Page last updated: 2024-11-12

cycloalliin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

cycloalliin: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID12305351
CHEBI ID173815
MeSH IDM0064117

Synonyms (13)

Synonym
CHEBI:173815
5-methyl-1-oxo-1,4-thiazinane-3-carboxylic acid
cycloalliin
15042-85-0
AKOS014315875
5-methylthiomorpholine-3-carboxylic acid 1-oxide
5-methyl-1-oxo-1lambda~4~,4-thiazinane-3-carboxylic acid
DTXSID60486725
5-methyl-1-oxo-1$l^{4},4-thiomorpholine-3-carboxylic acid
5-methyl-3-thiomorpholinecarboxylic acid 1-oxide, 9ci
3-thiomorpholinecarboxylicacid,5-methyl-,1-oxide
EN300-6941981
5-methyl-1-oxo-1lambda4-thiomorpholine-3-carboxylic acid

Research Excerpts

Overview

Cycloalliin is a natural constituent of onion, sulphur-containing but odourless.

ExcerptReferenceRelevance
"Cycloalliin is a natural constituent of onion, sulphur-containing but odourless. "( Controlled trial of the effect of cycloalliin on the fibrinolytic activity of venous blood.
Agarwal, RK; Das, B; Dewar, HA; Newell, DJ, 1977
)
1.98

Bioavailability

ExcerptReferenceRelevance
" These data indicated that the low bioavailability (3."( Pharmacokinetics of cycloalliin, an organosulfur compound found in garlic and onion, in rats.
Hayama, M; Ichikawa, M; Ide, N; Kodera, Y; Mizuno, I; Ono, K; Ushijima, M; Yoshida, J, 2006
)
0.66

Dosage Studied

ExcerptRelevanceReference
" It was well tolerated and harmless in the single oral dosage used."( Controlled trial of the effect of cycloalliin on the fibrinolytic activity of venous blood.
Agarwal, RK; Das, B; Dewar, HA; Newell, DJ, 1977
)
0.54
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
alpha-amino acidAn amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 23.62

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index23.62 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.06 (4.65)
Search Engine Demand Index23.28 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (23.62)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (16.67%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (83.33%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]