em 139 has been researched along with estrone in 3 studies
| Studies (em 139) | Trials (em 139) | Recent Studies (post-2010) (em 139) | Studies (estrone) | Trials (estrone) | Recent Studies (post-2010) (estrone) |
|---|---|---|---|---|---|
| 12 | 0 | 0 | 10,266 | 432 | 1,372 |
| Protein | Taxonomy | em 139 (IC50) | estrone (IC50) |
|---|---|---|---|
| Estrogen receptor | Homo sapiens (human) | 0.1261 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 6.589 | |
| 17-beta-hydroxysteroid dehydrogenase type 1 | Homo sapiens (human) | 0.4134 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 5.301 | |
| Estrogen receptor beta | Homo sapiens (human) | 0.3743 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cadot, C; Fournier, MA; Laplante, Y; Poirier, D | 1 |
| de Launoit, Y; Dufour, M; Labrie, F; Simard, J; Veilleux, R | 1 |
| Labrie, C; Labrie, F; Lévesque, C; Li, S; Mérand, Y | 1 |
3 other study(ies) available for em 139 and estrone
| Article | Year |
|---|---|
Estradiol and estrone C-16 derivatives as inhibitors of type 1 17beta-hydroxysteroid dehydrogenase: blocking of ER+ breast cancer cell proliferation induced by estrone.
Topics: 17-Hydroxysteroid Dehydrogenases; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Estradiol; Estrone; Female; Humans; Receptors, Estrogen; Structure-Activity Relationship | 2008 |
Characteristics of the biphasic action of androgens and of the potent antiproliferative effects of the new pure antiestrogen EM-139 on cell cycle kinetic parameters in LNCaP human prostatic cancer cells.
Topics: Androgens; Androstane-3,17-diol; Binding, Competitive; Cell Cycle; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Antagonism; Estradiol; Estrogen Antagonists; Estrone; Flow Cytometry; Flutamide; Humans; In Vitro Techniques; Male; Metribolone; Piperidines; Prostatic Neoplasms; Raloxifene Hydrochloride; Tamoxifen; Testosterone; Time Factors; Tumor Cells, Cultured | 1991 |
Inhibitory effect of a steroidal antiestrogen (EM-170) on estrone-stimulated growth of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat.
Topics: 17-Hydroxysteroid Dehydrogenases; 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Estrogen Antagonists; Estrone; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1995 |