Page last updated: 2024-10-24

sensory perception of chemical stimulus

Definition

Target type: biologicalprocess

The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. [GOC:ai]

Sensory perception of chemical stimuli, also known as chemoreception, is a complex biological process involving the detection and interpretation of chemical compounds in the environment. This process is essential for survival in many organisms, enabling them to locate food, identify mates, and avoid predators.

The process typically begins with the binding of a chemical stimulus to a specific receptor protein located on the surface of sensory cells. These receptor proteins are highly specific and only bind to certain types of molecules. Once bound, the receptor protein undergoes a conformational change, triggering a cascade of intracellular signaling events.

These signaling events can involve a variety of mechanisms, including changes in membrane potential, activation of second messenger pathways, and the release of neurotransmitters. The specific signaling pathway activated depends on the type of chemoreceptor and the type of stimulus.

The signals generated by the sensory cells are then transmitted to the nervous system via sensory neurons. These neurons relay the information to specific brain regions responsible for processing and interpreting the sensory input. The brain integrates the information from different sensory modalities, including chemoreception, to generate a comprehensive perception of the environment.

Examples of chemoreception include:

- **Taste:** The perception of taste is mediated by taste receptors located on the tongue and palate. These receptors detect specific chemicals in food, allowing us to experience flavors such as sweet, sour, salty, bitter, and umami.
- **Smell:** The sense of smell, or olfaction, is mediated by olfactory receptors located in the nasal cavity. These receptors detect volatile molecules in the air, enabling us to perceive a wide range of odors.
- **Pheromone Detection:** Many animals use pheromones, chemical signals released by other individuals, for communication. Pheromone receptors are specialized chemoreceptors that detect these signals, triggering specific behavioral responses.

Chemoreception plays a crucial role in the survival of many organisms, enabling them to navigate their environment, find food and mates, and avoid predators. It is a complex and highly regulated process involving the coordinated activity of sensory cells, signaling pathways, and brain regions.'
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Proteins (3)

ProteinDefinitionTaxonomy
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLasA guanine nucleotide-binding protein G(s) subunit alpha (human), isoforms XLas-1, XLas-2, and XLas-3. [PRO:DAN, UniProtKB:Q5JWF2]Homo sapiens (human)
C5a anaphylatoxin chemotactic receptor 1A C5a anaphylatoxin chemotactic receptor 1 that is encoded in the genome of human. [PRO:WCB, UniProtKB:P21730]Homo sapiens (human)
UDP-glucuronosyltransferase 2A1A UDP-glucuronosyltransferase 2A1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P0DTE4]Homo sapiens (human)

Compounds (4)

CompoundDefinitionClassesRoles
ezogabineezogabine : A substituted aniline that is benzene-1,2,4-triamine bearing ethoxycarbonyl and 4-fluorobenzyl substituents at positions N-1 and N-4 respectively. An anticonvulsant used to treat seizures associated with epilepsy in adults.

ezogabine: structure in first source
carbamate ester;
organofluorine compound;
secondary amino compound;
substituted aniline
anticonvulsant;
potassium channel modulator
w 54011
pmx 53
ym-254890YM-254890: structure in first source