Page last updated: 2024-09-05

atropine and emetine

atropine has been researched along with emetine in 15 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(emetine)
Trials
(emetine)
Recent Studies (post-2010) (emetine)
26,7111,2591,6971,79724162

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)emetine (IC50)
Glucose transporterLeishmania mexicana0.081
Serine hydrolase RBBP9Homo sapiens (human)7.8
Hexose transporter 1 Plasmodium falciparum (malaria parasite P. falciparum)0.09
ATP-dependent translocase ABCB1Homo sapiens (human)7.0667
Alpha-2A adrenergic receptorHomo sapiens (human)0.038
Solute carrier family 2, facilitated glucose transporter member 1Homo sapiens (human)0.108
Alpha-2C adrenergic receptorHomo sapiens (human)0.182
Hypoxia-inducible factor 1-alphaHomo sapiens (human)0.0965
Endothelial PAS domain-containing protein 1Homo sapiens (human)0.0965

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19907 (46.67)18.7374
1990's1 (6.67)18.2507
2000's2 (13.33)29.6817
2010's5 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Durotoye, AO; Salako, LA1
Di Giacomo, S; Imperatore, A; Marmo, E1
Molinengo, L2
Ng, KK1
Abe, Y; Kuroiwa, Y; Misawa, M; Takeda, H; Yanaura, S1
Combs, AB; Pan, SJ1
HADIDIAN, L; KOUSSA, M; SCHWABE, CW1
Gerszten, RE; Jin, S; Jin, YN; Kokel, D; Liu, Y; Macrae, CA; Peterson, RT; Roberts, LD; Sarkar, KS; Van Ham, TJ1

Other Studies

15 other study(ies) available for atropine and emetine

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effect of dehydroemetine on myocardial circulation and contractility in vivo.
    European journal of pharmacology, 1973, Volume: 23, Issue:1

    Topics: Animals; Atropine; Blood Pressure; Cats; Coronary Circulation; Electrocardiography; Emetine; Female; Heart; Heart Rate; Heart Ventricles; Male; Propranolol; Vagotomy; Vascular Resistance

1973
[Behavior of the electrocardiogram of normal rats and of rats pretreated with various drugs and then perfused with metochlopramid].
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:4

    Topics: Amides; Animals; Atropine; Benzoates; Electrocardiography; Emetine; Heart; Hexamethonium Compounds; Perfusion; Rats; Reserpine; Sympatholytics

1969
On the pharmacological inhibition of epinephrine-induced ventricular automaticity.
    European journal of pharmacology, 1968, Volume: 5, Issue:1

    Topics: Acetanilides; Acetylcholine; Animals; Atropine; Benzoates; Emetine; Ephedrine; Epinephrine; Heart; Heart Ventricles; In Vitro Techniques; Male; Methanol; Muscle Contraction; Muscle, Smooth; Procainamide; Quinacrine; Quinidine; Rats; Secologanin Tryptamine Alkaloids; Solubility; Sympatholytics; Urethane; Ventricular Fibrillation

1968
Blockade of adrenergic and cholinergic transmissions by emetine.
    British journal of pharmacology and chemotherapy, 1966, Volume: 28, Issue:2

    Topics: Acetylcholine; Amphetamine; Animals; Anura; Atropine; Cats; Cocaine; Colon; Diaphragm; Dopamine; Drug Antagonism; Drug Synergism; Electric Stimulation; Electrophysiology; Emetine; Ganglia; Gastrointestinal Motility; Guinea Pigs; Hexamethonium Compounds; Ileum; In Vitro Techniques; Neuromuscular Junction; Neurons; Nicotine; Nictitating Membrane; Norepinephrine; Phrenic Nerve; Physostigmine; Rabbits; Rats; Scopolamine; Sympathetic Nervous System

1966
The role of vagal reflex in mechanism of secretagogic action of bromhexine.
    Japanese journal of pharmacology, 1984, Volume: 35, Issue:4

    Topics: Animals; Atropine; Bromhexine; Dogs; Emetine; Exocrine Glands; Histocytochemistry; Male; Mucous Membrane; Reflex; Time Factors; Trachea; Vagotomy; Vagus Nerve

1984
Effects of pharmacological interventions on emetine cardiotoxicity in isolated perfused rat hearts.
    Toxicology, 1995, Mar-31, Volume: 97, Issue:1-3

    Topics: Animals; Atropine; Coronary Circulation; Electrocardiography; Emetine; Fructosediphosphates; Heart; L-Lactate Dehydrogenase; Male; Perfusion; Rats; Rats, Sprague-Dawley; Razoxane

1995
[On the applicability of Ferguson's principle and of the "sieve theory" to compounds with negative inotropic action].
    Archives internationales de pharmacodynamie et de therapie, 1963, May-01, Volume: 143

    Topics: Acetanilides; Alcohols; Alkaloids; Amides; Atropine; Dioxanes; Emetine; Ephedrine; Heart; Procainamide; Quinidine; Urethane

1963
HOST-PARASITE RELATIONSHIPS IN ECHINOCOCCOSIS. IX. IN VITRO SURVIVAL OF HYDATID SCOLICES AND THE EFFECTS OF DRUGS UPON SCOLEX RESPIRATION.
    The American journal of tropical medicine and hygiene, 1963, Volume: 12

    Topics: Acridines; Animals; Anti-Bacterial Agents; Antimony; Atropine; Culture Media; Diethylcarbamazine; Echinococcosis; Echinococcus; Emetine; Gentian Violet; Host-Parasite Interactions; In Vitro Techniques; Metabolism; Oxytetracycline; Physostigmine; Research; Temperature; Tetracycline

1963
An in vivo zebrafish screen identifies organophosphate antidotes with diverse mechanisms of action.
    Journal of biomolecular screening, 2013, Volume: 18, Issue:1

    Topics: Animals; Antidotes; Atropine; Cell Line, Tumor; Cholinergic Antagonists; Cholinesterase Reactivators; Drug Evaluation, Preclinical; Emetine; Glycopyrrolate; High-Throughput Screening Assays; Humans; Lethal Dose 50; Metoclopramide; Neostigmine; Organophosphates; Parathion; Pirenzepine; Pralidoxime Compounds; Zebrafish

2013