Compounds > biotin
Page last updated: 2024-09-05

biotin and zidovudine

biotin has been researched along with zidovudine in 6 studies

Compound Research Comparison

Studies
(biotin)		Trials
(biotin)		Recent Studies (post-2010)
(biotin)		Studies
(zidovudine)		Trials
(zidovudine)		Recent Studies (post-2010) (zidovudine)
14,847953,88210,1801,3991,188

Protein Interaction Comparison

ProteinTaxonomybiotin (IC50)zidovudine (IC50)
Thymidine kinase, cytosolicHomo sapiens (human)3
Reverse transcriptase/RNaseH Human immunodeficiency virus 10.6633
Protease Human immunodeficiency virus 10.015

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Borchardt, RT; Chong, KT; Fisher, JF; Hui, JO; Islam, I; McQuade, TJ; Ng, KY; Rush, BD; Ruwart, MJ; Wilkinson, KF1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Buc, H; Buckle, M; Negroni, M; Williams, RM1
Bhuniya, S; Kim, BH; Park, SM1

Other Studies

6 other study(ies) available for biotin and zidovudine

ArticleYear
Evaluation of a vitamin-cloaking strategy for oligopeptide therapeutics: biotinylated HIV-1 protease inhibitors.
    Journal of medicinal chemistry, 1994, Jan-21, Volume: 37, Issue:2

    Topics: Animals; Biological Availability; Biotin; Drug Synergism; HIV Protease Inhibitors; HIV-1; Humans; Male; Rats; Rats, Sprague-Dawley; Receptors, Growth Factor; Tumor Cells, Cultured

1994
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Real time measurements of elongation by a reverse transcriptase using surface plasmon resonance.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Jan-23, Volume: 93, Issue:2

    Topics: Bacterial Proteins; Base Sequence; Biosensing Techniques; Biotin; Dideoxynucleotides; DNA; Molecular Sequence Data; Moloney murine leukemia virus; Nucleic Acid Heteroduplexes; Protein Binding; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Streptavidin; Thymine Nucleotides; Zidovudine

1996
Biotin-amino acid conjugates: an approach toward self-assembled hydrogelation.
    Organic letters, 2005, Apr-28, Volume: 7, Issue:9

    Topics: Amino Acids; Biotin; Drug Carriers; Hydrogels; Hydrogen-Ion Concentration; Microscopy, Electron, Scanning; Molecular Structure; Molecular Weight; Zidovudine

2005