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Serine Biosynthesis and Metabolism

Proteins (10)

ProteinSynonymsTaxonomy
D-3-phosphoglycerate dehydrogenasePGDH; EC 1.1.1.95; 2-oxoglutarate reductase; 1.1.1.399Escherichia coli K-12
Phosphoserine phosphatasePSP; PSPase; EC 3.1.3.3; O-phosphoserine phosphohydrolaseEscherichia coli K-12
Phosphoserine aminotransferaseEC 2.6.1.52; Phosphohydroxythreonine aminotransferase; PSATEscherichia coli K-12
Serine transporterEscherichia coli K-12
L-serine dehydratase 1SDH 1; EC 4.3.1.17; L-serine deaminase 1; L-SD1Escherichia coli K-12
Phosphonates import ATP-binding protein PhnCEC 7.3.2.2Escherichia coli K-12
Phosphonates-binding periplasmic proteinEscherichia coli K-12
L-serine dehydratase 2SDH 2; EC 4.3.1.17; L-serine deaminase 2; L-SD2Escherichia coli K-12
Threonine/serine transporter TdcCH(+)/threonine-serine symporterEscherichia coli str. K-12 substr. DH10B
PUTATIVE PSEUDOGENE: RecName: Full=Putative phosphonates transport system permease protein PhnEEscherichia coli K-12

Compounds (18)

CompoundDescription
hydronium ion
pyruvic acidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Orthophosphate
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
glutamic acidA non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.
NADH
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Coenzyme A
phosphohydroxypyruvic acid
phosphoserineThe phosphoric acid ester of serine.
dehydroalanine
alpha-ketoglutaric acid
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
serineA non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
3-phosphoglycerate
acetyl coenzyme aAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.