peptidase complex

Definition

Target type: cellularcomponent

A protein complex which is capable of peptidase activity. [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:1689240]

Peptidase complexes are multi-protein assemblies that play crucial roles in a wide range of cellular processes, including protein degradation, signal transduction, and regulation of gene expression. These complexes are characterized by their ability to cleave peptide bonds within proteins, a process known as proteolysis. The composition and organization of peptidase complexes vary greatly, depending on the specific function and cellular context. However, they often share common features, such as the presence of catalytic subunits responsible for proteolytic activity and regulatory subunits that control complex assembly, substrate specificity, and activity. The cellular component of a peptidase complex can be described as a dynamic and intricate network of proteins, often localized to specific cellular compartments, where they interact and cooperate to achieve their biological functions. These complexes are essential for maintaining cellular homeostasis and respond to various stimuli, enabling cells to adapt to changing conditions. Specific examples of peptidase complexes include the proteasome, a large multi-subunit complex involved in protein degradation, and the signal peptidase complex, which cleaves signal peptides from newly synthesized proteins.'
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Proteins (1)

Compounds (11)