Assay ID | Title | Year | Journal | Article |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
AID711864 | Inhibition of APEH binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711876 | Inhibition of PME1 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID712205 | Inhibition of PME1 binding to FP-rhodamine in human HEK293T cells after 45 mins by fluorescence polarization activity-based protein profiling assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711850 | Inhibition of ABHD6 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711854 | Inhibition of DPP9 binding to FP-biotin in[12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID712202 | Binding affinity to PME1 assessed as compound-enzyme serine nuclephile adduct formation by MS analysis | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711851 | Inhibition of PREPL binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711859 | Inhibition of SCPEP1 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711844 | Inhibition of PME1 overexpressed in HEK293T cells assessed as increase in methylated PP2A level at 20 uM after 1 hr by Western blot analysis | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711870 | Inhibition of LYPLA1 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711858 | Inhibition of PLA2G4A binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID712204 | Selectivity ratio of IC50 for acyl peptide hydrolase in human HEK293T cells to IC50 for PME1 in human HEK293T cells | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711857 | Inhibition of PAFAH1B3 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711843 | Inhibition of PME1 expressed in untransfected HEK293T cells assessed as reduction in demethylated PP2A level at 20 uM after 1 hr by Western blot analysis | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711866 | Inhibition of PRCP binding to FP-biotin in[12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711861 | Inhibition of DPP8 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711856 | Inhibition of BAT5 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711853 | Inhibition of CTSA binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711867 | Inhibition of PREP binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711874 | Inhibition of PPT2 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711865 | Inhibition of LYPLAL1 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711849 | Inhibition of PNPLA8 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711872 | Inhibition of ACOT2 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711878 | Inhibition of PME1 binding to FP-rhodamine in mouse brain soluble proteome after 45 mins by fluorescence polarization activity-based protein profiling assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711875 | Inhibition of DAGLB binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711855 | Inhibition of ESD binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711846 | Effect on sulfonate ester-Rh labeled soluble proteome in HEK293T cells at 100 uM incubated for 1 hr before proteome labeling measured after 1 hr relative to control | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711852 | Inhibition of PNPLA6 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711871 | Inhibition of LYPLA3 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711863 | Inhibition of PAFAH1B2 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711877 | Inhibition of PME1 binding to FP-rhodamine in HEK293T cells after 1 hr by fluorescence polarization activity-based protein profiling assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711873 | Inhibition of ACOT1 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711860 | Inhibition of AADACL1 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711869 | Inhibition of FASN binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID712203 | Irreversible inhibition of PME1 binding to FP-rhodamine in human HEK293T cells at 50 uM after 30 mins by gel filtration chromatographic analysis | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711868 | Inhibition of ABHD11 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711848 | Inhibition of C13orf27 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711845 | Inhibition of PME1 overexpressed in HEK293T cells assessed as reduction in demethylated PP2A level at 20 uM after 1 hr by Western blot analysis relative to control | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711847 | Effect on chloroacetamide-Rh labeled soluble proteome in HEK293T cells at 100 uM incubated for 1 hr before protein labeling measured after 1 hr relative to control | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
AID711862 | Inhibition of FAM108B1 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |