a 2545 has been researched along with mexiletine in 3 studies
| Studies (a 2545) | Trials (a 2545) | Recent Studies (post-2010) (a 2545) | Studies (mexiletine) | Trials (mexiletine) | Recent Studies (post-2010) (mexiletine) |
|---|---|---|---|---|---|
| 9 | 1 | 0 | 1,488 | 210 | 227 |
| Protein | Taxonomy | a 2545 (IC50) | mexiletine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 1.138 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 10 | |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | 3 | |
| Sodium channel protein type 2 subunit alpha | Homo sapiens (human) | 2.9 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bódi, I; Frank, L; Hankovszky, OH; Hideg, K | 1 |
| Arita, J; Aye, NN; Hashimoto, K; Xue, YX | 1 |
| Alexy, T; Battyany, I; Halmosi, R; Hideg, K; Horvath, B; Kesmarky, G; Marton, Z; Toth, K; Vekasi, J | 1 |
3 other study(ies) available for a 2545 and mexiletine
| Article | Year |
|---|---|
New antiarrhythmic agents. 2,2,5,5-Tetramethyl-3-pyrroline-3-carboxamides and 2,2,5,5-tetramethylpyrrolidine-3-carboxamindes.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Evaluation, Preclinical; Indicators and Reagents; Magnetic Resonance Spectroscopy; Nicotine; Ouabain; Rats; Spectrophotometry, Infrared; Structure-Activity Relationship | 1986 |
Effects of an antiarrhythmic drug A-2545 on canine ventricular arrhythmia models; comparison with mexiletine and flecainide.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Electrocardiography; Flecainide; Heart Rate; Mexiletine; Models, Biological; Molecular Structure; Pyrroles | 1998 |
Scavenger effect of experimental and clinically used cardiovascular drugs.
Topics: Anti-Arrhythmia Agents; Antioxidants; Carbazoles; Cardiovascular Agents; Carvedilol; Erythrocytes; Free Radical Scavengers; Humans; Indoles; Male; Methylphenazonium Methosulfate; Mexiletine; Propanolamines; Pyrroles; Sotalol | 2001 |