Page last updated: 2024-09-04

chs 828 and gne-617

chs 828 has been researched along with gne-617 in 3 studies

Compound Research Comparison

Studies
(chs 828)
Trials
(chs 828)
Recent Studies (post-2010)
(chs 828)
Studies
(gne-617)
Trials
(gne-617)
Recent Studies (post-2010) (gne-617)
2101714014

Protein Interaction Comparison

ProteinTaxonomychs 828 (IC50)gne-617 (IC50)
Cytochrome P450 1A2Homo sapiens (human)0.002
Cytochrome P450 3A4Homo sapiens (human)0.002
Cytochrome P450 2C9 Homo sapiens (human)0.002
Cytochrome P450 2C19Homo sapiens (human)0.002
Nicotinamide phosphoribosyltransferaseHomo sapiens (human)0.0044
Nicotinamide phosphoribosyltransferase Rattus norvegicus (Norway rat)0.023
Nicotinamide phosphoribosyltransferaseMus musculus (house mouse)0.024

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bair, KW; Bauer, P; Baumeister, T; Buckmelter, AJ; Caligiuri, M; Clodfelter, KH; Dragovich, PS; Gunzner-Toste, J; Han, B; Ho, YC; Kley, N; Liederer, BM; Lin, J; Ly, J; O'Brien, T; Oh, A; Reynolds, DJ; Sharma, G; Smith, CC; Wang, L; Wang, W; Wang, Z; Xiao, Y; Yuen, PW; Zak, M; Zhao, G; Zheng, X1
Chen, X; Dragovich, PS; Ho, YC; Liu, Y; Oh, A; Wang, W; Yuen, PW; Zak, M; Zheng, X1
Bair, KW; Dragovich, PS; Ho, YC; Hua, R; Liederer, BM; Liu, X; O'Brien, T; Oeh, J; Patel, S; Sampath, D; Skelton, N; Sodhi, J; Wang, W; Wang, Y; Xiao, Y; Yuen, PW; Zak, M; Zhang, L; Zhao, G; Zheng, X1

Other Studies

3 other study(ies) available for chs 828 and gne-617

ArticleYear
Structure-based discovery of novel amide-containing nicotinamide phosphoribosyltransferase (nampt) inhibitors.
    Journal of medicinal chemistry, 2013, Aug-22, Volume: 56, Issue:16

    Topics: Animals; Drug Discovery; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Mice; Mice, Nude; Models, Molecular; Molecular Structure; Nicotinamide Phosphoribosyltransferase; Spectrometry, Mass, Electrospray Ionization

2013
Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase.
    Chembiochem : a European journal of chemical biology, 2014, May-26, Volume: 15, Issue:8

    Topics: Animals; Antineoplastic Agents; Biocatalysis; Cell Line, Tumor; Cell Proliferation; Cytokines; Dogs; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Heterocyclic Compounds, 2-Ring; Humans; Models, Molecular; Molecular Structure; Nicotinamide Phosphoribosyltransferase; Permeability; Phosphoribosyl Pyrophosphate; Structure-Activity Relationship; Sulfones

2014
Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors.
    Journal of medicinal chemistry, 2016, 09-22, Volume: 59, Issue:18

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2C9 Inhibitors; Drug Discovery; Enzyme Inhibitors; Female; Humans; Mice; Mice, Nude; Models, Molecular; Neoplasms; Nicotinamide Phosphoribosyltransferase; Pyridines

2016