Page last updated: 2024-09-05

biotin and fluorouracil

biotin has been researched along with fluorouracil in 9 studies

Compound Research Comparison

Studies
(biotin)
Trials
(biotin)
Recent Studies (post-2010)
(biotin)
Studies
(fluorouracil)
Trials
(fluorouracil)
Recent Studies (post-2010) (fluorouracil)
14,847953,88245,5629,30714,663

Protein Interaction Comparison

ProteinTaxonomybiotin (IC50)fluorouracil (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.32
Thymidylate synthaseMus musculus (house mouse)1.58
AromataseHomo sapiens (human)0.63

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (77.78)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cao, SL; Jiang, W; Li, J; Li, YS; Li, Z; Liao, J; Peng, B; Ren, TT; Wang, FC; Wang, G; Wang, H; Xu, S; Xu, X; Yang, CR1
LITTMAN, ML; MIWATANI, T1
Hiep, HM; Tamiya, E; Yoshikawa, H1
Cheng, M; Liu, B; Ma, D; Zhi, K; Zhu, W1
Gao, X; Ji, Y; Jian, X; Li, Z; Liu, Z; Ni, W; Sun, S; Wu, L1
Das, H; Horo, H; Kundu, LM; Mandal, B; Saha, M1

Other Studies

9 other study(ies) available for biotin and fluorouracil

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Synthesis, cytotoxic evaluation and target identification of thieno[2,3-d]pyrimidine derivatives with a dithiocarbamate side chain at C2 position.
    European journal of medicinal chemistry, 2018, Jun-25, Volume: 154

    Topics: Antineoplastic Agents; Cell Cycle; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pyrimidines; Structure-Activity Relationship; Thiocarbamates; Tumor Cells, Cultured

2018
EFFECT OF WATER SOLUBLE VITAMINS AND THEIR ANALOGUES ON THE GROWTH OF CANDIDA ALBICANS. I. BIOTIN, PYRIDOXAMINE, PYRIDOXINE AND FLUORINATED PYRIMIDINES.
    Mycopathologia et mycologia applicata, 1963, Dec-15, Volume: 21

    Topics: Amines; Ascorbic Acid; Biotin; Candida; Candida albicans; Culture Media; Floxuridine; Fluorouracil; Folic Acid; Metabolism; Pharmacology; Pyridoxamine; Pyridoxine; Pyrimidines; Research; Vitamin B 12; Vitamin B Complex; Vitamins

1963
Interference localized surface plasmon resonance nanosensor tailored for the detection of specific biomolecular interactions.
    Analytical chemistry, 2010, Feb-15, Volume: 82, Issue:4

    Topics: Aluminum Oxide; Animals; Antibodies; Antibody Specificity; Avidin; Biotin; Cattle; Fluorouracil; Gold; Immunoassay; Metal Nanoparticles; Nanotechnology; Porosity; Protein Binding; Reproducibility of Results; Substrate Specificity; Surface Plasmon Resonance

2010
Synthesis of Biotin-Modified Galactosylated Chitosan Nanoparticles and Their Characteristics in Vitro and in Vivo.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 50, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Biotin; Cell Line; Cell Movement; Cell Proliferation; Chitosan; Drug Carriers; Fluorouracil; Galactose; Humans; Liver; Liver Neoplasms; Magnetic Resonance Spectroscopy; Mice; Nanoparticles; Optical Imaging; Particle Size; Spectroscopy, Fourier Transform Infrared

2018
Dual-Targeting Nanoparticles: Codelivery of Curcumin and 5-Fluorouracil for Synergistic Treatment of Hepatocarcinoma.
    Journal of pharmaceutical sciences, 2019, Volume: 108, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biotin; Carcinoma, Hepatocellular; Curcumin; Disaccharides; Drug Carriers; Drug Liberation; Drug Synergism; Fluorouracil; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Nanoparticles; Polyethylene Glycols; Polyglactin 910; Tissue Distribution; Xenograft Model Antitumor Assays

2019
Synthesis of highly fluorescent, amine-functionalized carbon dots from biotin-modified chitosan and silk-fibroin blend for target-specific delivery of antitumor agents.
    Carbohydrate polymers, 2022, Feb-01, Volume: 277

    Topics: Amines; Antimetabolites, Antineoplastic; Biotin; Carbon; Cell Proliferation; Cell Survival; Cells, Cultured; Chitosan; Drug Delivery Systems; Drug Liberation; Drug Screening Assays, Antitumor; Fibroins; Fluorescence; Fluorouracil; Humans; Molecular Structure; Optical Imaging; Particle Size; Quantum Dots; Spectrometry, Fluorescence

2022