Pathways > Leucine Biosynthesis
Page last updated: 2024-10-06

Leucine Biosynthesis

Proteins (8)

ProteinSynonymsTaxonomy
2-isopropylmalate synthaseEC 2.3.3.13; Alpha-IPM synthase; Alpha-isopropylmalate synthaseEscherichia coli K-12
3-isopropylmalate dehydratase large subunitEC 4.2.1.33; Alpha-IPM isomerase; IPMI; Isopropylmalate isomeraseEscherichia coli K-12
3-isopropylmalate dehydratase small subunitEC 4.2.1.33; Alpha-IPM isomerase; IPMI; Isopropylmalate isomeraseEscherichia coli K-12
Branched-chain-amino-acid aminotransferaseBCAT; EC 2.6.1.42; Transaminase BEscherichia coli K-12
3-isopropylmalate dehydrogenaseEC 1.1.1.85; 3-IPM-DH; Beta-IPM dehydrogenase; IMDHEscherichia coli K-12
Aromatic-amino-acid aminotransferaseARAT; AROAT; EC 2.6.1.57; Beta-methylphenylalanine transaminase; 2.6.1.107Escherichia coli K-12
Lysine exporter LysOLys outward permeaseEscherichia coli K-12
D-malate dehydrogenase [decarboxylating]EC 1.1.1.83; D-malate degradation protein A; D-malate oxidaseEscherichia coli K-12

Compounds (14)

CompoundDescription
hydronium ion
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
glutamic acidA non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.
NADH
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Coenzyme A
2-oxo-3-methylvalerate
alpha-ketoglutaric acid
alpha-isopropylmalatestructure
beta-isopropylmalateRN given refers to (threo-(D)-isomer)
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
leucineAn essential branched-chain amino acid important for hemoglobin formation.
2-keto-4-methylvalerate
acetyl coenzyme aAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.