Pathways > GDNF signaling
Page last updated: 2024-10-06

GDNF signaling

Proteins (132)

ProteinSynonymsTaxonomy
mothers against decapentaplegic homolog 3 isoform 1Homo sapiens (human)
NF-kappa-B inhibitor alphaHomo sapiens (human)
estrogen receptor isoform 1Homo sapiens (human)
sodium-dependent dopamine transporterHomo sapiens (human)
hypoxia-inducible factor 1-alpha isoform 1Homo sapiens (human)
serine/threonine-protein kinase mTOR isoform 1Homo sapiens (human)
rho-associated protein kinase 1Homo sapiens (human)
calcium/calmodulin-dependent protein kinase type II subunit beta isoform 1Homo sapiens (human)
inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1Homo sapiens (human)
tyrosine-protein kinase Lyn isoform AHomo sapiens (human)
3-phosphoinositide-dependent protein kinase 1 isoform 1Homo sapiens (human)
rho-associated protein kinase 2 isoform 1Homo sapiens (human)
proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)
RAC-gamma serine/threonine-protein kinase isoform 1Homo sapiens (human)
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform 1Homo sapiens (human)
apoptosis regulator Bcl-2 isoform alphaHomo sapiens (human)
inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1Homo sapiens (human)
mitogen-activated protein kinase 14 isoform 1Homo sapiens (human)
sphingosine 1-phosphate receptor 1Homo sapiens (human)
mitogen-activated protein kinase 1Homo sapiens (human)
dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)
serine/threonine-protein kinase B-raf isoform 1Homo sapiens (human)
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)
sphingosine 1-phosphate receptor 3Homo sapiens (human)
dual specificity mitogen-activated protein kinase kinase 2Homo sapiens (human)
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform PTENHomo sapiens (human)
hepatocyte growth factor receptor isoform a preproproteinHomo sapiens (human)
tyrosine-protein kinase Fyn isoform aHomo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2Homo sapiens (human)
mitogen-activated protein kinase 8 isoform alpha2Homo sapiens (human)
glutamate decarboxylase 1 isoform GAD67Homo sapiens (human)
mitogen-activated protein kinase kinase kinase 14Homo sapiens (human)
cyclin-A2Homo sapiens (human)
myc proto-oncogene protein isoform 1Homo sapiens (human)
heat shock protein beta-1Homo sapiens (human)
glycogen synthase kinase-3 beta isoform 1Homo sapiens (human)
mitogen-activated protein kinase 3 isoform 1Homo sapiens (human)
tyrosine-protein kinase YesHomo sapiens (human)
transcription factor p65 isoform 1Homo sapiens (human)
mitogen-activated protein kinase kinase kinase 3 isoform 1Homo sapiens (human)
synaptophysinHomo sapiens (human)
ezrinHomo sapiens (human)
GTPase NRasHomo sapiens (human)
glutamate decarboxylase 2Homo sapiens (human)
forkhead box protein O3Homo sapiens (human)
forkhead box protein O1Homo sapiens (human)
CD2-associated proteinHomo sapiens (human)
B-cell CLL/lymphoma 6 member B proteinHomo sapiens (human)
amyloid-beta precursor protein isoform a precursorHomo sapiens (human)
growth factor receptor-bound protein 7 isoform bHomo sapiens (human)
neural cell adhesion molecule 1 isoform 5 precursorHomo sapiens (human)
inositol 1,4,5-trisphosphate receptor type 2Homo sapiens (human)
inositol 1,4,5-trisphosphate receptor type 3Homo sapiens (human)
mitogen-activated protein kinase 9 isoform alpha2Homo sapiens (human)
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1Homo sapiens (human)
sortilin-related receptor preproproteinHomo sapiens (human)
cyclic AMP-dependent transcription factor ATF-1Homo sapiens (human)
CCAAT/enhancer-binding protein beta isoform aHomo sapiens (human)
GDNF family receptor alpha-1 isoform a preproproteinHomo sapiens (human)
LIM/homeobox protein Lhx1Homo sapiens (human)
potassium voltage-gated channel subfamily D member 2 precursorHomo sapiens (human)
docking protein 4 isoform 1Homo sapiens (human)
ras-related C3 botulinum toxin substrate 1 isoform Rac1bHomo sapiens (human)
protocadherin alpha-4 isoform 1 precursorHomo sapiens (human)
protocadherin gamma-B7 isoform 1 precursorHomo sapiens (human)
phosphatidylinositol 3-kinase regulatory subunit alpha isoform 1Homo sapiens (human)
integrin beta-3 precursorHomo sapiens (human)
mothers against decapentaplegic homolog 2 isoform 1Homo sapiens (human)
ras-related protein Rap-1A precursorHomo sapiens (human)
nuclear factor NF-kappa-B p100 subunit isoform aHomo sapiens (human)
integrin alpha-6 isoform a preproproteinHomo sapiens (human)
paxillin isoform 2Homo sapiens (human)
ETS domain-containing protein Elk-1 isoform aHomo sapiens (human)
SHC-transforming protein 1 isoform 3Homo sapiens (human)
guanine nucleotide exchange factor VAV2 isoform 1Homo sapiens (human)
inositol 1,4,5-trisphosphate receptor type 1 isoform 3Homo sapiens (human)
breast cancer anti-estrogen resistance protein 1 isoform 1Homo sapiens (human)
bcl-2-like protein 2Homo sapiens (human)
G1/S-specific cyclin-E1 isoform 1Homo sapiens (human)
ribosomal protein S6 kinase beta-1 isoform bHomo sapiens (human)
fibroblast growth factor receptor substrate 2Homo sapiens (human)
protocadherin Fat 4 isoform 1 precursorHomo sapiens (human)
N-myc proto-oncogene protein isoform 1Homo sapiens (human)
cAMP-dependent protein kinase catalytic subunit alpha isoform 3Homo sapiens (human)
agrin isoform 1 precursorHomo sapiens (human)
TGF-beta receptor type-1 isoform 3 precursorHomo sapiens (human)
AP-2 complex subunit mu isoform cHomo sapiens (human)
cAMP-dependent protein kinase type II-alpha regulatory subunit isoform aHomo sapiens (human)
rap1 GTPase-activating protein 1 isoform 4Homo sapiens (human)
tyrosine-protein phosphatase non-receptor type 11 isoform 3Homo sapiens (human)
focal adhesion kinase 1 isoform 1Homo sapiens (human)
RAF proto-oncogene serine/threonine-protein kinase isoform aHomo sapiens (human)
SH2B adapter protein 2 isoform 2Homo sapiens (human)
growth factor receptor-bound protein 10 isoform fHomo sapiens (human)
docking protein 1 isoform aHomo sapiens (human)
GDNF family receptor alpha-2 isoform a preproproteinHomo sapiens (human)
GDNF family receptor alpha-3 preproproteinHomo sapiens (human)
transforming protein RhoA isoform 1 precursorHomo sapiens (human)
cadherin-2 isoform 1 preproproteinHomo sapiens (human)
desmoglein-2 preproproteinHomo sapiens (human)
growth factor receptor-bound protein 2 isoform 1Homo sapiens (human)
integrin alpha-3 preproproteinHomo sapiens (human)
integrin alpha-5 precursorHomo sapiens (human)
integrin beta-1 isoform 1A precursorHomo sapiens (human)
myocyte-specific enhancer factor 2C isoform 1Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform aHomo sapiens (human)
ras GTPase-activating protein 1 isoform 1Homo sapiens (human)
vascular endothelial growth factor A isoform bHomo sapiens (human)
calreticulin precursorHomo sapiens (human)
ETS translocation variant 5Homo sapiens (human)
rab GTPase-binding effector protein 1 isoform 1Homo sapiens (human)
PDZ and LIM domain protein 7 isoform 1Homo sapiens (human)
protein sprouty homolog 2Homo sapiens (human)
cytoplasmic protein NCK1 isoform 1Homo sapiens (human)
synapsin-1 isoform IaHomo sapiens (human)
E3 ubiquitin-protein ligase CBL-C isoform 1Homo sapiens (human)
neuronal calcium sensor 1 isoform 1Homo sapiens (human)
leucine-rich repeats and immunoglobulin-like domains protein 1 isoform 1 precursorHomo sapiens (human)
calcium/calmodulin-dependent protein kinase type II subunit alpha isoform 1Homo sapiens (human)
adapter molecule crk isoform aHomo sapiens (human)
regulatory-associated protein of mTOR isoform 1Homo sapiens (human)
proto-oncogene tyrosine-protein kinase receptor Ret isoform a precursorHomo sapiens (human)
G2/mitotic-specific cyclin-B1 isoform 1Homo sapiens (human)
GRB2-associated-binding protein 2 isoform aHomo sapiens (human)
cyclic AMP-responsive element-binding protein 1 isoform BHomo sapiens (human)
transcription factor Sp1 isoform aHomo sapiens (human)
mitogen-activated protein kinase 7 isoform 1Homo sapiens (human)
dual specificity mitogen-activated protein kinase kinase 5 isoform AHomo sapiens (human)
14-3-3 protein zeta/deltaHomo sapiens (human)
docking protein 6Homo sapiens (human)
sphingosine kinase 1 isoform 2Homo sapiens (human)
GRB2-associated-binding protein 1 isoform aHomo sapiens (human)

Compounds (7)

CompoundDescription
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
G(M1) GangliosideA specific monosialoganglioside that accumulates abnormally within the nervous system due to a deficiency of GM1-b-galactosidase, resulting in GM1 gangliosidosis.
inositol 1,4,5-trisphosphateIntracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.
sphingosineAn amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed)
sphingosine 1-phosphateRN given refers to (R-(R*,S*-(E)))-isomer; RN for cpd without isomeric designation not available 8/89
Phosphatidylinositol 4,5-DiphosphateA phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994)
phosphatidylinositol 3,4,5-triphosphate
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