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Ascorbate Biosynthesis

Proteins (4)

ProteinSynonymsTaxonomy
Beta-glucuronidaseEC 3.2.1.31Mus musculus (house mouse)
RegucalcinRC; Gluconolactonase; GNL; 3.1.1.17; Senescence marker protein 30; SMP-30Mus musculus (house mouse)
Aldo-keto reductase family 1 member A1EC 1.1.1.2; EC 1.1.1.33; EC 1.1.1.372; EC 1.1.1.54; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; 1.1.1.19; Glucuronolactone reductase; 1.1.1.20Mus musculus (house mouse)
L-gulonolactone oxidaseLGO; EC 1.1.3.8; L-gulono-gamma-lactone oxidase; GLOMus musculus (house mouse)

Compounds (12)

CompoundDescription
hydronium ion
ascorbic acidA six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
uridine diphosphate glucuronic acidA nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones.
gulonolactone, (L)-isomer
glucuronic acidA sugar acid formed by the oxidation of the C-6 carbon of GLUCOSE. In addition to being a key intermediate metabolite of the uronic acid pathway, glucuronic acid also plays a role in the detoxification of certain drugs and toxins by conjugating with them to form GLUCURONIDES.
gulonic acidRN given refers to (D)-isomer
creolinfrom refined coal tar oils
Glucuronic AcidA sugar acid formed by the oxidation of the C-6 carbon of GLUCOSE. In addition to being a key intermediate metabolite of the uronic acid pathway, glucuronic acid also plays a role in the detoxification of certain drugs and toxins by conjugating with them to form GLUCURONIDES.