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pradimicin s

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Description

pradimicin S: structure given in first source; isolated from Actinomadura spinosa; the 3'-O-(3''-O-sulfo-beta-D-glucopyranosyl) analog of pradimicin A [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID10079558
CHEMBL ID1673204
MeSH IDM0215976

Synonyms (4)

Synonym
pradimicin s
CHEMBL1673204
pradimicin-s
(2r)-2-[[(5s,6s)-5-[(2s,3r,4s,5s,6r)-4-[(2r,3r,4s,5r,6r)-3,5-dihydroxy-6-(hydroxymethyl)-4-sulfooxyoxan-2-yl]oxy-3-hydroxy-6-methyl-5-(methylamino)oxan-2-yl]oxy-1,6,9,14-tetrahydroxy-11-methoxy-3-methyl-8,13-dioxo-5,6-dihydrobenzo[a]tetracene-2-carbonyl]a
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (136)

Assay IDTitleYearJournalArticle
AID571630Antiviral activity against HIV-1 3B infected in human C8166 cells assessed as inhibition of virus-induced cytopathicity after 3 to 4 days by microscopic analysis2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572325Binding affinity to HIV-1 3B gp120 assessed as association rate constant after 6 mins by SPR analysis in presence of 10 mM CaCl22010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID571628Antiviral activity against HIV-2 ROD infected in human MT4 cells assessed as inhibition of virus-induced cytopathicity after 7 days by trypan blue staining2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575938Chemical stability of the compound in 7mM sodium phosphate buffer after 4 days by HPLC at pH 42010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID571632Cytotoxicity against human CEM cells after 7 days by trypan blue staining2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575917Immunostimulatory activity against human PBMC assessed as TNF-alpha production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID571625Antiviral activity against HIV-1 3B infected in human CEM cells assessed as inhibition of virus-induced cytopathicity after 3 to 4 days by microscopic analysis2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572296Ratio of EC90 to EC50 for R5 tropic HIV-1 clade C isolate ETH2220 infected in human PBMC2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575919Immunostimulatory activity against human PBMC assessed as suppression of IL-2 production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572327Binding affinity to HIV-1 HXB2 gp41 assessed as association rate constant after 6 mins by SPR analysis in presence of 10 mM CaCl22010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572329Binding affinity to HIV-1 3B gp120 after 6 mins by SPR analysis in presence of 10 mM CaCl22010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572342Immunostimulatory activity against human PBMC assessed as IL-8 production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575911Immunostimulatory activity against human PBMC assessed as IP-10 production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575935Immunostimulatory activity against human PBMC assessed as suppression of G-CSF production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575928Immunostimulatory activity against human PBMC assessed as suppression of IL1-beta production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572355Immunostimulatory activity against human PBMC assessed as MIP-1beta production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID571636Antiviral activity against R5 tropic HIV-1 clade C isolate ETH2220 infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575934Immunostimulatory activity against human PBMC assessed as suppression of eotoxin production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575920Immunostimulatory activity against human PBMC assessed as suppression of IL-4 production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575892Immunostimulatory activity against human PBMC assessed as PDGF production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575922Immunostimulatory activity against human PBMC assessed as suppression of IL-13 production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572289Antiviral activity against X4 tropic HIV-1 group O isolate BCF06 infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575940Antiviral activity against HIV-1 3B infected in human HUT78 cells assessed as prevention of syncytium formation between persistently HIV-1 3B-infected HUT-78 cells and uninfected SupT1 cells compound preexposed to high temperature after 3 to 4 days by ELI2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575921Immunostimulatory activity against human PBMC assessed as suppression of IL-9 production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575941Binding affinity to HIV-1 3B gp120 after 6 mins by SPR analysis at pH 42010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572318Antiviral activity against R5 tropic HIV-1 Bal infected in human Raji cells expressing DC-SIGN gene assessed as inhibition of virus capture by Raji cells after 60 mins by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572310Cytotoxicity against human Caco2 cells after 3 to 4 days2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572341Immunostimulatory activity against human PBMC assessed as IL-6 production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572297Ratio of EC90 to EC50 for X4 tropic HIV-1 clade D isolate UG270 infected in human PBMC2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572302Ratio of EC90 to EC50 for X4 tropic HIV-1 3B infected in human PBMC2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID571637Antiviral activity against X4 tropic HIV-1 clade D isolate UG270 infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572317Antiviral activity against X4 tropic HIV-1 3B infected in human Raji cells expressing DC-SIGN gene assessed as inhibition of virus capture by Raji cells after 60 mins by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572293Cytotoxicity against human PBMC after 7 days by trypan blue staining2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572315Antiviral activity against SIV mac251 infected in human HUT78 cells assessed as prevention of syncytium formation between persistently SIV mac251-infected HUT-78 cells and uninfected CEM cells after 3 to 4 days by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572290Antiviral activity against X4 tropic HIV-1 3B infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID571629Antiviral activity against SIV mac251 infected in human MT4 cells assessed as inhibition of virus-induced cytopathicity after 7 days by trypan blue staining2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572309Cytotoxicity against human thymidine kinase-negative OST cells after 3 to 4 days2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572334Antiviral activity against compound pretreated HIV-1 3B isolate 42 harboring gp120 mutant infected in human CEM cells assessed as inhibition of virus-induced cytopathicity after 3 to 4 days by microscopic analysis2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575909Immunostimulatory activity against human PBMC assessed as G-CSF production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID612547Cytotoxicity against human CEM cells after 4 days by by Coulter counter analysis2011Journal of medicinal chemistry, Aug-11, Volume: 54, Issue:15
Targeting HIV entry through interaction with envelope glycoprotein 120 (gp120): synthesis and antiviral evaluation of 1,3,5-triazines with aromatic amino acids.
AID572349Immunostimulatory activity against human PBMC assessed as FGF production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575893Immunostimulatory activity against human PBMC assessed as RANTES production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575896Immunostimulatory activity against human PBMC assessed as IL1-beta production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID571626Antiviral activity against HIV-2 ROD infected in human CEM cells assessed as inhibition of virus-induced cytopathicity after 3 to 4 days by microscopic analysis2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572331Ratio of KD for HIV-1 HXB2 gp41 to KD for HIV-1 3B gp1202010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572332Ratio of Ka for HIV-1 3B gp41 to Ka for HXB2 gp1202010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572294Ratio of EC90 to EC50 for R5 tropic HIV-1 clade A isolate UG273 infected in human PBMC2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575906Immunostimulatory activity against human PBMC assessed as IL-15 production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID571638Antiviral activity against R5 tropic HIV-1 clade A/E isolate ID12 infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575918Immunostimulatory activity against human PBMC assessed as VEGF production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575925Immunostimulatory activity against human PBMC assessed as suppression of G-CSF production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572354Immunostimulatory activity against human PBMC assessed as MIP-1alpha production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575898Immunostimulatory activity against human PBMC assessed as IL-2 production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575895Immunostimulatory activity against human PBMC assessed as VEGF production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572303Ratio of EC90 to EC50 for X4 tropic HIV-1 Bal infected in human PBMC2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572340Immunostimulatory activity against human PBMC assessed as IL-4 production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID571633Cytotoxicity against human MT4 cells after 7 days by trypan blue staining2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575904Immunostimulatory activity against human PBMC assessed as IL-12 production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572307Cytotoxicity against human Molt4 cells after 3 to 4 days2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575937Chemical stability of the compound in PBS solution at 50 degC after 4 days by HPLC2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572335Ratio of EC50 for compound pretreated HIV-1 3B isolate 42 harboring gp120 mutant infected in human CEM cells to EC50 for HIV-1 3B expressing wild type gp1202010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID612571Antiviral activity against HIV1 3B infected in human CEM cells assessed as inhibition of virus-induced cytopathicity after 4 days2011Journal of medicinal chemistry, Aug-11, Volume: 54, Issue:15
Targeting HIV entry through interaction with envelope glycoprotein 120 (gp120): synthesis and antiviral evaluation of 1,3,5-triazines with aromatic amino acids.
AID575936Immunostimulatory activity against human PBMC assessed as suppression of PDGF production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572299Ratio of EC90 to EC50 for R5 tropic HIV-1 clade F isolate BZ163 infected in human PBMC2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575894Immunostimulatory activity against human PBMC assessed as TNF-alpha production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572350Immunostimulatory activity against human PBMC assessed as G-CSF production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572304Ratio of EC90 to EC50 for X4 tropic HIV-2 BV-5061 W infected in human PBMC2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575939Antiviral activity against HIV-1 3B infected in human HUT78 cells assessed as prevention of syncytium formation between persistently HIV-1 3B-infected HUT-78 cells and uninfected SupT1 cells compound preexposed at pH 4 after 3 to 4 days by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572291Antiviral activity against X4 tropic HIV-1 Bal infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572288Antiviral activity against R5 tropic HIV-1 clade G isolate BCF-DIOUM infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575930Immunostimulatory activity against human PBMC assessed as suppression of IL-4 production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572295Ratio of EC90 to EC50 for R5 tropic HIV-1 clade B isolate US2 infected in human PBMC2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575932Immunostimulatory activity against human PBMC assessed as suppression of IL-13 production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575915Immunostimulatory activity against human PBMC assessed as PDGF production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575897Immunostimulatory activity against human PBMC assessed as IL-1ra production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572330Binding affinity to HIV-1 HXB2 gp41 after 6 mins by SPR analysis in presence of 10 mM CaCl22010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572300Ratio of EC90 to EC50 for R5 tropic HIV-1 clade G isolate BCF-DIOUM infected in human PBMC2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572311Cytotoxicity against human U87 cells after 3 to 4 days2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID571635Antiviral activity against R5 tropic HIV-1 clade B isolate US2 infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572287Antiviral activity against R5 tropic HIV-1 clade F isolate BZ163 infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572301Ratio of EC90 to EC50 for X4 tropic HIV-1 group O isolate BCF06 infected in human PBMC2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575914Immunostimulatory activity against human PBMC assessed as MIP-1beta production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575926Immunostimulatory activity against human PBMC assessed as suppression of PDGF production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572321Antiviral activity against SIV mac251 infected in human Raji cells expressing DC-SIGN gene assessed as inhibition of virus capture by Raji cells after 60 mins by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575902Immunostimulatory activity against human PBMC assessed as IL-9 production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575933Immunostimulatory activity against human PBMC assessed as suppression of IL-15 production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575903Immunostimulatory activity against human PBMC assessed as IL-10 production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572351Immunostimulatory activity against human PBMC assessed as GM-CSF production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID571631Antiviral activity against HIV-1 3B cells infected in human PBMC cells assessed as inhibition of virus-induced cytopathicity after 3 to 4 days by microscopic analysis2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572333Ratio of Kd for HIV-1 HXB2 gp120 to KD for HIV-1 3B gp412010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572322Antiviral activity against SIV mac251 infected in human Raji cells expressing DC-SIGN gene assessed as prevention of syncytium formation between persistently HIV-1 3B-infected Raji cells and uninfected human C8166 cells after 60 mins by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572339Immunostimulatory activity against human PBMC assessed as IL-2 production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572312Cytotoxicity against human PBMC cells after 3 to 4 days2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575929Immunostimulatory activity against human PBMC assessed as suppression of RANTES production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572336Antiviral activity against HIV-1 3B harboring wild type gp120 infected in human CEM cells assessed as inhibition of virus-induced cytopathicity after 3 to 4 days by microscopic analysis2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572313Cytotoxicity against human PBMC cells at 500 uM after 7 days2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575916Immunostimulatory activity against human PBMC assessed as RANTES production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572306Cytotoxicity against human C8166 cells after 3 to 4 days2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575927Immunostimulatory activity against human PBMC assessed as suppression of IL-2 production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575901Immunostimulatory activity against human PBMC assessed as IL-8 production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572308Cytotoxicity against human HeLa cells after 3 to 4 days2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572352Immunostimulatory activity against human PBMC assessed as IP-10 production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572338Immunostimulatory activity against human PBMC assessed as IL-1ra production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572345Immunostimulatory activity against human PBMC assessed as IL-12 production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572316Antiviral activity against HIV-1 3B infected in human HUT78 cells assessed as prevention of syncytium formation between persistently HIV-1 3B-infected HUT-78 cells and uninfected SupT1 cells after 3 to 4 days by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575907Immunostimulatory activity against human PBMC assessed as eotoxin production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575923Immunostimulatory activity against human PBMC assessed as suppression of IL-15 production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575899Immunostimulatory activity against human PBMC assessed as IL-4 production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575908Immunostimulatory activity against human PBMC assessed as FGF production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572324Binding affinity to HIV-1 HXB2 gp41 after 6 mins by SPR analysis2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID612570Antiviral activity against HIV2 ROD infected in human CEM cells assessed as inhibition of virus-induced cytopathicity after 4 days2011Journal of medicinal chemistry, Aug-11, Volume: 54, Issue:15
Targeting HIV entry through interaction with envelope glycoprotein 120 (gp120): synthesis and antiviral evaluation of 1,3,5-triazines with aromatic amino acids.
AID572305Cytotoxicity against mouse L1210 cells after 3 to 4 days2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572344Immunostimulatory activity against human PBMC assessed as IL-10 production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575900Immunostimulatory activity against human PBMC assessed as IL-6 production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572347Immunostimulatory activity against human PBMC assessed as IL-15 production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572320Antiviral activity against compound pretreated X4 tropic HIV-1 3B infected in human Raji cells expressing DC-SIGN gene assessed as prevention of syncytium formation between persistently HIV-1 3B-infected Raji cells and uninfected human C8166 cells after 42010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572328Binding affinity to HIV-1 HXB2 gp41 assessed as dissociation rate constant after 6 mins by SPR analysis in presence of 10 mM CaCl22010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572337Immunostimulatory activity against human PBMC assessed as IL1-beta production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572348Immunostimulatory activity against human PBMC assessed as eotoxin production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572343Immunostimulatory activity against human PBMC assessed as IL-9 production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575910Immunostimulatory activity against human PBMC assessed as GM-CSF production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575905Immunostimulatory activity against human PBMC assessed as IL-13 production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID571634Antiviral activity against R5 tropic HIV-1 clade A isolate UG273 infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID571627Antiviral activity against HIV-1 3B infected in human MT4 cells assessed as inhibition of virus-induced cytopathicity after 7 days by trypan blue staining2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575913Immunostimulatory activity against human PBMC assessed as MIP-1alpha production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575924Immunostimulatory activity against human PBMC assessed as suppression of eotoxin production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572353Immunostimulatory activity against human PBMC assessed as MCP-1 production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572292Antiviral activity against X4 tropic HIV-2 BV-5061 W infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572346Immunostimulatory activity against human PBMC assessed as IL-13 production at 21 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575931Immunostimulatory activity against human PBMC assessed as suppression of IL-9 production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572326Binding affinity to HIV-1 3B gp120 assessed as dissociation rate constant after 6 mins by SPR analysis in presence of 10 mM CaCl22010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575942Aqueous solubility of the compound2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID575912Immunostimulatory activity against human PBMC assessed as MCP-1 production at 22 uM after 72 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572319Antiviral activity against X4 tropic HIV-1 3B infected in human Raji cells expressing DC-SIGN gene assessed as prevention of syncytium formation between persistently HIV-1 3B-infected Raji cells and uninfected human C8166 cells after 36 to 42 hrs by micro2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572298Ratio of EC90 to EC50 for R5 tropic HIV-1 clade A/E isolate ID12 infected in human PBMC2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
AID572323Binding affinity to HIV-1 3B gp120 after 6 mins by SPR analysis2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]