Page last updated: 2024-12-08
cylindrin
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
cylindrin: erythrocyte membrane protein which contains two predominant polypeptide chains of 22,500 & 28,000 MW with smaller quantity of a 25,500 MW band; do not confuse with cylindrin in Chemline, a synonym for isoarborinol methyl ether [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 189045 |
| CHEBI ID | 81166 |
| SCHEMBL ID | 3679265 |
| MeSH ID | M0097776 |
Synonyms (14)
| Synonym |
|---|
| 17904-55-1 |
| cylindrin |
| C17534 |
| (3s,3as,5as,5bs,7ar,9s,11as,13ar,13bs)-9-methoxy-3a,5a,8,8,11a,13a-hexamethyl-3-propan-2-yl-1,2,3,4,5,5b,6,7,7a,9,10,11,13,13b-tetradecahydrocyclopenta[a]chrysene |
| d:c-friedo-b':a'-neogammacer-9(11)-ene, 3-methoxy-, (3beta,8beta,13beta,14alpha,17beta,18alpha,21beta)- |
| SCHEMBL3679265 |
| CHEBI:81166 |
| Q-100936 |
| Q27155121 |
| 9-methoxy-3a,5a,8,8,11a,13a-hexamethyl-3-(propan-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,9,10,11,11a,13,13a,13b-octadecahydro-1h-cyclopenta[a]chrysene |
| DTXSID30939172 |
| HY-121227 |
| CS-0081264 |
| AKOS040745691 |
Research Excerpts
Overview
Cylindrin is a six-stranded antiparallel beta barrel obtained from amyloidogenic strands of crystallin.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Cylindrin is a six-stranded antiparallel beta barrel obtained from amyloidogenic strands of crystallin. " | ( Comparative modeling of hypothetical amyloid pores based on cylindrin. Kotulska, M; Zulpo, M, 2015) | 2.1 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Drug Classes (1)
| Class | Description |
|---|---|
| triterpenoid | Any terpenoid derived from a triterpene. The term includes compounds in which the C30 skeleton of the parent triterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Research
Studies (12)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 22.42
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (22.42) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (8.33%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 11 (91.67%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||