Target type: biologicalprocess
The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal. [GOC:ai]
The detection of chemical stimuli involved in sensory perception of taste is a complex process that begins with the interaction of taste molecules with specialized taste receptor cells located on the tongue, palate, and epiglottis. These taste receptor cells are grouped together in taste buds, which are embedded within the epithelium of the tongue.
There are five basic taste qualities: sweet, sour, salty, bitter, and umami. Each taste quality is detected by a different type of taste receptor cell. For example, sweet taste receptors are activated by sugars, while sour taste receptors are activated by acids.
When a taste molecule binds to its corresponding receptor, it triggers a cascade of intracellular signaling events that ultimately lead to the generation of a nerve impulse. This nerve impulse is transmitted to the brain via the facial, glossopharyngeal, and vagus nerves.
The brain then interprets the signals from the taste receptors as a particular taste sensation. The specific taste perceived is influenced by a number of factors, including the concentration of the taste molecule, the presence of other taste molecules, and the individual's genetics.
The process of taste perception is also influenced by other sensory modalities, such as smell and texture. For example, the smell of food can influence its perceived taste, and the texture of food can influence how long it remains in the mouth, which can affect the intensity of the taste.
In summary, the detection of chemical stimuli involved in sensory perception of taste is a complex process that involves the interaction of taste molecules with specialized taste receptor cells, the generation of nerve impulses, and the interpretation of these impulses by the brain. The perceived taste is influenced by a number of factors, including the concentration of the taste molecule, the presence of other taste molecules, and the individual's genetics.'
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Protein | Definition | Taxonomy |
---|---|---|
Taste receptor type 1 member 1 | A taste receptor type 1 member 1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q7RTX1] | Homo sapiens (human) |
Free fatty acid receptor 4 | A free fatty acid receptor 4 that is encoded in the genome of human. [PRO:WCB, UniProtKB:Q5NUL3] | Homo sapiens (human) |
Compound | Definition | Classes | Roles |
---|---|---|---|
lauric acid | dodecanoic acid : A straight-chain, twelve-carbon medium-chain saturated fatty acid with strong bactericidal properties; the main fatty acid in coconut oil and palm kernel oil. | medium-chain fatty acid; straight-chain saturated fatty acid | algal metabolite; antibacterial agent; plant metabolite |
12-hydroxy stearic acid | 12-hydroxy stearic acid: structure in first source 12-hydroxyoctadecanoic acid : A hydroxy fatty acid that is stearic acid bearing a hydroxy substituent at position 12. | hydroxyoctadecanoic acid; secondary alcohol | bacterial xenobiotic metabolite; plant metabolite |
16-hydroxypalmitic acid | 16-hydroxyhexadecanoic acid : An omega-hydroxy-long-chain fatty acid that is hexadecanoic acid (also known as palmitic acid) which is substituted at position 16 by a hydroxy group. It is a key monomer of cutin in the plant cuticle. | hydroxypalmitic acid; omega-hydroxy-long-chain fatty acid | plant metabolite |
12-hydroxydodecanoic acid | 12-hydroxylauric acid : A medium-chain fatty acid that is the 12-hydroxylated derivative of lauric acid. | omega-hydroxy-medium-chain fatty acid | human metabolite |
3-hydroxydodecanoic acid | 3-hydroxydodecanoic acid: RN given refers to cpd without isomeric designation 3-hydroxylauric acid : A medium-chain fatty acid that is the 3-hydroxylated derivative of lauric acid; associated with fatty acid metabolic disorders. | 3-hydroxy fatty acid; medium-chain fatty acid | |
ricinoleic acid | ricinoleic acid : A (9Z)-12-hydroxyoctadec-9-enoic acid in which the 12-hydroxy group has R-configuration.. ricinoleic acid: RN given refers to (R-(Z))-isomer; structure in Merck Index, 9th ed, #8005 | (9Z)-12-hydroxyoctadec-9-enoic acid | |
linoleic acid | linoleic acid : An octadecadienoic acid in which the two double bonds are at positions 9 and 12 and have Z (cis) stereochemistry. Linoleic Acid: A doubly unsaturated fatty acid, occurring widely in plant glycosides. It is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes. (From Stedman, 26th ed) | octadecadienoic acid; omega-6 fatty acid | algal metabolite; Daphnia galeata metabolite; plant metabolite |
alpha-linolenic acid | linolenate : A polyunsaturated fatty acid anion obtained by deprotonation of the carboxy group of either alpha- or gamma-linolenic acid. linolenic acid : A two-membered subclass of octadecatrienoic acid comprising the (9Z,12Z,15Z)- and (6Z,9Z,12Z)-isomers. Linolenic acids are nutrients essential to the formation of prostaglandins and are also used in making paints and synthetic resins. | linolenic acid; omega-3 fatty acid | micronutrient; mouse metabolite; nutraceutical |
gw9508 | GW9508: structure in first source | aromatic amine | |
lactisole | lactisole: structure in first source | ||
tak-875 | biphenyls | ||
tug-469 | TUG-469: a GPR40 agonist with antidiabetic activity; structure in first source | ||
tug-891 | GPU-028: structure in first source |