Target type: molecularfunction
Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other. [GOC:ai, GOC:mtg_transport, ISBN:0815340729]
Hexose transmembrane transporter activity refers to the movement of hexose sugars, such as glucose, fructose, and galactose, across cell membranes. This transport is essential for cells to obtain these sugars as energy sources or for other metabolic processes. Hexose transporters are transmembrane proteins that facilitate the passage of hexoses by binding to them on one side of the membrane and then releasing them on the other side. This process can occur through various mechanisms, including passive diffusion, facilitated diffusion, and active transport. Passive diffusion relies on the concentration gradient of the hexose, allowing it to move from a region of high concentration to one of low concentration. Facilitated diffusion utilizes a carrier protein to facilitate the movement of the hexose down its concentration gradient. Active transport, on the other hand, requires energy to move the hexose against its concentration gradient, from an area of low concentration to one of high concentration. The specific mechanism of hexose transport varies depending on the transporter protein involved and the cellular context. For example, glucose transporters (GLUTs) are a family of membrane proteins that facilitate the uptake of glucose into cells. These transporters are crucial for maintaining blood glucose levels and supplying energy to various tissues. Overall, hexose transmembrane transporter activity is an essential biological process that enables cells to acquire and utilize hexose sugars for various metabolic functions, including energy production, biosynthesis, and signaling.'
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Protein | Definition | Taxonomy |
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Solute carrier family 2, facilitated glucose transporter member 2 | A solute carrier family 2, facilitated glucose transporter member 2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P11168] | Homo sapiens (human) |
Solute carrier family 2, facilitated glucose transporter member 9 | A solute carrier family 2, facilitated glucose transporter member 9 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9NRM0] | Homo sapiens (human) |
Solute carrier family 2, facilitated glucose transporter member 2 | A solute carrier family 2, facilitated glucose transporter member 2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P11168] | Homo sapiens (human) |
Compound | Definition | Classes | Roles |
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orotic acid | orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6. Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE. | pyrimidinemonocarboxylic acid | Escherichia coli metabolite; metabolite; mouse metabolite |
uric acid | 6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6. 7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8. uric acid : An oxopurine that is the final oxidation product of purine metabolism. Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN. | uric acid | Escherichia coli metabolite; human metabolite; mouse metabolite |
quercetin | 7-hydroxyflavonol; pentahydroxyflavone | antibacterial agent; antineoplastic agent; antioxidant; Aurora kinase inhibitor; chelator; EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor; geroprotector; phytoestrogen; plant metabolite; protein kinase inhibitor; radical scavenger | |
myricetin | 7-hydroxyflavonol; hexahydroxyflavone | antineoplastic agent; antioxidant; cyclooxygenase 1 inhibitor; food component; geroprotector; hypoglycemic agent; plant metabolite |