positive regulation of acute inflammatory response to non-antigenic stimulus

Definition

Target type: biologicalprocess

Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus. [GOC:add]

Positive regulation of acute inflammatory response to non-antigenic stimulus is a complex biological process involving a cascade of events initiated by the recognition of non-antigenic stimuli, such as physical injury, mechanical stress, or certain chemicals. These stimuli trigger the release of pro-inflammatory mediators, including cytokines, chemokines, and other signaling molecules, by various cell types, such as macrophages, neutrophils, and mast cells. These mediators activate and recruit immune cells to the site of injury or stress, initiating an inflammatory response characterized by vasodilation, increased vascular permeability, and the influx of immune cells. The influx of neutrophils and macrophages leads to phagocytosis and clearance of damaged cells and debris, while the release of cytokines promotes tissue repair and restoration of homeostasis. The overall process is tightly regulated to ensure an appropriate and balanced inflammatory response, preventing excessive inflammation and potential tissue damage. Notably, the specific molecular mechanisms and cellular players involved in this process can vary depending on the specific non-antigenic stimulus and the tissue context.'
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Proteins (2)

Compounds (7)