aj 76 and spiperone
aj 76 has been researched along with spiperone in 4 studies
Compound Research Comparison
| Studies (aj 76) | Trials (aj 76) | Recent Studies (post-2010) (aj 76) | Studies (spiperone) | Trials (spiperone) | Recent Studies (post-2010) (spiperone) |
|---|---|---|---|---|---|
| 37 | 0 | 2 | 2,944 | 13 | 85 |
Protein Interaction Comparison
| Protein | Taxonomy | aj 76 (IC50) | spiperone (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0008 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| D(4) dopamine receptor | Homo sapiens (human) | 0.0005 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | 0.097 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.0635 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0001 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.955 |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Bouthenet, ML; Giros, B; Martres, MP; Schwartz, JC; Sokoloff, P | 1 |
| Bervoets, K; Brocco, M; Dacquet, C; Girardon, S; Gobert, A; Millan, MJ; Newman-Tancredi, A; Peglion, JL; Rivet, JM; Vian, J | 1 |
| Fang, X; Hu, Z; Levant, B; Min, J; Varady, J; Wang, S; Wu, X | 1 |
| Gainetdinov, RR; Grekhova, TV; Rayevsky, KS; Sotnikova, TD | 1 |
Other Studies
4 other study(ies) available for aj 76 and spiperone
| Article | Year |
|---|---|
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics.
Topics: Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line; Cloning, Molecular; Cricetinae; DNA; DNA Restriction Enzymes; Dopamine; Guanylyl Imidodiphosphate; Molecular Sequence Data; Nucleic Acid Hybridization; Polymerase Chain Reaction; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Sequence Homology, Nucleic Acid; Tissue Distribution | 1990 |
Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: 1. Activation of postsynaptic D3 receptors mediates hypothermia, whereas blockade of D2 receptors elicits prolactin
Topics: 2-Naphthylamine; Animals; Body Temperature Regulation; Catalepsy; CHO Cells; Cricetinae; Dopamine Antagonists; Furans; Humans; Male; Prolactin; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Dopamine D2; Recombinant Proteins; Stereoisomerism | 1995 |
Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach.
Topics: Algorithms; Binding Sites; Computational Biology; Crystallography, X-Ray; Databases, Protein; Humans; Kinetics; Ligands; Lipid Bilayers; Models, Molecular; Molecular Conformation; Mutation; Receptors, Dopamine D2; Receptors, Dopamine D3; Reproducibility of Results; Solvents; Structure-Activity Relationship; Tetrahydronaphthalenes; Water | 2003 |
Effects of intrastriatal infusion of D2 and D3 dopamine receptor preferring antagonists on dopamine release in rat dorsal striatum (in vivo microdialysis study).
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Clozapine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Male; Microdialysis; Rats; Rats, Wistar; Receptors, Dopamine D3; Spiperone; Tetrahydronaphthalenes | 2001 |