Page last updated: 2024-10-06

MicroRNA (miRNA) biogenesis

Proteins (20)

ProteinSynonymsTaxonomy
RISC-loading complex subunit TARBP2TAR RNA-binding protein 2; Trans-activation-responsive RNA-binding proteinHomo sapiens (human)
RNA 5'-monophosphate methyltransferaseEC 2.1.1.-; BCDIN3 domain-containing proteinHomo sapiens (human)
Endoribonuclease DicerEC 3.1.26.3; Helicase with RNase motif; Helicase MOIHomo sapiens (human)
GTP-binding nuclear protein RanAndrogen receptor-associated protein 24; GTPase Ran; Ras-like protein TC4; Ras-related nuclear proteinHomo sapiens (human)
DNA-directed RNA polymerase II subunit RPB1RNA polymerase II subunit B1; EC 2.7.7.6; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase III largest subunit; RNA-directed RNA polymerase II subunit RPB1; 2.7.7.48Homo sapiens (human)
Exportin-5Exp5; Ran-binding protein 21Homo sapiens (human)
Ribonuclease 3EC 3.1.26.3; Protein Drosha; Ribonuclease III; RNase III; p241Homo sapiens (human)
Microprocessor complex subunit DGCR8DiGeorge syndrome critical region 8Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC4RNA polymerases I, II, and III subunit ABC4; ABC10-alpha; DNA-directed RNA polymerase II subunit K; RNA polymerase II 7.0 kDa subunit; RPB7.0; RPB10alphaHomo sapiens (human)
DNA-directed RNA polymerase II subunit RPB4RNA polymerase II subunit B4; DNA-directed RNA polymerase II subunit D; RNA polymerase II 16 kDa subunit; RPB16Homo sapiens (human)
Interferon-inducible double-stranded RNA-dependent protein kinase activator APKR-associated protein X; PKR-associating protein X; Protein activator of the interferon-induced protein kinase; Protein kinase, interferon-inducible double-stranded RNA-dependent activatorHomo sapiens (human)
DNA-directed RNA polymerase II subunit RPB3RNA polymerase II subunit 3; RNA polymerase II subunit B3; DNA-directed RNA polymerase II 33 kDa polypeptide; RPB33; DNA-directed RNA polymerase II subunit C; RPB31Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC1RNA polymerases I, II, and III subunit ABC1; DNA-directed RNA polymerase II 23 kDa polypeptide; DNA-directed RNA polymerase II subunit E; RPB5 homolog; XAP4Homo sapiens (human)
DNA-directed RNA polymerase II subunit RPB2EC 2.7.7.6; DNA-directed RNA polymerase II 140 kDa polypeptide; DNA-directed RNA polymerase II subunit B; RNA polymerase II subunit 2; RNA polymerase II subunit B2Homo sapiens (human)
DNA-directed RNA polymerase II subunit RPB9RNA polymerase II subunit B9; DNA-directed RNA polymerase II subunit I; RNA polymerase II 14.5 kDa subunit; RPB14.5Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC3RNA polymerases I, II, and III subunit ABC3; DNA-directed RNA polymerase II subunit H; DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide; RPB17; RPB8 homolog; hRPB8Homo sapiens (human)
DNA-directed RNA polymerase II subunit RPB11-aRNA polymerase II subunit B11-a; RPB11a; DNA-directed RNA polymerase II subunit J-1; RNA polymerase II 13.3 kDa subunitHomo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC2RNA polymerases I, II, and III subunit ABC2; DNA-directed RNA polymerase II subunit F; DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide; RPABC14.4; RPB14.4; RPB6 homolog; RPC15Homo sapiens (human)
DNA-directed RNA polymerase II subunit RPB7RNA polymerase II subunit B7; DNA-directed RNA polymerase II subunit G; RNA polymerase II 19 kDa subunit; RPB19Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC5RNA polymerases I, II, and III subunit ABC5; DNA-directed RNA polymerase III subunit L; RNA polymerase II 7.6 kDa subunit; RPB7.6; RPB10 homologHomo sapiens (human)

Compounds (4)

CompoundDescription
Orthophosphate
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)