Page last updated: 2024-11-12
cycloalliin
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
cycloalliin: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 12305351 |
| CHEBI ID | 173815 |
| MeSH ID | M0064117 |
Synonyms (13)
| Synonym |
|---|
| CHEBI:173815 |
| 5-methyl-1-oxo-1,4-thiazinane-3-carboxylic acid |
| cycloalliin |
| 15042-85-0 |
| AKOS014315875 |
| 5-methylthiomorpholine-3-carboxylic acid 1-oxide |
| 5-methyl-1-oxo-1lambda~4~,4-thiazinane-3-carboxylic acid |
| DTXSID60486725 |
| 5-methyl-1-oxo-1$l^{4},4-thiomorpholine-3-carboxylic acid |
| 5-methyl-3-thiomorpholinecarboxylic acid 1-oxide, 9ci |
| 3-thiomorpholinecarboxylicacid,5-methyl-,1-oxide |
| EN300-6941981 |
| 5-methyl-1-oxo-1lambda4-thiomorpholine-3-carboxylic acid |
Research Excerpts
Overview
Cycloalliin is a natural constituent of onion, sulphur-containing but odourless.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Cycloalliin is a natural constituent of onion, sulphur-containing but odourless. " | ( Controlled trial of the effect of cycloalliin on the fibrinolytic activity of venous blood. Agarwal, RK; Das, B; Dewar, HA; Newell, DJ, 1977) | 1.98 |
Bioavailability
| Excerpt | Reference | Relevance |
|---|---|---|
| " These data indicated that the low bioavailability (3." | ( Pharmacokinetics of cycloalliin, an organosulfur compound found in garlic and onion, in rats. Hayama, M; Ichikawa, M; Ide, N; Kodera, Y; Mizuno, I; Ono, K; Ushijima, M; Yoshida, J, 2006) | 0.66 |
Dosage Studied
| Excerpt | Relevance | Reference |
|---|---|---|
| " It was well tolerated and harmless in the single oral dosage used." | ( Controlled trial of the effect of cycloalliin on the fibrinolytic activity of venous blood. Agarwal, RK; Das, B; Dewar, HA; Newell, DJ, 1977) | 0.54 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Drug Classes (1)
| Class | Description |
|---|---|
| alpha-amino acid | An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Research
Studies (6)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 23.62
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (23.62) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 1 (16.67%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (83.33%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||