daphenylline: an alkaloid with an unusual skeleton from Daphniphyllum longeracemosum; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Daphniphyllum | genus | Broad-leaved evergreen shrub or small tree comprising several species. It is the only genus of the family DAPHNIPHYLLACEAE, class MAGNOLIOPSIDA.[MeSH] | Daphniphyllaceae | Vascular plants of the order SAXIFRAGALES, class MAGNOLIOPSIDA, of which the sole genus is DAPHNIPHYLLUM.[MeSH] |
| ID Source | ID |
|---|---|
| PubMed CID | 44140286 |
| MeSH ID | M0536890 |
| Synonym |
|---|
| daphenylline |
| 9rv40l3mlu , |
| (-)-daphenylline |
| daphenylline [mi] |
| unii-9rv40l3mlu |
| 6h-11,2,12-(1)propen(1)yl(3)ylidyneazuleno(5,6-a)indolizine, 1,2,3,4,6a,7,8,8a,9,10,12a,12b-dodecahydro-3,12a-dimethyl-, (2r,3s,5s,6as,8as,12as,12br)- |
| (2r,3s,5s,6as,8as,12as,12br)-1,2,3,4,6a,7,8,8a,9,10,12a,12b-dodecahydro-3,12a-dimethyl-6h-11,2,12-(1)propen(1)yl(3)ylidyneazuleno(5,6-a)indolizine |
| 1152598-44-1 |
Daphenylline is a structurally unique member among the predominately aliphatic Daphniphyllum alkaloids. It contains a tetrasubstituted arene moiety mounted on a sterically compact hexacyclic scaffold.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Daphenylline is a structurally unique member among the predominately aliphatic Daphniphyllum alkaloids, and contains a tetrasubstituted arene moiety mounted on a sterically compact hexacyclic scaffold." | ( Total synthesis of the Daphniphyllum alkaloid daphenylline. Deng, J; Li, A; Li, Y; Lu, Z, 2013) | 1.37 |
| "Daphenylline is a recently isolated Daphniphyllum alkaloid with an unprecedented novel hexacyclic scaffold. " | ( Diels-Alder/oxidative aromatization approach towards the all-carbon DEF tricyclic skeleton of daphenylline. Li, H; Qiu, Y; She, X; Xie, X; Yuan, Z; Zhao, C, 2014) | 2.06 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (27.75) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||