisomerases, Type II; Drug Resistance; Ethylenediamines; Etoposide; Glycine; Mutation; Razoxane; Thiobarbiturates; Topoisomerase II Inhibitors; Verapamil

1997

Metabolism of dexrazoxane (ICRF-187) used as a rescue agent in cancer patients treated with high-dose etoposide.

Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:2

Topics: Aged; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Ethylenediamines; Etoposide; Female; Glycine; Half-Life; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Razoxane

2003