Page last updated: 2024-10-06

Mycothiol metabolism

Proteins (8)

ProteinSynonymsTaxonomy
Mycothione reductaseEC 1.8.1.15; Mycothiol-disulfide reductase; NADPH-dependent mycothione reductaseMycobacterium tuberculosis H37Rv
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligaseL-Cys:GlcN-Ins ligase; EC 6.3.1.13; Mycothiol ligase; MSH ligaseMycobacterium tuberculosis H37Rv
Histidinol-phosphataseHolPase; EC 3.1.3.15; Histidinol-phosphate phosphataseMycobacterium tuberculosis H37Rv
Inositol-3-phosphate synthaseIPS; EC 5.5.1.4; Myo-inositol 1-phosphate synthase; MI-1-P synthase; MIP synthaseMycobacterium tuberculosis H37Rv
D-inositol 3-phosphate glycosyltransferaseEC 2.4.1.250; N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferaseMycobacterium tuberculosis H37Rv
Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase) (LmbE protein)Mycobacterium tuberculosis
S-nitrosomycothiol reductase MscRMycobacterium tuberculosis H37Rv
Mycothiol acetyltransferaseMSH acetyltransferase; EC 2.3.1.189; Mycothiol synthaseMycobacterium tuberculosis H37Rv

Compounds (22)

CompoundDescription
diphosphoric acid
hydronium ion
Orthophosphate
inositol 1-phosphate
acetic acidProduct of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
NADH
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
formaldehydeA highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p717)
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
1-inosityl-2-acetamido-2-deoxyglucopyranoside
formic acidRN given refers to parent cpd
mycothiola glyco-inositol-cysteine found in MYCOBACTERIUM BOVIS which conjugates exogenous compounds for detoxication; it is a microbe counterpart to eucaryotic GLUTATHIONE; acted on by mycothiol disulfide reductase and mycothiol S-conjugate amidase and MDF dehydrogenase;
Uridine Diphosphate N-AcetylglucosamineServes as the biological precursor of insect chitin, of muramic acid in bacterial cell walls, and of sialic acids in mammalian glycoproteins.
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
CysteineA thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
X 14847aminoglycoside antibiotic from Micromonospora echinospora
acetyl coenzyme aAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
creolinfrom refined coal tar oils
coenzyme a