Signaling by ERBB2 TMD/JMD mutants

Proteins (9)

Protein	Synonyms	Taxonomy
Epidermal growth factor receptor	EC 2.7.10.1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1	Homo sapiens (human)
Receptor tyrosine-protein kinase erbB-2	EC 2.7.10.1; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2	Homo sapiens (human)
Heat shock protein HSP 90-alpha	EC 3.6.4.10; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38	Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1	Homo sapiens (human)
SHC-transforming protein 1	SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1	Homo sapiens (human)
Son of sevenless homolog 1	SOS-1	Homo sapiens (human)
Pro-epidermal growth factor	EGF	Homo sapiens (human)
Hsp90 co-chaperone Cdc37	Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37	Homo sapiens (human)
Erbin	Densin-180-like protein; Erbb2-interacting protein; Protein LAP2	Homo sapiens (human)

Compound	Description
adenosine diphosphate	Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Guanosine Monophosphate	A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Guanosine Diphosphate	A guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
adenosine triphosphate	An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.