gastrodin and pilocarpine
gastrodin has been researched along with pilocarpine in 3 studies
Compound Research Comparison
| Studies (gastrodin) | Trials (gastrodin) | Recent Studies (post-2010) (gastrodin) | Studies (pilocarpine) | Trials (pilocarpine) | Recent Studies (post-2010) (pilocarpine) |
|---|---|---|---|---|---|
| 302 | 3 | 234 | 7,334 | 340 | 1,528 |
Protein Interaction Comparison
| Protein | Taxonomy | gastrodin (IC50) | pilocarpine (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 3.0267 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 3.84 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 3.84 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 3.84 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 3.84 |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Cao, XY; Hong, P; Ji, WG; Qi, AP; Shao, H; Yang, Y; Zhu, GX; Zhu, ZR | 1 |
| Chiu, SC; Huang, CW; Lai, MC; Liu, PY; Wu, SN; Yang, CS | 1 |
| Han, J; Li, Y; Wang, Y; Yang, Y | 1 |
Other Studies
3 other study(ies) available for gastrodin and pilocarpine
| Article | Year |
|---|---|
Gastrodin Reduces the Severity of Status Epilepticus in the Rat Pilocarpine Model of Temporal Lobe Epilepsy by Inhibiting Nav1.6 Sodium Currents.
Topics: Animals; Benzyl Alcohols; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Temporal Lobe; Glucosides; Male; NAV1.6 Voltage-Gated Sodium Channel; Pilocarpine; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Sodium Channel Blockers; Status Epilepticus | 2017 |
Gastrodin alleviates seizure severity and neuronal excitotoxicities in the rat lithium-pilocarpine model of temporal lobe epilepsy via enhancing GABAergic transmission.
Topics: Animals; Anticonvulsants; Benzyl Alcohols; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Gastrodia; Glucosides; Hippocampus; Lithium; Male; Medicine, Chinese Traditional; Neurons; Neuroprotective Agents; Pilocarpine; Rats, Sprague-Dawley; Receptors, GABA-A; Rhizome; Seizures; Status Epilepticus | 2021 |
Gastrodin attenuates lithium-pilocarpine-induced epilepsy by activating AMPK-mediated PPARα in a juvenile rat model.
Topics: Adenylate Kinase; Animals; Behavior, Animal; Benzyl Alcohols; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Electroencephalography; Enzyme Activation; Epilepsy; Glucosides; Lithium Compounds; Nerve Growth Factor; Pilocarpine; PPAR alpha; Rats; Rats, Sprague-Dawley; Signal Transduction | 2021 |