Page last updated: 2024-12-11

revexepride

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

revexepride: 5-HT4 agonist for treatment of gastro-oesophageal reflux disease [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9823762
CHEMBL ID3545035
SCHEMBL ID505587
MeSH IDM000608700

Synonyms (24)

Synonym
8c63r2y02m ,
revexepride
219984-49-3
ssp-002358
revexepride [inn]
unii-8c63r2y02m
7-benzofurancarboxamide, 4-amino-5-chloro-2,3-dihydro-n-(((3s,4s)-3-hydroxy-1-(3-methoxypropyl)-4-piperidinyl)methyl)-2,2-dimethyl-
spd-557
(-)-revexepride
4-amino-5-chloro-n-(((3s,4s)-3-hydroxy-1-(3-methoxypropyl)piperidin-4-yl)methyl(-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-carboxamide
r149402 ,
7-benzofurancarboxamide, 4-amino-5-chloro-2,3-dihydro-n-(((3r,4r)-3-hydroxy-1-(3-methoxypropyl)-4-piperidinyl)methyl)-2,2-dimethyl-
r-149402
SCHEMBL505587
DTXSID30176429
CHEMBL3545035
spd557
HY-U00373
CS-7441
4-amino-5-chloro-n-(((3s,4s)-3-hydroxy-1-(3-methoxypropyl)piperidin-4-yl)methyl)-2,2-dimethyl-2,3-dihydrobenzofuran-7-carboxamide
4-amino-5-chloro-n-[[(3s,4s)-3-hydroxy-1-(3-methoxypropyl)piperidin-4-yl]methyl]-2,2-dimethyl-3h-1-benzofuran-7-carboxamide
Q27270174
MS-27512
AKOS040742543

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" Pharmacokinetic parameters were assessed for up to 48 hours after administration of the investigational product."( A phase 1 randomized study evaluating the effect of omeprazole on the pharmacokinetics of a novel 5-hydroxytryptamine receptor 4 agonist, revexepride (SSP-002358), in healthy adults.
Corcoran, M; Hoppenbrouwers, M; Hossack, S; Martin, P; Pierce, D; Velinova, M, 2015
)
0.62
" The pharmacokinetic parameters of revexepride were similar without or with omeprazole co-administration."( A phase 1 randomized study evaluating the effect of omeprazole on the pharmacokinetics of a novel 5-hydroxytryptamine receptor 4 agonist, revexepride (SSP-002358), in healthy adults.
Corcoran, M; Hoppenbrouwers, M; Hossack, S; Martin, P; Pierce, D; Velinova, M, 2015
)
0.9
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials5 (100.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other0 (0.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]