Page last updated: 2024-10-24

verapamil and Keloid

verapamil has been researched along with Keloid in 33 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Keloid: A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.

Research Excerpts

ExcerptRelevanceReference
"These findings suggest that the combination of verapamil and triamcinolone provides a more effective treatment for keloids, thereby highlighting the potential of verapamil in scar reduction."9.69Comparing intralesional triamcinolone and verapamil-triamcinolone injections in keloids: A single-blinded randomised clinical trial. ( Esmailzadeh, M; Hadadi, R; Haghani-Dogahe, Z; Mobayen, M, 2023)
"Concerning the treatment of keloids and hypertrophic scars, TAC was more effective than verapamil for improving vascularity; TAC was superior to verapamil in improving height within 9 weeks of treatment; TAC produced superior result for improving pliability within 18 weeks of treatment, whereas verapamil produced superior result between 18 and 24 weeks of treatment."9.41Efficacy and Safety of Verapamil Versus Triamcinolone Acetonide in Treating Keloids and Hypertrophic Scars: A Systematic Review and Meta-Analysis. ( Li, X; Zhang, W, 2023)
"This is a prospective, randomized study of intralesional injection of verapamil and triamcinolone in keloids conducted in the Burns and Plastic unit of a tertiary hospital."9.41A comparison of intralesional verapamil and triamcinolone monotherapy in the treatment of keloids in an African population. ( Belie, MF; Belie, O; Mofikoya, BO; T Omidiji, OA; Ugburo, AO, 2021)
"Our results did not support verapamil's capability in treatment of keloid nor hypertrophic scars."9.27Comparison of intralesional verapamil versus intralesional corticosteroids in treatment of keloids and hypertrophic scars: A randomized controlled trial. ( Abedini, R; Mahmoudi, HR; Nasimi, M; Sasani, P; Shadlou, Z; Teymourpour, A, 2018)
"A double-blind randomized controlled trial with a paired split-scar design compared verapamil, an L-type Ca2+ channel antagonist, and triamcinolone for prevention of keloid recurrence after excision."9.22Verapamil is Less Effective than Triamcinolone for Prevention of Keloid Scar Recurrence After Excision in a Randomized Controlled Trial. ( Alghamdi, M; Danielsen, PL; Fear, MW; Gankande, TU; Hool, LC; Manzur, M; Rea, SM; Stevenson, AW; Viola, HM; Wallace, HJ; Wood, FM, 2016)
"The aim of this study was to conduct a meta-analysis of the effectiveness and safety of verapamil and TAC in the treatment of HSs and keloids."9.12Comparing the Efficacy and Safety of Intralesional Verapamil With Intralesional Triamcinolone Acetonide in Treatment of Hypertrophic Scars and Keloids: A Meta-Analysis of Randomized Controlled Trials. ( Bi, H; Gu, L; Qin, Z; Wang, P; Wang, Q, 2021)
"TAC may be beneficial for the short-term treatment of hypertrophic scars and keloids; however, 5-FU, 5-FU+TAC, and verapamil may produce superior results for medium- and long-term treatments."9.12The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis. ( Li, Y; Wei, X; Zhuang, Z, 2021)
"These findings suggest that verapamil hydrochloride is an effective tool for the prevention and therapy of keloids."9.10Prevention and treatment of keloids with intralesional verapamil. ( Baroni, A; Brongo, S; D'Andrea, F; Ferraro, G, 2002)
"It appears that TAC is more effective than verapamil for improving scar pliability and vascularity in keloids and hypertrophic scars after 3 weeks of treatment."9.05The Safety and Efficacy of Intralesional Verapamil Versus Intralesional Triamcinolone Acetonide for Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis. ( Fu, ZH; Guo, GH; Jiang, ZY; Liao, XC; Liu, MZ; Min, DH, 2020)
"Thirty-one patients with 43 keloids were treated with IL verapamil at 3-week intervals until reaching complete flattening of the lesion or for a maximum of 6 sessions."8.02Intralesional verapamil in the treatment of keloids: A clinical, histopathological, and immunohistochemical study. ( Abou-Taleb, DAE; Badary, DM, 2021)
"Combined fractional CO2 laser and topical 5-FU or verapamil hydrochloride offer a safe therapy for HTSs and keloids."7.91The Efficacy of Combining Fractional Carbon Dioxide Laser With Verapamil Hydrochloride or 5-Fluorouracil in the Treatment of Hypertrophic Scars and Keloids: A Clinical and Immunohistochemical Study. ( Abd El Azez, TA; Abdel Rahman, SH; Hussein, MS; Sabry, HH; Sanad, RR, 2019)
"Keloids and hypertrophic scars are harmful to physical and psychological health."6.72Comparative efficacy and safety of verapamil and triamcinolone in keloid and hypertrophic scar treatment: a meta-analysis. ( An, P; Kuang, J; Li, W, 2021)
" Although triamcinolone acetonide (TAC) is one of the most common and effective treatments for keloids and hypertrophic scars, TAC is not effective in some patients, and some may even experience adverse outcomes."6.66Efficacy and safety of verapamil vs triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis. ( Deng, Z; Liu, L; Liu, R; Yang, B; Zhao, X, 2020)
"These findings suggest that the combination of verapamil and triamcinolone provides a more effective treatment for keloids, thereby highlighting the potential of verapamil in scar reduction."5.69Comparing intralesional triamcinolone and verapamil-triamcinolone injections in keloids: A single-blinded randomised clinical trial. ( Esmailzadeh, M; Hadadi, R; Haghani-Dogahe, Z; Mobayen, M, 2023)
"Verapamil has shown a great potential in the management of keloid and hypertrophic scars."5.43Role of verapamil in preventing and treating hypertrophic scars and keloids. ( Cen, Y; Chen, J; Li, Z; Mao, Y; Wang, R; Zhang, Z, 2016)
"Concerning the treatment of keloids and hypertrophic scars, TAC was more effective than verapamil for improving vascularity; TAC was superior to verapamil in improving height within 9 weeks of treatment; TAC produced superior result for improving pliability within 18 weeks of treatment, whereas verapamil produced superior result between 18 and 24 weeks of treatment."5.41Efficacy and Safety of Verapamil Versus Triamcinolone Acetonide in Treating Keloids and Hypertrophic Scars: A Systematic Review and Meta-Analysis. ( Li, X; Zhang, W, 2023)
"This is a prospective, randomized study of intralesional injection of verapamil and triamcinolone in keloids conducted in the Burns and Plastic unit of a tertiary hospital."5.41A comparison of intralesional verapamil and triamcinolone monotherapy in the treatment of keloids in an African population. ( Belie, MF; Belie, O; Mofikoya, BO; T Omidiji, OA; Ugburo, AO, 2021)
"Our results did not support verapamil's capability in treatment of keloid nor hypertrophic scars."5.27Comparison of intralesional verapamil versus intralesional corticosteroids in treatment of keloids and hypertrophic scars: A randomized controlled trial. ( Abedini, R; Mahmoudi, HR; Nasimi, M; Sasani, P; Shadlou, Z; Teymourpour, A, 2018)
"Intralesional triamcinolone acetonide, intralesional triamcinolone acetonide with hyaluronidase, and intralesional radiofrequency with triamcinolone acetonide are effective modalities for the treatment of keloids."5.27A comparative study of various modalities in the treatment of keloids. ( Aggarwal, A; Raghukumar, S; Ravikumar, BC; Vinay, KN; Yashovardhana, DP, 2018)
"A double-blind randomized controlled trial with a paired split-scar design compared verapamil, an L-type Ca2+ channel antagonist, and triamcinolone for prevention of keloid recurrence after excision."5.22Verapamil is Less Effective than Triamcinolone for Prevention of Keloid Scar Recurrence After Excision in a Randomized Controlled Trial. ( Alghamdi, M; Danielsen, PL; Fear, MW; Gankande, TU; Hool, LC; Manzur, M; Rea, SM; Stevenson, AW; Viola, HM; Wallace, HJ; Wood, FM, 2016)
"The aim of this study was to conduct a meta-analysis of the effectiveness and safety of verapamil and TAC in the treatment of HSs and keloids."5.12Comparing the Efficacy and Safety of Intralesional Verapamil With Intralesional Triamcinolone Acetonide in Treatment of Hypertrophic Scars and Keloids: A Meta-Analysis of Randomized Controlled Trials. ( Bi, H; Gu, L; Qin, Z; Wang, P; Wang, Q, 2021)
"TAC may be beneficial for the short-term treatment of hypertrophic scars and keloids; however, 5-FU, 5-FU+TAC, and verapamil may produce superior results for medium- and long-term treatments."5.12The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis. ( Li, Y; Wei, X; Zhuang, Z, 2021)
"These findings suggest that verapamil hydrochloride is an effective tool for the prevention and therapy of keloids."5.10Prevention and treatment of keloids with intralesional verapamil. ( Baroni, A; Brongo, S; D'Andrea, F; Ferraro, G, 2002)
"It appears that TAC is more effective than verapamil for improving scar pliability and vascularity in keloids and hypertrophic scars after 3 weeks of treatment."5.05The Safety and Efficacy of Intralesional Verapamil Versus Intralesional Triamcinolone Acetonide for Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis. ( Fu, ZH; Guo, GH; Jiang, ZY; Liao, XC; Liu, MZ; Min, DH, 2020)
"Intralesional triamcinolone is a gold standard in treating the keloids in comparison with its effectiveness versus intralesional 5-fluorouracil intralesional verapamil and intralesional platelet-rich plasma."4.12Assessment of various intralesional injections in keloid: comparative analysis. ( Albalat, W; Khattab, F; Nabil, S, 2022)
"Thirty-one patients with 43 keloids were treated with IL verapamil at 3-week intervals until reaching complete flattening of the lesion or for a maximum of 6 sessions."4.02Intralesional verapamil in the treatment of keloids: A clinical, histopathological, and immunohistochemical study. ( Abou-Taleb, DAE; Badary, DM, 2021)
"Combined fractional CO2 laser and topical 5-FU or verapamil hydrochloride offer a safe therapy for HTSs and keloids."3.91The Efficacy of Combining Fractional Carbon Dioxide Laser With Verapamil Hydrochloride or 5-Fluorouracil in the Treatment of Hypertrophic Scars and Keloids: A Clinical and Immunohistochemical Study. ( Abd El Azez, TA; Abdel Rahman, SH; Hussein, MS; Sabry, HH; Sanad, RR, 2019)
"Keloids are pathologic scars that pose a significant functional and cosmetic burden."3.01Keloid treatments: an evidence-based systematic review of recent advances. ( Kundu, RV; Kwan, KR; Miller, CH; Pontes, D; Poondru, S; Walsh, LA; Wu, E, 2023)
"Different approaches are used aiming to improve these scars, including intralesional corticosteroids, surgery and more recently, laser therapy."2.82Laser therapy for treating hypertrophic and keloid scars. ( da Silva, CA; da Silva, EM; Kuczynski, U; Leszczynski, R; Pinto, ACPN, 2022)
"Keloids and hypertrophic scars are harmful to physical and psychological health."2.72Comparative efficacy and safety of verapamil and triamcinolone in keloid and hypertrophic scar treatment: a meta-analysis. ( An, P; Kuang, J; Li, W, 2021)
" Although triamcinolone acetonide (TAC) is one of the most common and effective treatments for keloids and hypertrophic scars, TAC is not effective in some patients, and some may even experience adverse outcomes."2.66Efficacy and safety of verapamil vs triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis. ( Deng, Z; Liu, L; Liu, R; Yang, B; Zhao, X, 2020)
"To provide a comprehensive evidence-based review of current evidence on mechanism of action, efficacy, and adverse events of calcium antagonists in treatment of hypertrophic scars and keloids."2.52Mechanism of Action, Efficacy, and Adverse Events of Calcium Antagonists in Hypertrophic Scars and Keloids: A Systematic Review. ( Piatkowski de Grzymala, A; van der Hulst, R; Verhiel, S, 2015)
"Keloids are special type of skin lesions arising from sites of previous trauma."2.43[Therapeutic problems connected with keloid treatment--new treatment possibilities]. ( Brudnik, U; Podolec-Rubiś, M; Wojas-Pelc, A, 2006)
"The formation of hypertrophic scaring (HSc) is an abnormal wound-healing response."1.46A Comparison of Gene Expression of Decorin and MMP13 in Hypertrophic Scars Treated With Calcium Channel Blocker, Steroid, and Interferon: A Human-Scar-Carrying Animal Model Study. ( Chuang, SS; Hsiao, YC; Yang, JY; Yang, SY, 2017)
"Verapamil has shown a great potential in the management of keloid and hypertrophic scars."1.43Role of verapamil in preventing and treating hypertrophic scars and keloids. ( Cen, Y; Chen, J; Li, Z; Mao, Y; Wang, R; Zhang, Z, 2016)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.03)18.2507
2000's5 (15.15)29.6817
2010's12 (36.36)24.3611
2020's15 (45.45)2.80

Authors

AuthorsStudies
Leszczynski, R1
da Silva, CA1
Pinto, ACPN1
Kuczynski, U1
da Silva, EM1
Zhang, W1
Li, X2
Walsh, LA1
Wu, E1
Pontes, D1
Kwan, KR1
Poondru, S1
Miller, CH1
Kundu, RV1
Haghani-Dogahe, Z1
Hadadi, R1
Esmailzadeh, M1
Mobayen, M1
Teplyi, V1
Grebchenko, K1
Jiang, ZY1
Liao, XC1
Liu, MZ1
Fu, ZH1
Min, DH1
Guo, GH1
Liu, R1
Yang, B1
Deng, Z1
Liu, L1
Zhao, X1
Abou-Taleb, DAE1
Badary, DM1
Ahuja, RB2
Chatterjee, P2
Wang, P2
Gu, L2
Bi, H2
Qin, Z2
Wang, Q1
Walsh, M1
Zhuang, Z1
Li, Y1
Wei, X1
Albalat, W1
Nabil, S1
Khattab, F1
Kuang, J1
An, P1
Li, W1
Belie, O1
Ugburo, AO1
Mofikoya, BO1
T Omidiji, OA1
Belie, MF1
Abedini, R1
Sasani, P1
Mahmoudi, HR1
Nasimi, M1
Teymourpour, A1
Shadlou, Z1
Aggarwal, A1
Ravikumar, BC1
Vinay, KN1
Raghukumar, S1
Yashovardhana, DP1
Sabry, HH1
Abdel Rahman, SH1
Hussein, MS1
Sanad, RR1
Abd El Azez, TA1
Ledon, JA1
Savas, J1
Franca, K1
Chacon, A1
Nouri, K1
Boggio, RF1
Boggio, LF1
Galvão, BL1
Machado-Santelli, GM1
Wang, R1
Mao, Y1
Zhang, Z1
Li, Z1
Chen, J1
Cen, Y1
Verhiel, S1
Piatkowski de Grzymala, A1
van der Hulst, R1
Danielsen, PL1
Rea, SM1
Wood, FM1
Fear, MW1
Viola, HM1
Hool, LC1
Gankande, TU1
Alghamdi, M1
Stevenson, AW1
Manzur, M1
Wallace, HJ1
Yang, SY1
Yang, JY1
Hsiao, YC1
Chuang, SS1
Alexandrescu, D1
Fabi, S1
Yeh, LC1
Fitzpatrick, RE1
Goldman, MP1
Juckett, G1
Hartman-Adams, H1
Giugliano, G1
Pasquali, D1
Notaro, A1
Brongo, S2
Nicoletti, G1
D'Andrea, F2
Bellastella, A1
Sinisi, AA1
Skaria, AM1
Brudnik, U1
Podolec-Rubiś, M1
Wojas-Pelc, A1
Lawrence, WT1
Ferraro, G1
Baroni, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intra-lesional ACE Inhibitor for Treatment of Hypertrophic Scars[NCT05259137]Phase 2/Phase 330 participants (Anticipated)Interventional2023-08-31Not yet recruiting
Assessing and Improving Patient Knowledge About Keloids[NCT01176877]40 participants (Actual)Interventional2010-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

To Assess the Impact of an Educational Lecture on Knowledge About Keloid Scars by Comparing Mean Scores Between Knowledge Assessment Questionnaires Administered Before an Educational Lecture and Immediately After an Educational Lecture

All subjects completed a written questionnaire to assess knowledge about keloid scars before an educational lecture about keloids, immediately after the educational lecture about keloids, and 3 months after the educational lecture about keloids. This written questionnaire to assess knowledge about keloid scars contained 19 questions related to risk factors for developing keloid scars, keloid scar prevention, and keloid scar treatment. A correct response to a question was awarded 1 point and all correct responses were summed to achieve a total score. Possible total score ranged from 0 to 19. A score of 0 is associated with worse knowledge about keloid scars and a score of 19 is associated with better knowledge about keloid scars. (NCT01176877)
Timeframe: immediately before and after a 5 minute educational lecture

Interventionscore on a scale (Mean)
Pre-educational lecture scoreImmediate post-educational lecture score
Keloid Scar12.918.3

To Assess the Impact of an Educational Lecture on Long-term Knowledge Retention About Keloid Scars by Comparing Mean Scores Between Knowledge Assessment Questionnaires Administered Before an Educational Lecture and 3 Months After an Educational Lecture

All subjects completed a written questionnaire to assess knowledge about keloid scars before an educational lecture about keloids, immediately after the educational lecture about keloids, and 3 months after the educational lecture about keloids. This written questionnaire to assess knowledge about keloid scars contained 19 questions related to risk factors for developing keloid scars, keloid scar prevention, and keloid scar treatment. A correct response to a question was awarded 1 point and all correct responses were summed to achieve a total score. Possible total score ranged from 0 to 19. A score of 0 is associated with worse knowledge about keloid scars and a score of 19 is associated with better knowledge about keloid scars. (NCT01176877)
Timeframe: before and 3 months after a 5 minute educational lecture

Interventionscore on a scale (Mean)
Pre-educational lecture score3 months post-educational lecture score
Keloid Scars13.216.8

Reviews

13 reviews available for verapamil and Keloid

ArticleYear
Laser therapy for treating hypertrophic and keloid scars.
    The Cochrane database of systematic reviews, 2022, 09-26, Volume: 9

    Topics: Adrenal Cortex Hormones; Adult; Aluminum; Atrophy; Carbon Dioxide; Child; Cicatrix, Hypertrophic; Di

2022
Efficacy and Safety of Verapamil Versus Triamcinolone Acetonide in Treating Keloids and Hypertrophic Scars: A Systematic Review and Meta-Analysis.
    Aesthetic plastic surgery, 2023, Volume: 47, Issue:1

    Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Randomized Controlled Trials as T

2023
Keloid treatments: an evidence-based systematic review of recent advances.
    Systematic reviews, 2023, 03-14, Volume: 12, Issue:1

    Topics: Adrenal Cortex Hormones; Fluorouracil; Humans; Keloid; Prospective Studies; Treatment Outcome; Verap

2023
The Safety and Efficacy of Intralesional Verapamil Versus Intralesional Triamcinolone Acetonide for Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis.
    Advances in skin & wound care, 2020, Volume: 33, Issue:4

    Topics: Calcium Channel Blockers; Cicatrix, Hypertrophic; Glucocorticoids; Humans; Injections, Intralesional

2020
Efficacy and safety of verapamil vs triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis.
    Dermatologic therapy, 2020, Volume: 33, Issue:4

    Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Triamcinolone Acetonide; Verapami

2020
Comparing the Efficacy and Safety of Intralesional Verapamil With Intralesional Triamcinolone Acetonide in Treatment of Hypertrophic Scars and Keloids: A Meta-Analysis of Randomized Controlled Trials.
    Aesthetic surgery journal, 2021, 05-18, Volume: 41, Issue:6

    Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Randomized Controlled Trials as T

2021
The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis.
    Burns : journal of the International Society for Burn Injuries, 2021, Volume: 47, Issue:5

    Topics: Atrophy; Burns; Cicatrix, Hypertrophic; Culture Media; Fluorouracil; Humans; Injections, Intralesion

2021
Comparative efficacy and safety of verapamil and triamcinolone in keloid and hypertrophic scar treatment: a meta-analysis.
    Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2021, Feb-17, Volume: 23, Issue:1-2

    Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Treatment Outcome; Triamcinolone

2021
Intralesional treatment for keloids and hypertrophic scars: a review.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2013, Volume: 39, Issue:12

    Topics: Adrenal Cortex Hormones; Antibiotics, Antineoplastic; Antimetabolites; Bleomycin; Calcium Channel Bl

2013
Mechanism of Action, Efficacy, and Adverse Events of Calcium Antagonists in Hypertrophic Scars and Keloids: A Systematic Review.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2015, Volume: 41, Issue:12

    Topics: Calcium Channel Blockers; Cicatrix, Hypertrophic; Humans; Keloid; Verapamil

2015
Comparative Results in Treatment of Keloids With Intralesional 5-FU/Kenalog, 5-FU/Verapamil, Enalapril Alone,Verapamil Alone, and Laser: A Case Report and Review of the Literature.
    Journal of drugs in dermatology : JDD, 2016, Nov-01, Volume: 15, Issue:11

    Topics: Adult; Drug Therapy, Combination; Enalapril; Fluorouracil; Humans; Injections, Intralesional; Keloid

2016
Management of keloids and hypertrophic scars.
    American family physician, 2009, Aug-01, Volume: 80, Issue:3

    Topics: Bleomycin; Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Glucocorticoids; Humans; Keloid; Recur

2009
Management of keloids and hypertrophic scars.
    American family physician, 2009, Aug-01, Volume: 80, Issue:3

    Topics: Bleomycin; Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Glucocorticoids; Humans; Keloid; Recur

2009
Management of keloids and hypertrophic scars.
    American family physician, 2009, Aug-01, Volume: 80, Issue:3

    Topics: Bleomycin; Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Glucocorticoids; Humans; Keloid; Recur

2009
Management of keloids and hypertrophic scars.
    American family physician, 2009, Aug-01, Volume: 80, Issue:3

    Topics: Bleomycin; Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Glucocorticoids; Humans; Keloid; Recur

2009
[Therapeutic problems connected with keloid treatment--new treatment possibilities].
    Przeglad lekarski, 2006, Volume: 63, Issue:9

    Topics: Cicatrix, Hypertrophic; Dermatologic Agents; Fibroblasts; Humans; Keloid; Mitomycin; Scleroderma, Lo

2006

Trials

8 trials available for verapamil and Keloid

ArticleYear
Comparing intralesional triamcinolone and verapamil-triamcinolone injections in keloids: A single-blinded randomised clinical trial.
    International wound journal, 2023, Volume: 20, Issue:10

    Topics: Cicatrix, Hypertrophic; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Treatment Outcom

2023
THE USAGE OF RADIOFREQUENCY ABLATION FOR TREATMENT OF KELOIDS AND HYPERTROPHIC SCARS.
    Problemy radiatsiinoi medytsyny ta radiobiolohii, 2019, Volume: 24

    Topics: Adult; Catheter Ablation; Cicatrix, Hypertrophic; Combined Modality Therapy; Female; Fluorouracil; H

2019
A comparison of intralesional verapamil and triamcinolone monotherapy in the treatment of keloids in an African population.
    Nigerian journal of clinical practice, 2021, Volume: 24, Issue:7

    Topics: Glucocorticoids; Humans; Keloid; Prospective Studies; Treatment Outcome; Triamcinolone Acetonide; Ve

2021
Comparison of intralesional verapamil versus intralesional corticosteroids in treatment of keloids and hypertrophic scars: A randomized controlled trial.
    Burns : journal of the International Society for Burn Injuries, 2018, Volume: 44, Issue:6

    Topics: Adolescent; Adult; Calcium Channel Blockers; Cicatrix, Hypertrophic; Factor Analysis, Statistical; F

2018
A comparative study of various modalities in the treatment of keloids.
    International journal of dermatology, 2018, Volume: 57, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Agents; Calcium Channel Blockers; Combined Modality Therapy; Drug

2018
Comparative efficacy of intralesional verapamil hydrochloride and triamcinolone acetonide in hypertrophic scars and keloids.
    Burns : journal of the International Society for Burn Injuries, 2014, Volume: 40, Issue:4

    Topics: Adolescent; Adult; Calcium Channel Blockers; Cicatrix, Hypertrophic; Female; Glucocorticoids; Humans

2014
Verapamil is Less Effective than Triamcinolone for Prevention of Keloid Scar Recurrence After Excision in a Randomized Controlled Trial.
    Acta dermato-venereologica, 2016, Aug-23, Volume: 96, Issue:6

    Topics: Adolescent; Adult; Cicatrix; Double-Blind Method; Female; Glucocorticoids; Humans; Injections, Intra

2016
Prevention and treatment of keloids with intralesional verapamil.
    Dermatology (Basel, Switzerland), 2002, Volume: 204, Issue:1

    Topics: Administration, Topical; Adult; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Inject

2002

Other Studies

12 other studies available for verapamil and Keloid

ArticleYear
Intralesional verapamil in the treatment of keloids: A clinical, histopathological, and immunohistochemical study.
    Journal of cosmetic dermatology, 2021, Volume: 20, Issue:1

    Topics: Glucocorticoids; Humans; Injections, Intralesional; Keloid; Pain; Treatment Outcome; Verapamil

2021
Response to Letter to the Editor: Comments on "Comparative efficacy of intralesional verapamil hydrochloride and triamcinolone acetonide in hypertrophic scars and keloids".
    Burns : journal of the International Society for Burn Injuries, 2020, Volume: 46, Issue:7

    Topics: Burns; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Triamcinolone Acetonide; V

2020
Comments on "Comparative efficacy of intralesional verapamil hydrochloride and triamcinolone acetonide in hypertrophic scars and keloids".
    Burns : journal of the International Society for Burn Injuries, 2020, Volume: 46, Issue:7

    Topics: Burns; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Triamcinolone Acetonide; V

2020
Commentary on: Comparing the Efficacy and Safety of Intralesional Verapamil With Intralesional Triamcinolone Acetonide in Treatment of Hypertrophic Scars and Keloids: A Meta-Analysis of Randomized Controlled Trials.
    Aesthetic surgery journal, 2021, 05-18, Volume: 41, Issue:6

    Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Randomized Controlled Trials as T

2021
Assessment of various intralesional injections in keloid: comparative analysis.
    The Journal of dermatological treatment, 2022, Volume: 33, Issue:4

    Topics: Fluorouracil; Humans; Injections, Intralesional; Keloid; Treatment Outcome; Triamcinolone Acetonide;

2022
The Efficacy of Combining Fractional Carbon Dioxide Laser With Verapamil Hydrochloride or 5-Fluorouracil in the Treatment of Hypertrophic Scars and Keloids: A Clinical and Immunohistochemical Study.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2019, Volume: 45, Issue:4

    Topics: Administration, Topical; Cicatrix, Hypertrophic; Combined Modality Therapy; Dose Fractionation, Radi

2019
Topical verapamil as a scar modulator.
    Aesthetic plastic surgery, 2014, Volume: 38, Issue:5

    Topics: Abdominoplasty; Administration, Topical; Adult; Aged; Calcium Channel Blockers; Cicatrix, Hypertroph

2014
Role of verapamil in preventing and treating hypertrophic scars and keloids.
    International wound journal, 2016, Volume: 13, Issue:4

    Topics: Cicatrix, Hypertrophic; Databases, Factual; Humans; Keloid; Verapamil

2016
A Comparison of Gene Expression of Decorin and MMP13 in Hypertrophic Scars Treated With Calcium Channel Blocker, Steroid, and Interferon: A Human-Scar-Carrying Animal Model Study.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2017, Volume: 43 Suppl 1

    Topics: Adolescent; Adult; Animals; Burns; Calcium Channel Blockers; Child; Child, Preschool; Cicatrix; Cica

2017
Verapamil inhibits interleukin-6 and vascular endothelial growth factor production in primary cultures of keloid fibroblasts.
    British journal of plastic surgery, 2003, Volume: 56, Issue:8

    Topics: Analysis of Variance; Apoptosis; Calcium Channel Blockers; Cell Division; Cells, Cultured; Fibroblas

2003
Prevention and treatment of keloids with intralesional verapamil.
    Dermatology (Basel, Switzerland), 2004, Volume: 209, Issue:1

    Topics: Adolescent; Adult; Female; Humans; Injections, Intralesional; Keloid; Male; Treatment Outcome; Verap

2004
Treatment of earlobe keloids with surgery plus adjuvant intralesional verapamil and pressure earrings.
    Annals of plastic surgery, 1996, Volume: 37, Issue:2

    Topics: Adolescent; Adult; Calcium Channel Blockers; Child; Ear, External; Female; Humans; Keloid; Male; Mid

1996