exp3174 and aldosterone
exp3174 has been researched along with aldosterone in 4 studies
Compound Research Comparison
| Studies (exp3174) | Trials (exp3174) | Recent Studies (post-2010) (exp3174) | Studies (aldosterone) | Trials (aldosterone) | Recent Studies (post-2010) (aldosterone) |
|---|---|---|---|---|---|
| 236 | 29 | 43 | 25,333 | 1,517 | 4,169 |
Protein Interaction Comparison
| Protein | Taxonomy | exp3174 (IC50) | aldosterone (IC50) |
|---|---|---|---|
| Mineralocorticoid receptor | Homo sapiens (human) | 0.0048 | |
| Mineralocorticoid receptor | Rattus norvegicus (Norway rat) | 0.043 |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Biollaz, J; Borland, RM; Brunner, HR; Christen, Y; Lee, RJ; Munafo, A; Nussberger, J; Shum, LY; Waeber, B | 1 |
| Chakravarty, PK; Chang, RS; Clineschmidt, BV; Greenlee, WJ; Lotti, VJ; Mantlo, NB; Patchett, AA; Siegl, PK | 1 |
| Chakravarty, PK; Chang, RS; Greenlee, WJ; Lotti, VJ; Mantlo, NB; Ondeyka, DL; Patchett, AA; Siegl, PK; Sweet, CS | 1 |
| Nakashima, M; Ohtawa, M; Saitoh, K; Takayama, F; Yoshinaga, T | 1 |
Trials
2 trial(s) available for exp3174 and aldosterone
| Article | Year |
|---|---|
Drug concentration response relationships in normal volunteers after oral administration of losartan, an angiotensin II receptor antagonist.
Topics: Administration, Oral; Adult; Aldosterone; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biotransformation; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Humans; Imidazoles; Losartan; Male; Reference Values; Renin; Tetrazoles | 1992 |
Pharmacokinetics and biochemical efficacy after single and multiple oral administration of losartan, an orally active nonpeptide angiotensin II receptor antagonist, in humans.
Topics: Administration, Oral; Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Heart Rate; Humans; Imidazoles; Losartan; Male; Middle Aged; Renin; Tetrazoles | 1993 |
Other Studies
2 other study(ies) available for exp3174 and aldosterone
| Article | Year |
|---|---|
In vitro pharmacology of L-158,809, a new highly potent and selective angiotensin II receptor antagonist.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Binding, Competitive; Biphenyl Compounds; Brain; Cell Membrane; Culture Techniques; Humans; Imidazoles; Losartan; Macaca mulatta; Muscle, Smooth, Vascular; Rabbits; Rats; Species Specificity; Tetrazoles | 1992 |
In vivo pharmacology of L-158,809, a new highly potent and selective nonpeptide angiotensin II receptor antagonist.
Topics: Administration, Oral; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Female; Imidazoles; Injections, Intravenous; Losartan; Macaca mulatta; Male; Pressoreceptors; Pyridines; Rats; Rats, Inbred Strains; Tetrazoles | 1992 |