Page last updated: 2024-10-06

Malate-Aspartate Shuttle

Proteins (4)

ProteinSynonymsTaxonomy
Aspartate aminotransferase, mitochondrialmAspAT; EC 2.6.1.1; EC 2.6.1.7; Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; PlHomo sapiens (human)
Malate dehydrogenase, mitochondrialEC 1.1.1.37Homo sapiens (human)
Calcium-binding mitochondrial carrier protein Aralar1Mitochondrial aspartate glutamate carrier 1; Solute carrier family 25 member 12Homo sapiens (human)
Mitochondrial 2-oxoglutarate/malate carrier proteinOGCP; Solute carrier family 25 member 11Homo sapiens (human)

Compounds (7)

CompoundDescription
hydronium ion
glutamic acidA non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.
NADH
malic acid
alpha-ketoglutaric acid
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
oxaloacetic acidA dicarboxylic acid ketone that is an important metabolic intermediate of the CITRIC ACID CYCLE. It can be converted to ASPARTIC ACID by ASPARTATE TRANSAMINASE.