biotin and pilocarpine
biotin has been researched along with pilocarpine in 9 studies
Compound Research Comparison
| Studies (biotin) | Trials (biotin) | Recent Studies (post-2010) (biotin) | Studies (pilocarpine) | Trials (pilocarpine) | Recent Studies (post-2010) (pilocarpine) |
|---|---|---|---|---|---|
| 14,847 | 95 | 3,882 | 7,334 | 340 | 1,528 |
Protein Interaction Comparison
| Protein | Taxonomy | biotin (IC50) | pilocarpine (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 3.0267 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 3.84 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 3.84 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 3.84 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 3.84 |
Research
Studies (9)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Goodman, JH; Scharfman, HE; Smith, KL; Sollas, AL | 1 |
| Berger, RE; Goodman, JH; Pierce, JP; Scharfman, HE; Sollas, AE | 1 |
| Draguhn, A; Hartmann, K; Schmitz, D; Stief, F; Zuschratter, W | 1 |
| Bassot, E; Boulland, JL; Bras, H; Chaudhry, FA; Coulon, P; Esclapez, M; Ferhat, L; Soussi, R; Storm-Mathisen, J | 1 |
| Chen, Z; Fang, Q; He, L; Liu, L; Liu, Z; Xu, Y; Zeng, C | 1 |
Other Studies
9 other study(ies) available for biotin and pilocarpine
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Survival of dentate hilar mossy cells after pilocarpine-induced seizures and their synchronized burst discharges with area CA3 pyramidal cells.
Topics: Action Potentials; Animals; Biotin; Cell Size; Cell Survival; Cortical Synchronization; Dendrites; Epilepsy, Temporal Lobe; Immunohistochemistry; Interneurons; Male; Mossy Fibers, Hippocampal; Muscarinic Agonists; Neural Pathways; Neuronal Plasticity; Neuropeptide Y; Pilocarpine; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus; Synaptic Transmission | 2001 |
Perforant path activation of ectopic granule cells that are born after pilocarpine-induced seizures.
Topics: Animals; Biotin; Cell Differentiation; Cell Movement; Choristoma; Dendrites; Dentate Gyrus; Electric Stimulation; Excitatory Postsynaptic Potentials; Male; Muscarinic Agonists; Neural Inhibition; Neurons; Organ Culture Techniques; Perforant Pathway; Pilocarpine; Rats; Rats, Sprague-Dawley; Reaction Time; Status Epilepticus; Stem Cells; Synaptic Transmission | 2003 |
Enhanced synaptic excitation-inhibition ratio in hippocampal interneurons of rats with temporal lobe epilepsy.
Topics: Animals; Biotin; Epilepsy, Temporal Lobe; Hippocampus; Interneurons; Male; Membrane Potentials; Muscarinic Agonists; Nerve Net; Neural Inhibition; Pilocarpine; Rats; Rats, Wistar; Synaptic Transmission | 2007 |
Reorganization of supramammillary-hippocampal pathways in the rat pilocarpine model of temporal lobe epilepsy: evidence for axon terminal sprouting.
Topics: Animals; Biotin; Dextrans; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Hypothalamus, Posterior; Male; Muscarinic Agonists; Neural Pathways; Phosphopyruvate Hydratase; Pilocarpine; Presynaptic Terminals; Rabies virus; Rats; Rats, Wistar; Vesicular Glutamate Transport Protein 2 | 2015 |
Dynorphin/KOR inhibits neuronal autophagy by activating mTOR signaling pathway to prevent acute seizure epilepsy.
Topics: Animals; Anticonvulsants; Apoptosis; Autophagy; Biotin; Dynorphins; Epilepsy; Green Fluorescent Proteins; Mammals; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; RNA, Messenger; Seizures; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2022 |