Page last updated: 2024-09-04

cox 189 and estrone

cox 189 has been researched along with estrone in 3 studies

Compound Research Comparison

Studies (cox 189)	Trials (cox 189)	Recent Studies (post-2010) (cox 189)	Studies (estrone)	Trials (estrone)	Recent Studies (post-2010) (estrone)
163	49	47	10,266	432	1,372

Protein Interaction Comparison

Protein	Taxonomy	estrone (IC50)
Estrogen receptor	Homo sapiens (human)	0.1261
Polyunsaturated fatty acid lipoxygenase ALOX15	Oryctolagus cuniculus (rabbit)	6.589
17-beta-hydroxysteroid dehydrogenase type 1	Homo sapiens (human)	0.4134
Sodium-dependent serotonin transporter	Homo sapiens (human)	5.301
Estrogen receptor beta	Homo sapiens (human)	0.3743
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	3

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Honjo, H; Iwamoto, K; Uwai, Y	1

Reviews

1 review(s) available for cox 189 and estrone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

2 other study(ies) available for cox 189 and estrone

Article	Year
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Inhibitory effect of selective cyclooxygenase-2 inhibitor lumiracoxib on human organic anion transporters hOAT1 and hOAT3. Drug metabolism and pharmacokinetics, 2010, Volume: 25, Issue:5 Topics: Animals; Binding, Competitive; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Estrone; Etoricoxib; Humans; Inhibitory Concentration 50; Isoxazoles; Kinetics; Lactones; Methotrexate; Oocytes; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Pyrazoles; Pyridines; RNA, Complementary; Sulfonamides; Sulfones; Xenopus laevis	2010

Article

Year

A predictive ligand-based Bayesian model for human drug-induced liver injury.

Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010

Inhibitory effect of selective cyclooxygenase-2 inhibitor lumiracoxib on human organic anion transporters hOAT1 and hOAT3.

Drug metabolism and pharmacokinetics, 2010, Volume: 25, Issue:5

Topics: Animals; Binding, Competitive; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Estrone; Etoricoxib; Humans; Inhibitory Concentration 50; Isoxazoles; Kinetics; Lactones; Methotrexate; Oocytes; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Pyrazoles; Pyridines; RNA, Complementary; Sulfonamides; Sulfones; Xenopus laevis

2010