| Protein | Synonyms | Taxonomy |
|---|---|---|
| Renin | EC 3.4.23.15; Angiotensinogenase | Homo sapiens (human) |
| Angiotensinogen | Serpin A8 | Homo sapiens (human) |
| Angiotensin-converting enzyme | ACE; EC 3.2.1.-; EC 3.4.15.1; Dipeptidyl carboxypeptidase I; Kininase II | Homo sapiens (human) |
| Compound | Description |
|---|---|
| angiotensin ii | An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS. |
| captopril | A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin. |
| angiotensin i, ile(5)- |