Tick-borne flavivirus infection occurring in the Kyasanur Forest in India.
Synonym |
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Kyasanur Forest Disease Virus Infection |
Kyasanur Forest Disease |
Excerpt | Reference |
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"Kyasanur forest disease is a neglected zoonotic disease caused by a single-stranded RNA-based flavivirus, the incidence of which was first recorded in 1957 in the Southern part of India." | ( Jagannath, DK; Lakshminarasimhan, A; Malik, M; Mishra, RK; Vijayan, P, 2023) |
"Kyasanur forest disease is a neglected zoonotic disease caused by a single-stranded RNA-based flavivirus, the incidence of which was first recorded in 1957 in the Southern part of India." | ( Jagannath, DK; Lakshminarasimhan, A; Malik, M; Mishra, RK; Vijayan, P, 2023) |
"Kyasanur Forest Disease is a tick-borne flavivirus is endemic in the Southern India." | ( Dash, PK; Dhankher, S; Kiran, SK; Sharma, S; V K, S; Yadav, P, 2023) |
Timeframe | Studies, This Condition (%) | All Conditions % |
---|---|---|
pre-1990 | 10 (16.13) | 23.3326 |
1990's | 1 (1.61) | 12.5806 |
2000's | 1 (1.61) | 18.1394 |
2010's | 25 (40.32) | 28.8240 |
2020's | 25 (40.32) | 9.53 |
Drug | Indicated | Relationship Strength | Studies | Trials |
---|---|---|---|---|
interleukin-8 | 0 | low | 1 | 0 |
sofosbuvir | 0 | low | 2 | 0 |
abt-333 | 0 | low | 2 | 0 |
Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
---|---|---|---|---|
Spike glycoprotein | 1 | 0 | 0 | 1 |
RNA-directed RNA polymerase | 0 | 0 | 2 | 3 |
Protein cereblon | 0 | 3 | 0 | 3 |
NS5 | 0 | 0 | 1 | 1 |
Cereblon isoform 4 | 0 | 1 | 0 | 1 |
Cytochrome P450 1A2 | 0 | 1 | 0 | 1 |
Cytochrome P450 3A4 | 0 | 1 | 0 | 1 |
Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
Cytochrome P450 2C9 | 0 | 1 | 1 | 2 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |