Compounds > 1,4-phenanthrenequinone
Page last updated: 2024-11-07

1,4-phenanthrenequinone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

1,4-Phenanthrenequinone is a yellow crystalline solid with a melting point of 206–207 °C. It is synthesized by oxidation of phenanthrene, often using chromic acid. It is a versatile compound with a rich chemistry, serving as a building block for a variety of other compounds. 1,4-Phenanthrenequinone has been studied for its potential biological activity, including its ability to act as a DNA intercalator and to inhibit the growth of certain cancer cells. It has also been investigated for its photophysical properties, including its ability to fluoresce and to undergo photoreduction. Researchers are interested in studying 1,4-phenanthrenequinone because of its potential applications in organic electronics, pharmaceuticals, and materials science.'

1,4-phenanthrenequinone: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID98574
SCHEMBL ID64776
MeSH IDM0276246

Synonyms (21)

Synonym
c14h8o2
phenanthrene-1,4-quinone
5,8-phenanthraquinone
1,4-phenanthrenequinone
nsc 148970
1,4-phenanthroquinone
brn 1871015
1,4-phenanthraquinone
1,4-phenanthrenedione
nsc-148970
nsc148970
569-15-3
phenanthrene-1,4-dione
2-07-00-00724 (beilstein handbook reference)
unii-iu5xp36k84
iu5xp36k84 ,
SCHEMBL64776
DTXSID40205431
FT-0749369
dimeflinehcl
1,4-dihydrophenanthrene-1,4-dione
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.54

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.54 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.73 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.54)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
hypericin
[no description available]		210
9,10-phenanthrenequinone
9,10-phenanthrenequinone: structure		1.9910phenanthrenes
perylene
Perylene: A 20-carbon dibenz(de,kl)anthracene that can be viewed as a naphthalene fused to a phenalene or as dinaphthalene. It is used as fluorescent lipid probe in the cytochemistry of membranes and is a polycyclic hydrocarbon pollutant in soil and water. Derivatives may be carcinogenic.. perylene : An ortho- and peri-fused polycyclic arene comprising of five benzene rings that is anthracene in which the d,e and k,l sides are fused to benzene rings.		210ortho- and peri-fused polycyclic arene;
perylenes
tanshinone
tanshinone: from root of Salvia miltiorrhiza Bunge; RN given refers to tanshinone I; cardioprotective agent and neuroprotective agent		2.1510abietane diterpenoidanticoronaviral agent
stilbenes
Stilbenes: Organic compounds that contain 1,2-diphenylethylene as a functional group.. trans-stilbene : The trans-isomer of stilbene.		2.0610stilbene
denbinobin
denbinobin: antineoplastic from Dendrobium moniliforme (Orchidaceae); structure in first source		7.0410
phenanthrenes
Phenanthrenes: POLYCYCLIC AROMATIC HYDROCARBONS composed of three fused BENZENE rings.. phenanthrenes : Any benzenoid aromatic compound that consists of a phenanthrene skeleton and its substituted derivatives thereof.		3.5480
ConditionIndicatedRelationship StrengthStudiesTrials
Carcinoma, Epidermoid
[description not available]		02.0710
Leucocythaemia
[description not available]		02.0710
Carcinoma, Squamous Cell
A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)		02.0710
Leukemia
A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)		02.0710
Allergic Contact Dermatitis
[description not available]		02.0110
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.		02.0110
Dermatitis, Allergic Contact
A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure.		02.0110
Abnormalities, Autosome
[description not available]		01.9910