Compounds > 2-methoxymethyl-p-phenylenediamine
Page last updated: 2024-12-11

2-methoxymethyl-p-phenylenediamine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2-methoxymethyl-p-phenylenediamine: a primary intermediate for oxidative hair dyes [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9793859
SCHEMBL ID108757
MeSH IDM0592631

Synonyms (22)

Synonym
2-(methoxymethyl)benzene-1,4-diamine
AVKBLCWBDLLVRL-UHFFFAOYSA-N
2-methoxymethyl-1,4-benzenediamine
unii-5982w4u40m
5982w4u40m ,
2-methoxymethyl-p-phenylenediamine [inci]
1,4-diamino-2-(methoxymethyl)benzene
2-methoxymethyl-p-phenylenediamine
ec 679-526-3
337906-36-2
1,4-benzenediamine, 2-(methoxymethyl)-
SCHEMBL108757
mfcd20690892
DTXSID50187451
AKOS027250641
DS-18961
C74735
Q27261675
A924582
SB76075
CS-0161584
SY344744

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
"0% (highest dose), indicating decreased reactivity as compared with published PPD dose-response data."( Cross-elicitation responses to 2-methoxymethyl-p-phenylenediamine in p-phenylenediamine-allergic individuals: Results from open use testing and diagnostic patch testing.
Blömeke, B; Burgerhof, JGM; Dittmar, D; Goebel, C; Schuttelaar, ML, 2018)		0.77
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (100.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 32.59

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index32.59 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index36.32 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (32.59)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational1 (14.29%)0.25%
Other6 (85.71%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
4-phenylenediamine
4-phenylenediamine: agent hair dye responsible for contact dermatitis; RN given refers to parent cpd. 1,4-phenylenediamine : A phenylenediamine in which the amino functions are at positions 1 and 4 of the benzene nucleus.		3.2550phenylenediamineallergen;
dye;
hapten;
reagent
ConditionIndicatedRelationship StrengthStudiesTrials
Allergic Contact Dermatitis
[description not available]		03.460
Dermatitis, Allergic Contact
A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure.		03.460
Dermatitis Medicamentosa
[description not available]		02.1310