biotin and fluorouracil
biotin has been researched along with fluorouracil in 9 studies
Compound Research Comparison
| Studies (biotin) | Trials (biotin) | Recent Studies (post-2010) (biotin) | Studies (fluorouracil) | Trials (fluorouracil) | Recent Studies (post-2010) (fluorouracil) |
|---|---|---|---|---|---|
| 14,847 | 95 | 3,882 | 45,562 | 9,307 | 14,663 |
Protein Interaction Comparison
| Protein | Taxonomy | biotin (IC50) | fluorouracil (IC50) |
|---|---|---|---|
| Epidermal growth factor receptor | Homo sapiens (human) | 0.32 | |
| Thymidylate synthase | Mus musculus (house mouse) | 1.58 | |
| Aromatase | Homo sapiens (human) | 0.63 |
Research
Studies (9)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Cao, SL; Jiang, W; Li, J; Li, YS; Li, Z; Liao, J; Peng, B; Ren, TT; Wang, FC; Wang, G; Wang, H; Xu, S; Xu, X; Yang, CR | 1 |
| LITTMAN, ML; MIWATANI, T | 1 |
| Hiep, HM; Tamiya, E; Yoshikawa, H | 1 |
| Cheng, M; Liu, B; Ma, D; Zhi, K; Zhu, W | 1 |
| Gao, X; Ji, Y; Jian, X; Li, Z; Liu, Z; Ni, W; Sun, S; Wu, L | 1 |
| Das, H; Horo, H; Kundu, LM; Mandal, B; Saha, M | 1 |
Other Studies
9 other study(ies) available for biotin and fluorouracil
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Synthesis, cytotoxic evaluation and target identification of thieno[2,3-d]pyrimidine derivatives with a dithiocarbamate side chain at C2 position.
Topics: Antineoplastic Agents; Cell Cycle; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pyrimidines; Structure-Activity Relationship; Thiocarbamates; Tumor Cells, Cultured | 2018 |
EFFECT OF WATER SOLUBLE VITAMINS AND THEIR ANALOGUES ON THE GROWTH OF CANDIDA ALBICANS. I. BIOTIN, PYRIDOXAMINE, PYRIDOXINE AND FLUORINATED PYRIMIDINES.
Topics: Amines; Ascorbic Acid; Biotin; Candida; Candida albicans; Culture Media; Floxuridine; Fluorouracil; Folic Acid; Metabolism; Pharmacology; Pyridoxamine; Pyridoxine; Pyrimidines; Research; Vitamin B 12; Vitamin B Complex; Vitamins | 1963 |
Interference localized surface plasmon resonance nanosensor tailored for the detection of specific biomolecular interactions.
Topics: Aluminum Oxide; Animals; Antibodies; Antibody Specificity; Avidin; Biotin; Cattle; Fluorouracil; Gold; Immunoassay; Metal Nanoparticles; Nanotechnology; Porosity; Protein Binding; Reproducibility of Results; Substrate Specificity; Surface Plasmon Resonance | 2010 |
Synthesis of Biotin-Modified Galactosylated Chitosan Nanoparticles and Their Characteristics in Vitro and in Vivo.
Topics: Animals; Antimetabolites, Antineoplastic; Biotin; Cell Line; Cell Movement; Cell Proliferation; Chitosan; Drug Carriers; Fluorouracil; Galactose; Humans; Liver; Liver Neoplasms; Magnetic Resonance Spectroscopy; Mice; Nanoparticles; Optical Imaging; Particle Size; Spectroscopy, Fourier Transform Infrared | 2018 |
Dual-Targeting Nanoparticles: Codelivery of Curcumin and 5-Fluorouracil for Synergistic Treatment of Hepatocarcinoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biotin; Carcinoma, Hepatocellular; Curcumin; Disaccharides; Drug Carriers; Drug Liberation; Drug Synergism; Fluorouracil; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Nanoparticles; Polyethylene Glycols; Polyglactin 910; Tissue Distribution; Xenograft Model Antitumor Assays | 2019 |
Synthesis of highly fluorescent, amine-functionalized carbon dots from biotin-modified chitosan and silk-fibroin blend for target-specific delivery of antitumor agents.
Topics: Amines; Antimetabolites, Antineoplastic; Biotin; Carbon; Cell Proliferation; Cell Survival; Cells, Cultured; Chitosan; Drug Delivery Systems; Drug Liberation; Drug Screening Assays, Antitumor; Fibroins; Fluorescence; Fluorouracil; Humans; Molecular Structure; Optical Imaging; Particle Size; Quantum Dots; Spectrometry, Fluorescence | 2022 |