chs 828 has been researched along with gne-617 in 3 studies
| Studies (chs 828) | Trials (chs 828) | Recent Studies (post-2010) (chs 828) | Studies (gne-617) | Trials (gne-617) | Recent Studies (post-2010) (gne-617) |
|---|---|---|---|---|---|
| 21 | 0 | 17 | 14 | 0 | 14 |
| Protein | Taxonomy | chs 828 (IC50) | gne-617 (IC50) |
|---|---|---|---|
| Cytochrome P450 1A2 | Homo sapiens (human) | 0.002 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.002 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 0.002 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.002 | |
| Nicotinamide phosphoribosyltransferase | Homo sapiens (human) | 0.0044 | |
| Nicotinamide phosphoribosyltransferase | Rattus norvegicus (Norway rat) | 0.023 | |
| Nicotinamide phosphoribosyltransferase | Mus musculus (house mouse) | 0.024 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bair, KW; Bauer, P; Baumeister, T; Buckmelter, AJ; Caligiuri, M; Clodfelter, KH; Dragovich, PS; Gunzner-Toste, J; Han, B; Ho, YC; Kley, N; Liederer, BM; Lin, J; Ly, J; O'Brien, T; Oh, A; Reynolds, DJ; Sharma, G; Smith, CC; Wang, L; Wang, W; Wang, Z; Xiao, Y; Yuen, PW; Zak, M; Zhao, G; Zheng, X | 1 |
| Chen, X; Dragovich, PS; Ho, YC; Liu, Y; Oh, A; Wang, W; Yuen, PW; Zak, M; Zheng, X | 1 |
| Bair, KW; Dragovich, PS; Ho, YC; Hua, R; Liederer, BM; Liu, X; O'Brien, T; Oeh, J; Patel, S; Sampath, D; Skelton, N; Sodhi, J; Wang, W; Wang, Y; Xiao, Y; Yuen, PW; Zak, M; Zhang, L; Zhao, G; Zheng, X | 1 |
3 other study(ies) available for chs 828 and gne-617
| Article | Year |
|---|---|
Structure-based discovery of novel amide-containing nicotinamide phosphoribosyltransferase (nampt) inhibitors.
Topics: Animals; Drug Discovery; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Mice; Mice, Nude; Models, Molecular; Molecular Structure; Nicotinamide Phosphoribosyltransferase; Spectrometry, Mass, Electrospray Ionization | 2013 |
Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase.
Topics: Animals; Antineoplastic Agents; Biocatalysis; Cell Line, Tumor; Cell Proliferation; Cytokines; Dogs; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Heterocyclic Compounds, 2-Ring; Humans; Models, Molecular; Molecular Structure; Nicotinamide Phosphoribosyltransferase; Permeability; Phosphoribosyl Pyrophosphate; Structure-Activity Relationship; Sulfones | 2014 |
Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2C9 Inhibitors; Drug Discovery; Enzyme Inhibitors; Female; Humans; Mice; Mice, Nude; Models, Molecular; Neoplasms; Nicotinamide Phosphoribosyltransferase; Pyridines | 2016 |