Compounds > amphimedine
Page last updated: 2024-11-07

amphimedine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

Amphimedine is a marine natural product isolated from the sponge _Amphimedon quinquesetata_ in 1990. It exhibits a wide range of biological activities, including anti-cancer, anti-inflammatory, and anti-microbial properties. Amphimedine is a complex molecule with a unique structure, which has made its synthesis a challenging task. However, several research groups have reported successful syntheses of amphimedine and its analogs. Its potent biological activities and structural complexity have made it a target of interest for medicinal chemistry research. Researchers are studying amphimedine to understand its mechanisms of action and to develop new drugs based on its structure.'

amphimedine: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID100819
SCHEMBL ID7220001
MeSH IDM0452102

Synonyms (14)

Synonym
8h-benzo(b)pyrido(4,3,2-de)(1,8)phenanthroline-8,11(10h)-dione, 10-methyl-
amphimedine
86047-14-5
nsc377099
nsc-377099
8vi87r49cg ,
nsc 377099
unii-8vi87r49cg
amphimallon majaliseuropean chafer is also indexed at this headingamphimedine
DTXSID90235364
SCHEMBL7220001
10-methyl-8h-benzo(b)pyrido(4,3,2-de)(1,8)phenanthroline-8,11(10h)-dione
5-methyl-5,10,20-triazapentacyclo[11.7.1.02,7.09,21.014,19]henicosa-1(20),2,6,9,11,13(21),14,16,18-nonaene-4,8-dione
AKOS040750495

Research Excerpts

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (20.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
acridines
Acridines: Compounds that include the structure of acridine.. acridine : A polycyclic heteroarene that is anthracene in which one of the central CH groups is replaced by a nitrogen atom.		4.2450acridines;
mancude organic heterotricyclic parent;
polycyclic heteroarene		genotoxin
2-iodobenzenamine
2-iodobenzenamine: structure in first source		2.110
1,7-phenanthroline
[no description available]		4.2450phenanthroline
ethylnicotinate
[no description available]		2.110aromatic carboxylic acid;
pyridines
ascididemin
ascididemin: can be viewed as a fused phenanthroline with quinoline; from the Mediterranean ascidian Cystodytes dellechiajei; structure in first source		3.1210
lithium
Lithium: An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.		2.110alkali metal atom
pyridoacridine
pyridoacridine: structure in first source		4.0640
ConditionIndicatedRelationship StrengthStudiesTrials