haloxyfop-P-methyl
Description
haloxyfop-P-methyl : A methyl 2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoate that has R configuration. It is a proherbicide (by hydrolysis of the methyl ester) for the herbicide haloxyfop-P, the most active enantiomer of the racemic herbicide haloxyfop. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 13363033 |
CHEMBL ID | 2286458 |
CHEBI ID | 136729 |
SCHEMBL ID | 54814 |
Synonyms (40)
Synonym |
---|
edge |
methyl (2r)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoate |
(r)-haloxyfop methyl ester |
methyl (r)-2-{4-[3-chloro-5-(trifluoromethyl)-2-pyridyloxy]phenoxy}propionate |
haloxyfop-p-methyl |
gallant super |
72619-32-0 |
CHEBI:136729 |
methyl (2r)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propionate |
methyl (2r)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoate |
eloge |
de 535 |
zellek super |
unii-7vd796hhts |
methyl (r)-2-(4-(3-chloro-5-trifluoromethyl-2-pyridyloxy)phenoxy)propionate |
haloxyfop-p-methyl [iso] |
7vd796hhts , |
ec 406-250-0 |
(r)-methyl 2-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenoxy)propanoate |
c16h13clf3no4 |
AKOS015895898 |
propanoic acid, 2-(4-((3-chloro-5-(trifluoromethyl)-2-pyridinyl)oxy)phenoxy)-, methyl ester, (2r)- |
de-535 |
186673-58-5 |
SCHEMBL54814 |
CHEMBL2286458 |
DTXSID8058249 |
haloxyfop-p-methyl, pestanal(r), analytical standard |
propanoic acid, 2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]-, methyl ester, (2r)- |
haloxyfop-r-methyl 10 microg/ml in acetonitrile |
methyl (r)-2-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenoxy)propanoate |
(r)-methyl 2-(4-((3-chloro-5-(trifluoromethyl)-pyridin-2-yl)oxy)phenoxy)propanoate |
(r)-methyl 2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yloxy)phenoxy)propanoate |
MFSWTRQUCLNFOM-SECBINFHSA-N , |
haloxyfop-(r)-methyl |
AS-13063 |
methyl (2r)-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate |
Q27268911 |
CS-0128835 |
HY-136374 |
Research Excerpts
Toxicity
Excerpt | Reference | Relevance |
---|---|---|
"Haloxyfop-P-methyl is used extensively in agricultural production, and its metabolites in soil have potentially toxic effects on aquatic ecosystems." | ( Haloxyfop-P-methyl induces immunotoxicity and glucose metabolism disorders and affects the Nrf2/ARE pathway mediated antioxidant system in Chiromantes dehaani. Du, X; Li, Y; Liu, Z; Tian, J; Xu, W; Yang, Y; Ye, Y; Zhao, Y, 2023) | 3.8 |
Roles (3)
Role | Description |
---|---|
proherbicide | A compound that, on administration, must undergo chemical conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the pharmacologically active herbicide for which it is a proherbicide. |
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor | An EC 6.4.1.* (C-C bond-forming ligase) inhibitor that interferes with the action of acetyl-CoA carboxylase (EC 6.4.1.2). |
agrochemical | An agrochemical is a substance that is used in agriculture or horticulture. |
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Drug Classes (1)
Class | Description |
---|---|
methyl 2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoate | The methyl ester of 2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid. |
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Bioassays (12)
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID1111576 | Herbicidal activity against Sorghum bicolor assessed as inhibitory rate of fresh weight gain at 7.5 g/hm'2 relative to control | 2010 | Carbohydrate research, Sep-03, Volume: 345, Issue:13 | Novel 2'-hydroxylfurylchalcones: synthesis and biological activity. |
AID1111579 | Herbicidal activity against Triticum aestivum (wheat) assessed as inhibitory rate of seedling height at 7.5 g/hm'2 relative to control | 2010 | Carbohydrate research, Sep-03, Volume: 345, Issue:13 | Novel 2'-hydroxylfurylchalcones: synthesis and biological activity. |
AID1111578 | Herbicidal activity against Triticum aestivum (wheat) assessed as inhibitory rate of fresh weight gain at 7.5 g/hm'2 relative to control | 2010 | Carbohydrate research, Sep-03, Volume: 345, Issue:13 | Novel 2'-hydroxylfurylchalcones: synthesis and biological activity. |
AID1111584 | Herbicidal activity against Cucumis sativus (cucumber) assessed as inhibitory rate of fresh weight gain at 7.5 g/hm'2 relative to control | 2010 | Carbohydrate research, Sep-03, Volume: 345, Issue:13 | Novel 2'-hydroxylfurylchalcones: synthesis and biological activity. |
AID1111574 | Herbicidal activity against Dinebra chinensis assessed as inhibitory rate of seedling height at 7.5 g/hm'2 relative to control | 2010 | Carbohydrate research, Sep-03, Volume: 345, Issue:13 | Novel 2'-hydroxylfurylchalcones: synthesis and biological activity. |
AID1111585 | Herbicidal activity against Cucumis sativus (cucumber) assessed as inhibitory rate of seedling height at 7.5 g/hm'2 relative to control | 2010 | Carbohydrate research, Sep-03, Volume: 345, Issue:13 | Novel 2'-hydroxylfurylchalcones: synthesis and biological activity. |
AID1111583 | Herbicidal activity against Brassica rapa subsp. oleifera assessed as inhibitory rate of seedling height at 7.5 g/hm'2 relative to control | 2010 | Carbohydrate research, Sep-03, Volume: 345, Issue:13 | Novel 2'-hydroxylfurylchalcones: synthesis and biological activity. |
AID1111577 | Herbicidal activity against Sorghum bicolor assessed as inhibitory rate of seedling height at 7.5 g/hm'2 relative to control | 2010 | Carbohydrate research, Sep-03, Volume: 345, Issue:13 | Novel 2'-hydroxylfurylchalcones: synthesis and biological activity. |
AID1111582 | Herbicidal activity against Brassica rapa subsp. oleifera assessed as inhibitory rate of fresh weight gain at 7.5 g/hm'2 relative to control | 2010 | Carbohydrate research, Sep-03, Volume: 345, Issue:13 | Novel 2'-hydroxylfurylchalcones: synthesis and biological activity. |
AID1111581 | Herbicidal activity against Amaranthus tricolor assessed as inhibitory rate of seedling height at 7.5 g/hm'2 relative to control | 2010 | Carbohydrate research, Sep-03, Volume: 345, Issue:13 | Novel 2'-hydroxylfurylchalcones: synthesis and biological activity. |
AID1111580 | Herbicidal activity against Amaranthus tricolor assessed as inhibitory rate of fresh weight gain at 7.5 g/hm'2 relative to control | 2010 | Carbohydrate research, Sep-03, Volume: 345, Issue:13 | Novel 2'-hydroxylfurylchalcones: synthesis and biological activity. |
AID1111575 | Herbicidal activity against Dinebra chinensis assessed as inhibitory rate of fresh weight gain at 7.5 g/hm'2 relative to control | 2010 | Carbohydrate research, Sep-03, Volume: 345, Issue:13 | Novel 2'-hydroxylfurylchalcones: synthesis and biological activity. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (5)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 4 (80.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 39.00
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| This Compound (39.00) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |