Assay ID | Title | Year | Journal | Article |
AID571630 | Antiviral activity against HIV-1 3B infected in human C8166 cells assessed as inhibition of virus-induced cytopathicity after 3 to 4 days by microscopic analysis | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572325 | Binding affinity to HIV-1 3B gp120 assessed as association rate constant after 6 mins by SPR analysis in presence of 10 mM CaCl2 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID571628 | Antiviral activity against HIV-2 ROD infected in human MT4 cells assessed as inhibition of virus-induced cytopathicity after 7 days by trypan blue staining | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575938 | Chemical stability of the compound in 7mM sodium phosphate buffer after 4 days by HPLC at pH 4 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID571632 | Cytotoxicity against human CEM cells after 7 days by trypan blue staining | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575917 | Immunostimulatory activity against human PBMC assessed as TNF-alpha production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID571625 | Antiviral activity against HIV-1 3B infected in human CEM cells assessed as inhibition of virus-induced cytopathicity after 3 to 4 days by microscopic analysis | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572296 | Ratio of EC90 to EC50 for R5 tropic HIV-1 clade C isolate ETH2220 infected in human PBMC | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575919 | Immunostimulatory activity against human PBMC assessed as suppression of IL-2 production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572327 | Binding affinity to HIV-1 HXB2 gp41 assessed as association rate constant after 6 mins by SPR analysis in presence of 10 mM CaCl2 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572329 | Binding affinity to HIV-1 3B gp120 after 6 mins by SPR analysis in presence of 10 mM CaCl2 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572342 | Immunostimulatory activity against human PBMC assessed as IL-8 production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575911 | Immunostimulatory activity against human PBMC assessed as IP-10 production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575935 | Immunostimulatory activity against human PBMC assessed as suppression of G-CSF production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575928 | Immunostimulatory activity against human PBMC assessed as suppression of IL1-beta production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572355 | Immunostimulatory activity against human PBMC assessed as MIP-1beta production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID571636 | Antiviral activity against R5 tropic HIV-1 clade C isolate ETH2220 infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575934 | Immunostimulatory activity against human PBMC assessed as suppression of eotoxin production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575920 | Immunostimulatory activity against human PBMC assessed as suppression of IL-4 production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575892 | Immunostimulatory activity against human PBMC assessed as PDGF production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575922 | Immunostimulatory activity against human PBMC assessed as suppression of IL-13 production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572289 | Antiviral activity against X4 tropic HIV-1 group O isolate BCF06 infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575940 | Antiviral activity against HIV-1 3B infected in human HUT78 cells assessed as prevention of syncytium formation between persistently HIV-1 3B-infected HUT-78 cells and uninfected SupT1 cells compound preexposed to high temperature after 3 to 4 days by ELI | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575921 | Immunostimulatory activity against human PBMC assessed as suppression of IL-9 production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575941 | Binding affinity to HIV-1 3B gp120 after 6 mins by SPR analysis at pH 4 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572318 | Antiviral activity against R5 tropic HIV-1 Bal infected in human Raji cells expressing DC-SIGN gene assessed as inhibition of virus capture by Raji cells after 60 mins by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572310 | Cytotoxicity against human Caco2 cells after 3 to 4 days | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572341 | Immunostimulatory activity against human PBMC assessed as IL-6 production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572297 | Ratio of EC90 to EC50 for X4 tropic HIV-1 clade D isolate UG270 infected in human PBMC | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572302 | Ratio of EC90 to EC50 for X4 tropic HIV-1 3B infected in human PBMC | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID571637 | Antiviral activity against X4 tropic HIV-1 clade D isolate UG270 infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572317 | Antiviral activity against X4 tropic HIV-1 3B infected in human Raji cells expressing DC-SIGN gene assessed as inhibition of virus capture by Raji cells after 60 mins by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572293 | Cytotoxicity against human PBMC after 7 days by trypan blue staining | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572315 | Antiviral activity against SIV mac251 infected in human HUT78 cells assessed as prevention of syncytium formation between persistently SIV mac251-infected HUT-78 cells and uninfected CEM cells after 3 to 4 days by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572290 | Antiviral activity against X4 tropic HIV-1 3B infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID571629 | Antiviral activity against SIV mac251 infected in human MT4 cells assessed as inhibition of virus-induced cytopathicity after 7 days by trypan blue staining | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572309 | Cytotoxicity against human thymidine kinase-negative OST cells after 3 to 4 days | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572334 | Antiviral activity against compound pretreated HIV-1 3B isolate 42 harboring gp120 mutant infected in human CEM cells assessed as inhibition of virus-induced cytopathicity after 3 to 4 days by microscopic analysis | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575909 | Immunostimulatory activity against human PBMC assessed as G-CSF production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID612547 | Cytotoxicity against human CEM cells after 4 days by by Coulter counter analysis | 2011 | Journal of medicinal chemistry, Aug-11, Volume: 54, Issue:15
| Targeting HIV entry through interaction with envelope glycoprotein 120 (gp120): synthesis and antiviral evaluation of 1,3,5-triazines with aromatic amino acids. |
AID572349 | Immunostimulatory activity against human PBMC assessed as FGF production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575893 | Immunostimulatory activity against human PBMC assessed as RANTES production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575896 | Immunostimulatory activity against human PBMC assessed as IL1-beta production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID571626 | Antiviral activity against HIV-2 ROD infected in human CEM cells assessed as inhibition of virus-induced cytopathicity after 3 to 4 days by microscopic analysis | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572331 | Ratio of KD for HIV-1 HXB2 gp41 to KD for HIV-1 3B gp120 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572332 | Ratio of Ka for HIV-1 3B gp41 to Ka for HXB2 gp120 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572294 | Ratio of EC90 to EC50 for R5 tropic HIV-1 clade A isolate UG273 infected in human PBMC | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575906 | Immunostimulatory activity against human PBMC assessed as IL-15 production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID571638 | Antiviral activity against R5 tropic HIV-1 clade A/E isolate ID12 infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575918 | Immunostimulatory activity against human PBMC assessed as VEGF production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575925 | Immunostimulatory activity against human PBMC assessed as suppression of G-CSF production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572354 | Immunostimulatory activity against human PBMC assessed as MIP-1alpha production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575898 | Immunostimulatory activity against human PBMC assessed as IL-2 production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575895 | Immunostimulatory activity against human PBMC assessed as VEGF production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572303 | Ratio of EC90 to EC50 for X4 tropic HIV-1 Bal infected in human PBMC | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572340 | Immunostimulatory activity against human PBMC assessed as IL-4 production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID571633 | Cytotoxicity against human MT4 cells after 7 days by trypan blue staining | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575904 | Immunostimulatory activity against human PBMC assessed as IL-12 production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572307 | Cytotoxicity against human Molt4 cells after 3 to 4 days | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575937 | Chemical stability of the compound in PBS solution at 50 degC after 4 days by HPLC | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572335 | Ratio of EC50 for compound pretreated HIV-1 3B isolate 42 harboring gp120 mutant infected in human CEM cells to EC50 for HIV-1 3B expressing wild type gp120 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID612571 | Antiviral activity against HIV1 3B infected in human CEM cells assessed as inhibition of virus-induced cytopathicity after 4 days | 2011 | Journal of medicinal chemistry, Aug-11, Volume: 54, Issue:15
| Targeting HIV entry through interaction with envelope glycoprotein 120 (gp120): synthesis and antiviral evaluation of 1,3,5-triazines with aromatic amino acids. |
AID575936 | Immunostimulatory activity against human PBMC assessed as suppression of PDGF production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572299 | Ratio of EC90 to EC50 for R5 tropic HIV-1 clade F isolate BZ163 infected in human PBMC | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575894 | Immunostimulatory activity against human PBMC assessed as TNF-alpha production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572350 | Immunostimulatory activity against human PBMC assessed as G-CSF production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572304 | Ratio of EC90 to EC50 for X4 tropic HIV-2 BV-5061 W infected in human PBMC | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575939 | Antiviral activity against HIV-1 3B infected in human HUT78 cells assessed as prevention of syncytium formation between persistently HIV-1 3B-infected HUT-78 cells and uninfected SupT1 cells compound preexposed at pH 4 after 3 to 4 days by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572291 | Antiviral activity against X4 tropic HIV-1 Bal infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572288 | Antiviral activity against R5 tropic HIV-1 clade G isolate BCF-DIOUM infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575930 | Immunostimulatory activity against human PBMC assessed as suppression of IL-4 production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572295 | Ratio of EC90 to EC50 for R5 tropic HIV-1 clade B isolate US2 infected in human PBMC | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575932 | Immunostimulatory activity against human PBMC assessed as suppression of IL-13 production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575915 | Immunostimulatory activity against human PBMC assessed as PDGF production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575897 | Immunostimulatory activity against human PBMC assessed as IL-1ra production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572330 | Binding affinity to HIV-1 HXB2 gp41 after 6 mins by SPR analysis in presence of 10 mM CaCl2 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572300 | Ratio of EC90 to EC50 for R5 tropic HIV-1 clade G isolate BCF-DIOUM infected in human PBMC | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572311 | Cytotoxicity against human U87 cells after 3 to 4 days | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID571635 | Antiviral activity against R5 tropic HIV-1 clade B isolate US2 infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572287 | Antiviral activity against R5 tropic HIV-1 clade F isolate BZ163 infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572301 | Ratio of EC90 to EC50 for X4 tropic HIV-1 group O isolate BCF06 infected in human PBMC | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575914 | Immunostimulatory activity against human PBMC assessed as MIP-1beta production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575926 | Immunostimulatory activity against human PBMC assessed as suppression of PDGF production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572321 | Antiviral activity against SIV mac251 infected in human Raji cells expressing DC-SIGN gene assessed as inhibition of virus capture by Raji cells after 60 mins by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575902 | Immunostimulatory activity against human PBMC assessed as IL-9 production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575933 | Immunostimulatory activity against human PBMC assessed as suppression of IL-15 production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575903 | Immunostimulatory activity against human PBMC assessed as IL-10 production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572351 | Immunostimulatory activity against human PBMC assessed as GM-CSF production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID571631 | Antiviral activity against HIV-1 3B cells infected in human PBMC cells assessed as inhibition of virus-induced cytopathicity after 3 to 4 days by microscopic analysis | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572333 | Ratio of Kd for HIV-1 HXB2 gp120 to KD for HIV-1 3B gp41 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572322 | Antiviral activity against SIV mac251 infected in human Raji cells expressing DC-SIGN gene assessed as prevention of syncytium formation between persistently HIV-1 3B-infected Raji cells and uninfected human C8166 cells after 60 mins by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572339 | Immunostimulatory activity against human PBMC assessed as IL-2 production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572312 | Cytotoxicity against human PBMC cells after 3 to 4 days | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575929 | Immunostimulatory activity against human PBMC assessed as suppression of RANTES production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572336 | Antiviral activity against HIV-1 3B harboring wild type gp120 infected in human CEM cells assessed as inhibition of virus-induced cytopathicity after 3 to 4 days by microscopic analysis | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572313 | Cytotoxicity against human PBMC cells at 500 uM after 7 days | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575916 | Immunostimulatory activity against human PBMC assessed as RANTES production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572306 | Cytotoxicity against human C8166 cells after 3 to 4 days | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575927 | Immunostimulatory activity against human PBMC assessed as suppression of IL-2 production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575901 | Immunostimulatory activity against human PBMC assessed as IL-8 production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572308 | Cytotoxicity against human HeLa cells after 3 to 4 days | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572352 | Immunostimulatory activity against human PBMC assessed as IP-10 production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572338 | Immunostimulatory activity against human PBMC assessed as IL-1ra production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572345 | Immunostimulatory activity against human PBMC assessed as IL-12 production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572316 | Antiviral activity against HIV-1 3B infected in human HUT78 cells assessed as prevention of syncytium formation between persistently HIV-1 3B-infected HUT-78 cells and uninfected SupT1 cells after 3 to 4 days by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575907 | Immunostimulatory activity against human PBMC assessed as eotoxin production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575923 | Immunostimulatory activity against human PBMC assessed as suppression of IL-15 production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575899 | Immunostimulatory activity against human PBMC assessed as IL-4 production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575908 | Immunostimulatory activity against human PBMC assessed as FGF production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572324 | Binding affinity to HIV-1 HXB2 gp41 after 6 mins by SPR analysis | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID612570 | Antiviral activity against HIV2 ROD infected in human CEM cells assessed as inhibition of virus-induced cytopathicity after 4 days | 2011 | Journal of medicinal chemistry, Aug-11, Volume: 54, Issue:15
| Targeting HIV entry through interaction with envelope glycoprotein 120 (gp120): synthesis and antiviral evaluation of 1,3,5-triazines with aromatic amino acids. |
AID572305 | Cytotoxicity against mouse L1210 cells after 3 to 4 days | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572344 | Immunostimulatory activity against human PBMC assessed as IL-10 production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575900 | Immunostimulatory activity against human PBMC assessed as IL-6 production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572347 | Immunostimulatory activity against human PBMC assessed as IL-15 production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572320 | Antiviral activity against compound pretreated X4 tropic HIV-1 3B infected in human Raji cells expressing DC-SIGN gene assessed as prevention of syncytium formation between persistently HIV-1 3B-infected Raji cells and uninfected human C8166 cells after 4 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572328 | Binding affinity to HIV-1 HXB2 gp41 assessed as dissociation rate constant after 6 mins by SPR analysis in presence of 10 mM CaCl2 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572337 | Immunostimulatory activity against human PBMC assessed as IL1-beta production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572348 | Immunostimulatory activity against human PBMC assessed as eotoxin production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572343 | Immunostimulatory activity against human PBMC assessed as IL-9 production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575910 | Immunostimulatory activity against human PBMC assessed as GM-CSF production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575905 | Immunostimulatory activity against human PBMC assessed as IL-13 production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID571634 | Antiviral activity against R5 tropic HIV-1 clade A isolate UG273 infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID571627 | Antiviral activity against HIV-1 3B infected in human MT4 cells assessed as inhibition of virus-induced cytopathicity after 7 days by trypan blue staining | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575913 | Immunostimulatory activity against human PBMC assessed as MIP-1alpha production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575924 | Immunostimulatory activity against human PBMC assessed as suppression of eotoxin production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572353 | Immunostimulatory activity against human PBMC assessed as MCP-1 production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572292 | Antiviral activity against X4 tropic HIV-2 BV-5061 W infected in human PBMC assessed as inhibition of viral replication after 3 days by ELISA | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572346 | Immunostimulatory activity against human PBMC assessed as IL-13 production at 21 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575931 | Immunostimulatory activity against human PBMC assessed as suppression of IL-9 production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572326 | Binding affinity to HIV-1 3B gp120 assessed as dissociation rate constant after 6 mins by SPR analysis in presence of 10 mM CaCl2 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575942 | Aqueous solubility of the compound | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID575912 | Immunostimulatory activity against human PBMC assessed as MCP-1 production at 22 uM after 72 hrs | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572319 | Antiviral activity against X4 tropic HIV-1 3B infected in human Raji cells expressing DC-SIGN gene assessed as prevention of syncytium formation between persistently HIV-1 3B-infected Raji cells and uninfected human C8166 cells after 36 to 42 hrs by micro | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572298 | Ratio of EC90 to EC50 for R5 tropic HIV-1 clade A/E isolate ID12 infected in human PBMC | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
AID572323 | Binding affinity to HIV-1 3B gp120 after 6 mins by SPR analysis | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
| Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |