O(6)-methyldeoxyguanylic acid: incorporated into DNA by DNA polymerase I & II [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 124999 |
| CHEMBL ID | 1230511 |
| MeSH ID | M0070302 |
| Synonym |
|---|
| 63642-13-7 |
| CHEMBL1230511 |
| mdgmp |
| 9h-purin-2-amine, 9-(2-deoxy-5-o-phosphono-beta-d-erythro-pentofuranosyl)-6-methoxy- |
| o(6)-methyldeoxyguanylic acid |
| o(6)-methyldeoxyguanylic-acid |
| o(6)-methyldeoxyguanosine monophosphate |
| 6-o-methyl guanosine-5'-monophosphate |
| 9-(2-deoxy-5-o-phosphono-beta-d-erythro-pentofuranosyl)-6-methoxy-9h-purin-2-amine |
| DTXSID40979867 |
| 9-(2-deoxy-5-o-phosphonopentofuranosyl)-6-methoxy-3,9-dihydro-2h-purin-2-imine |
| Q27456489 |
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Adenosine deaminase-like protein | Homo sapiens (human) | Km | 6.0000 | 6.0000 | 6.0000 | 6.0000 | AID612651 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| nucleotide metabolic process | Adenosine deaminase-like protein | Homo sapiens (human) |
| inosine biosynthetic process | Adenosine deaminase-like protein | Homo sapiens (human) |
| adenosine catabolic process | Adenosine deaminase-like protein | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| metal ion binding | Adenosine deaminase-like protein | Homo sapiens (human) |
| N6-methyl-AMP deaminase activity | Adenosine deaminase-like protein | Homo sapiens (human) |
| adenosine deaminase activity | Adenosine deaminase-like protein | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| cytosol | Adenosine deaminase-like protein | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID612650 | Kcat/Km ratio of recombinant human ADAL1 expressed in Escherichia coli | 2011 | Journal of medicinal chemistry, Aug-25, Volume: 54, Issue:16 | Adenosine deaminase-like protein 1 (ADAL1): characterization and substrate specificity in the hydrolysis of N(6)- or O(6)-substituted purine or 2-aminopurine nucleoside monophosphates. |
| AID612651 | Activity of recombinant human ADAL1 expressed in Escherichia coli by UV-spectrophotometry | 2011 | Journal of medicinal chemistry, Aug-25, Volume: 54, Issue:16 | Adenosine deaminase-like protein 1 (ADAL1): characterization and substrate specificity in the hydrolysis of N(6)- or O(6)-substituted purine or 2-aminopurine nucleoside monophosphates. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.21) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||