Page last updated: 2024-09-04

cyc 202 and sb 415286

cyc 202 has been researched along with sb 415286 in 7 studies

Compound Research Comparison

Studies
(cyc 202)
Trials
(cyc 202)
Recent Studies (post-2010)
(cyc 202)
Studies
(sb 415286)
Trials
(sb 415286)
Recent Studies (post-2010) (sb 415286)
9797393116052

Protein Interaction Comparison

ProteinTaxonomycyc 202 (IC50)sb 415286 (IC50)
Serine/threonine-protein kinase/endoribonuclease IRE1Homo sapiens (human)1.3
G2/mitotic-specific cyclin-B2Homo sapiens (human)0.9
Cyclin-dependent kinase 1Homo sapiens (human)0.9
G2/mitotic-specific cyclin-B1Homo sapiens (human)0.9
Cyclin-A2Homo sapiens (human)0.38
Cyclin-dependent kinase 2Homo sapiens (human)0.38
Glycogen synthase kinase-3 alphaHomo sapiens (human)0.104
Glycogen synthase kinase-3 betaHomo sapiens (human)0.1108
Cyclin-A1Homo sapiens (human)0.38
G2/mitotic-specific cyclin-B3Homo sapiens (human)0.9
large T antigenBetapolyomavirus macacae55.43

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Camins, A; Canudas, AM; Crespo-Biel, N; Gutiérrez-Cuesta, J; Melchiorri, D; Nicoletti, F; Pallàs, M1
Benfenati, F; Chami, M; Checler, F; Del Prete, D; Greco, B; Lauritzen, I; Moreno, S; Oulès, B; Paterlini-Bréchot, P; Sevalle, J; Trebak, M; Zhang, X1
Cwiklinski, E; Hoffmann, TM; Hundal, HS; Hyde, R; Lipina, C; Stretton, C; Taylor, PM1
Huang, Z; Li, H; Li, J; Li, Y; Liao, Z; Liu, Y; Miao, L; Xu, Y; Zhang, J1

Other Studies

7 other study(ies) available for cyc 202 and sb 415286

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Regulation of GSK-3beta by calpain in the 3-nitropropionic acid model.
    Hippocampus, 2010, Volume: 20, Issue:8

    Topics: Amino Acid Chloromethyl Ketones; Aminophenols; Animals; Calpain; Caspases; Cell Survival; Cells, Cultured; Convulsants; Disease Models, Animal; Embryo, Mammalian; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Male; Maleimides; Mice; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Nitro Compounds; Propionates; Purines; Rats; Roscovitine; Signal Transduction; Time Factors

2010
Ryanodine receptor blockade reduces amyloid-β load and memory impairments in Tg2576 mouse model of Alzheimer disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Aug-22, Volume: 32, Issue:34

    Topics: Alzheimer Disease; Aminophenols; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Animals; Brain; Caffeine; Calcium; Calcium Channel Blockers; Cells, Cultured; Cytosol; Dantrolene; Disease Models, Animal; Embryo, Mammalian; Endoplasmic Reticulum; Enzyme Inhibitors; Exploratory Behavior; Gene Expression Regulation; Humans; Inositol 1,4,5-Trisphosphate Receptors; Maleimides; Maze Learning; Membrane Potentials; Membrane Proteins; Memory Disorders; Mice; Mice, Transgenic; Muscle Relaxants, Central; Mutation; Nerve Tissue Proteins; Neuroblastoma; Neurons; Patch-Clamp Techniques; Peptide Fragments; Phosphorylation; Plaque, Amyloid; Purines; Reaction Time; Recognition, Psychology; RNA, Messenger; Roscovitine; Ryanodine Receptor Calcium Release Channel; Transfection

2012
CDK7 is a component of the integrated stress response regulating SNAT2 (SLC38A2)/System A adaptation in response to cellular amino acid deprivation.
    Biochimica et biophysica acta. Molecular cell research, 2019, Volume: 1866, Issue:6

    Topics: Activating Transcription Factor 4; Amino Acid Transport System A; Amino Acids; Aminophenols; Animals; Cell Line; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Flavonoids; HEK293 Cells; HeLa Cells; Humans; Maleimides; Phenylenediamines; Piperidines; Protein Serine-Threonine Kinases; Pyrimidines; Rats; Roscovitine; Stress, Physiological

2019
Regulation of CRMP2 by Cdk5 and GSK-3β participates in sevoflurane-induced dendritic development abnormalities and cognitive dysfunction in developing rats.
    Toxicology letters, 2021, May-01, Volume: 341

    Topics: Aminophenols; Animals; Cognitive Dysfunction; Cyclin-Dependent Kinase 5; Dendrites; Gene Expression Regulation, Developmental; Glycogen Synthase Kinase 3 beta; Hippocampus; Intercellular Signaling Peptides and Proteins; Maleimides; Nerve Tissue Proteins; Protein Kinase Inhibitors; Pyramidal Cells; Rats; Roscovitine; Sevoflurane

2021