glucose-6-phosphate transmembrane transporter activity

Definition

Target type: molecularfunction

Enables the transfer of glucose-6-phosphate from one side of a membrane to the other. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6. [GOC:ai, GOC:mtg_transport, ISBN:0815340729]

Glucose-6-phosphate transmembrane transporter activity is a crucial process in cellular metabolism, facilitating the movement of glucose-6-phosphate (G6P) across cell membranes. This transport is essential for maintaining glucose homeostasis and providing a substrate for various metabolic pathways. G6P is a key intermediate in both glycolysis and gluconeogenesis, serving as a link between carbohydrate metabolism and other cellular processes. The transporter protein binds G6P on one side of the membrane, undergoes a conformational change, and releases G6P on the other side. This movement is often coupled to the movement of other molecules, like protons, to create an electrochemical gradient that drives the transport. The activity of glucose-6-phosphate transmembrane transporters is regulated by various factors, including substrate availability, cellular energy status, and hormonal signals. Disruptions in this transport activity can lead to metabolic disorders and disease states.'
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Proteins (1)

Compounds (2)