Tamoxifen metabolism

Proteins (0)

Compound	Description
tamoxifen	One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM.
ici 142269	RN given refers to (Z)-isomer; structure given in first source
4-hydroxy-N-desmethyltamoxifen	metabolite of tamoxifen in human bile
adenosine 3'-phosphate-5'-phosphate
tamoxifen n-oxide
desdimethyltamoxifen
alpha-hydroxytamoxifen	structure in first source
afimoxifene
phosphoadenosine phosphosulfate	3'-Phosphoadenosine-5'-phosphosulfate. Key intermediate in the formation by living cells of sulfate esters of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate. It is formed from sulfate ion and ATP in a two-step process. This compound also is an important step in the process of sulfur fixation in plants and microorganisms.
afimoxifene