Compounds > pyroglutamylalanine amide
Page last updated: 2024-11-07

pyroglutamylalanine amide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

pyroglutamylalanine amide: RN given refers to D-alaninamide; RN for cpd without isomeric designation not in Chemline 1/88 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID127574
SCHEMBL ID18818408
MeSH IDM0153515

Synonyms (8)

Synonym
pyroglutamylalanine amide
(2s)-n-[(2r)-1-amino-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
d-alainamdie, 5-oxo-l-prolyl-
100462-32-6
l-pyroglutamyl-d-alanine amide
SCHEMBL18818408
DTXSID90905515
5-hydroxy-n-(1-hydroxy-1-iminopropan-2-yl)-3,4-dihydro-2h-pyrrole-2-carboximidic acid

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" In massed training, which led to lower levels of learning as compared with spaced training, the dipeptide improved contextual memory, while in spaced training, which led to higher initial learning levels, dosage with dipeptide improved reproduction of the habit."( Modulation of long-term memory by delayed administration of the amide of L-pyroglutamyl-D-alanine, a nootropic agent, in spaced and massed training in rats.
Anokhin, KV; Gudasheva, TA; Ostrovskaya, RU; Vysotskii, AL; Vysotskii, DL, )		0.13
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (3)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.67

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.67 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.62 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.67)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
pyrrolidonecarboxylic acid
Pyrrolidonecarboxylic Acid: A cyclized derivative of L-GLUTAMIC ACID. Elevated blood levels may be associated with problems of GLUTAMINE or GLUTATHIONE metabolism.. 5-oxo-L-proline : An optically active form of 5-oxoproline having L-configuration.		2.67305-oxoproline;
L-proline derivative;
non-proteinogenic L-alpha-amino acid		algal metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Delayed Effects, Prenatal Exposure
[description not available]		01.9810
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.		01.9810